Title:Nutraceuticals Health Benefits in Cancer
Volume: 1
Author(s): Sunam Saha, Shivendra Kumar*, Bhawna Sharma, Shuchita Mishra, Shubham Singh, Arun Kumar Chaturvedi, Ravindra Patel and Mohit Agrawal
Affiliation:
- Department of Pharmaceutical Chemistry, Rajiv Academy for Pharmacy, Mathura, Uttar Pradesh, India
Keywords:
Polyphenols, bergamot, oleuropein, quercetin, curcumin, apoptosis.
Abstract: Cancer is one of the leading causes of death worldwide, with multiple pathological components.
Genetic abnormalities, infection or inflammation, poor diet, radiation exposure, work
stress, and/or ingestion of toxic substances have all been associated with cancer development and
progression. Early detection and treatment of cancer have been shown to increase the chances of
survival and recovery and reduce the side effects of anticancer drugs. Anticancer drugs continue to
cause negative side effects that negate treatment benefits in terms of hospitalization and survival.
Many naturally occurring bioactive compounds are shown to have anticancer properties. That is,
they can eliminate altered and cancer cells without harming their healthy counterparts. In particular,
the following activities have been reported to support nutrition during cancer treatment: cell growth
inhibition, antioxidant activity, anti-inflammatory activity, and minimized negative effects due to
natural antioxidants. Keeping the side effects minimum helps patients adhere to anticancer therapy.
Among currently available anticancer agents, dietary supplementation can be considered in conjunction
with current chemotherapy to improve response and compliance in cancer patients. However, it
should be noted that before discussing data from studies on bioactive plant supplements, it is important
to ensure that the tests were performed according to protocol.