Title:Preparation and Chemical/Physical Characterization of Individual Nanoscaled
Fibrils
Volume: 12
Issue: 2
Author(s): Praveetha Senthilkumar, Sharmila Chandran, Alexey Kartsev, Vladimir Shavrov, Petr Lega and Ramesh Subramani*
Affiliation:
- Department of Food Processing Technology and Management, PSGR Krishnammal College for Women, Coimbatore,
India
Keywords:
Nanofibrils, electrostatic interactions, self-assembly, mechanical measurement, atomic force microscopy, nano tweezers.
Abstract: Polymer-based nanofibril finds its application in various fields including tissue engineering,
environmental monitoring, food packaging, and micro/nanoelectromechanical systems. These nanofibrils
are subjected to chemical treatment and constant stress, which may cause permanent deformation to the
fibrils when it is used. Therefore, the synthesis of well-defined nanofibrils and characterization techniques
are key elements in identifying desired chemical and physical properties for suitable applications. Many
methods have been developed to prepare individual nanofibrils, including electrospinning, phase separation,
template synthesis, and self-assembly. Among all, self-assembly offers simple, efficient, and lowcost
strategies that produce high-ordered nanofibrils using noncovalent interactions including hydrogen
bonding, electrostatic interactions, π-π interactions, and hydrophobic interactions. The first part of the
review provides detailed molecular interactions and simulations that can be controlled to achieve the formation
of well-defined individual nanofibrils. The second part of the review describes the various existing
tools to characterize the chemical and physical properties of single nanofibrils including atomic force
microscopy. In the final part of the review, recently developed novel nanotools that measure the mechanical
properties of nanofibrils are described. By bridging the gap between molecular interactions and resulting
nanoscale fibirls, physical and chemical properties may lead to the construction of novel nanomaterials
in the area of nanoscience and nanotechnology.