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Reviews on Recent Clinical Trials

Volume 15, 4 Issues, 2020
ISSN: 1876-1038 (Online)
ISSN: 1574-8871 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Reviews on Recent Clinical Trials publishes high quality full-length/mini reviews, original research articles, interesting case reports, drug clinical trial studies and guest edited thematic issues on recent clinical trials of major importance. The journal's aim is to publish the highest quality articles in the field. Topics covered include: important Phase I – IV clinical trial studies, clinical investigations at all stages of development, therapeutics, meta analysis, trial logistics, design and conduct of trials, statistical methods, synthesis and evidence evaluation, decision analysis, reviews, case reports and commentaries on current or controversial issues.

The journal is essential reading for all researchers and clinicians involved in drug therapy and clinical trials.

Reviews on Recent Clinical Trials


Volume 15


Number 3

Biography   Open Access

Editorial   Open Access

Review Article

Light Alcohol Drinking and the Risk of Cancer Development: A Controversial Relationship

, 15(3): 164 - 177

Giuseppe G. Caprio, Desiree Picascia, Marcello Dallio*, Pietro P. Vitiello, Emilio F. Giunta, Vincenzo De Falco, Ludovico Abenavoli, Anna C. Procopio, Vincenzo Famiglietti, Erika Martinelli, Antonietta G. Gravina, Alessandro Federico, Fortunato Ciardiello, Carmelina Loguercio and Davide Ciardiello

DOI: 10.2174/1574887115666200628143015

Review Article

Review Article   Open Access

Review Article (Mini-Review)

Research Article

Structural and Morphological Changes in the Liver Due to Intestinal Endotoxins

, 15(3): 205 - 213

Alexander L. Malev, Anna N. Zakharova, Vitalii B. Kaliberdenko, Tatyana A. Fominykh, Shanmugaraj Kulanthaivel* and Keerthanaa Balasundaram

DOI: 10.2174/1574887115666200617143422

Research Article

Articles Ahead of Print

Tocilizumab in Sars-cov-2 Patients with the Syndrome of Cytokine Storm; a Narrative review

Shanmugaraj Kulanthaivel*, Vitalii B. Kaliberdenko, Keerthanaa Balasundaram, Michael V. Shterenshis, Emidio Scarpellini and Ludovico Abenavoli

DOI: 10.2174/1574887115666200917110954
View Abstract

Radiation-Induced Oral Mucositis in Head and Neck Cancer Patients. Is There Any Effective Management? Review of the Literature of the Last Five Years

Areti Gkantaifi*, Emmanouil Vardas, Filippo Alongi, Nikolaos Tsoukalas, Haytham Hamed Saraireh, Nikolaos Charalampakis, Lövey Jozsef, Jiannis Hajiioannou, Efthymios Kyrodimos, Konstantinos Tsanadis, Mauri Davide, Christopoulos Christos, George Iliadis and Maria Tolia

DOI: 10.2174/1574887115666200731182708
View Abstract View on PubMed

Bedside Cardiac Pocus in Emergency Setting: A Practice Review

Christian Zanza*, Yaroslava Longhitano, Marco Artico, Gianmaria Cammarota, Andrea Barbanera, Fabrizio Racca, Andrea Audo, Enrico Ravera, Alessio Migneco, Andrea Piccioni and Francesco Franceschi

DOI: 10.2174/1574887115666200802023306
View Abstract View on PubMed

Gut Alterations in Septic Patients: A Biochemical Literature Review

Yaroslava Longhitano*, Christian Zanza, Duraiyah Thangathurai, Samanta Taurone, Daniela Kozel, Fabrizio Racca, Andrea Audo, Enrico Ravera, Alessio Migneco, Andrea Piccioni and Francesco Franceschi

DOI: 10.2174/1574887115666200811105251
View Abstract

Metabolic Benefits of Probiotic Combination with Absorbent Smectite in type 2 Diabetes Patients A randomised Controlled Trial

Nazarii Kobyliak*, Ludovico Abenavoli, Tetyana Falalyeyeva, Oleksandr Kovalchuk, Dmytro Kyriienko and Iuliia Komisarenko

DOI: 10.2174/1574887115666200709141131
View Abstract View on PubMed

An Approach to Diabetic Ketoacidosis in an Emergency Setting

Dario Pitocco*, Mauro Di Leo, Linda Tartaglione, Emanuele Gaetano Rizzo, Salvatore Caputo, Alessandro Rizzi and Alfredo Pontecorvi

DOI: 10.2174/1574887115666200709172402
View Abstract View on PubMed

Honey Against Radiation-induced Oral Mucositis in Head and Neck Cancer Patients. An Umbrella Review of Systematic Reviews and Meta-Analyses of the Literature

Areti Gkantaifi*, Filippo Alongi, Emmanouil Vardas, Francesco Cuccia, Jiannis Hajiioannou, Efthymios Kyrodimos, Christos Christopoulos, Davide Mauri, Nikolaos Charalampakis, Nikolaos Trogkanis, Nikolaos Tsoukalas, George Iliadis and Maria Tolia

DOI: 10.2174/1574887115666200709140405
View Abstract View on PubMed

Management of Immunotherapy Adverse Events in Oncological Patients: Anti-CTLA-4, Anti-PD-1/PD-L1

Mattia Brigida, Alessia Perricelli, Fausto Sposato, Maria Giovanna Spadafora, Angelo Pomillo and Sisto Milito *

DOI: 10.2174/1574887115666200622161418
View Abstract View on PubMed

Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Serum Levels of Granulocyte-Macrophage-colony-stimulating Factor and Stem-cell Factor During Liver Regeneration after Partial Hepatectomy in Humans

, 2020; 15(2): 131 - 136

Diego Fiume , Ilaria Lenci, Martina Milana, Tommaso M. Manzia, Renato Massoud, Laura Tariciotti, Carmelo Russo, Luca Toti and Leonardo Baiocchi*

DOI: 10.2174/1574887115666200123113623

An Industry Perspective on Risks and Mitigation Strategies Associated with Post Conduct Phase of Clinical Trial

, 2020; 15(1): 28 - 33

Seema Bhagat*, Vaibhavi K. Kapatkar, Ashish Mane, Colette Pinto, Devang Parikh, Gaurav Mittal and Rishi Jain

DOI: 10.2174/1574887114666191016103332

Domino Liver Transplantation: Where are we Now?

, 2019; 14(3): 183 - 188

Francesco Santopaolo, Ilaria Lenci, Alessandra Bosa, Mario Angelico, Martina Milana and Leonardo Baiocchi*

DOI: 10.2174/1574887114666190320123824

Impact of a Psycho-Educational Team in early Breast Cancer Patients’ Coping Strategies: The Venere Project

, 2018; 13(4): 274 - 280

Federica Andreis, Fausto Meriggi*, Claudio Codignola, Ilaria Frigoli, Tiziana Prochilo, Stefano Mutti, Alessandra Huscher, Michela Libertini, Brunella Di Biasi, Chiara Abeni, Chiara Ogliosi, Silvia Noventa, Luigina Rota, Chiara Pedrali and Alberto Zaniboni

DOI: 10.2174/1574887113666180409152025

The Emerging Role of IL-1 Inhibition in Patients Affected by Rheumatoid Arthritis and Diabetes

, 2018; 13(3): 210 - 214

Piero Ruscitti*, Paola Cipriani, Vasiliky Liakouli, Francesco Carubbi, Onorina Berardicurti, Paola Di Benedetto, Francesco Ciccia, Giuliana Guggino, Saverio Alvaro, Giovanni Triolo and Roberto Giacomelli

DOI: 10.2174/1574887113666180314102651

Cardiovascular Disease in Primary Sjögren’s Syndrome

, 2018; 13(3): 164 - 169

Onorina Berardicurti*, Piero Ruscitti, Paola Cipriani, Francesco Ciccia, Vasiliki Liakouli, Giuliana Guggino, Francesco Carubbi, Paola Di Benedetto, Giovanni Triolo and Roberto Giacomelli

DOI: 10.2174/1574887113666180315130336

Evaluating the Effect of Oral N-acetylcysteine as an Adjuvant Treatment on Clinical Outcomes of Patients with Rheumatoid Arthritis: A Randomized, Double Blind Clinical Trial

, 2018; 13(2): 132 - 138

Minoo Batooei, Ahmad Tahamoli-Roudsari, Zahra Basiri, Fatemeh Yasrebifar, Maryam Shahdoust, Azadeh Eshraghi, Maryam Mehrpooya* and Sara Ataei

DOI: 10.2174/1574887113666180307151937

Open Access Articles

Review on Recent Trials Evaluating the Effect of Intravitreal Injections of Anti-VEGF Agents on the Macular Perfusion of Diabetic Patients with Diabetic Macular Edema

, 2020; 15(3): 188 - 198

Ayman G. Elnahry*, Ahmed A. Abdel-Kader, Ahmed E. Habib, Gehad A. Elnahry, Karim A. Raafat and Khaled Elrakhawy

Thrombosed External Haemorrhoids: A Clinician’s Dilemma

, 2019; 14(4): 232 - 234

Giuseppe Sammarco, Mario Trompetto and Gaetano Gallo

Cardiovascular Risk Markers and Major Adverse Cardiovascular Events in Psoriatic Arthritis Patients

, 2018; 13(3): 199 - 209

Rosario Peluso*, Francesco Caso, Marco Tasso, Pasquale Ambrosino, Matteo Nicola Dario Di Minno, Roberta Lupoli, Livio Criscuolo, Paolo Caso, Francesco Ursini, Antonio Del Puente, Raffaele Scarpa and Luisa Costa on behalf of CaRRDs study group

Point-of-Care Lung Ultrasound in Critically ill Patients

, 2018; 13(1): 15 - 26

Gentle S. Shrestha*, Dameera Weeratunga and Kylie Baker

Treating Older HIV-1-infected Subjects With Cobicistat-boosted Darunavir in a 48-week Phase 3 Trial

, 2017; 12(3): 174 - 181

Kimberley Brown*, Brooke Patterson-Browning, Chris Liu, Meera Patel, Lisa Stewart and Richard E. Nettles

Neoadjuvant Therapy for HER2-positive Breast Cancer

, 2017; 12(2): 81 - 92

Rachel Wuerstlein* and Nadia Harbeck

Managing Expectations in the Transition to Proof of Concept Studies

, 2017; 12(2): 111 - 123

Thomas Kieber-Emmons*, Issam Makhoul, Angela Pennisi, Eric R. Siegel, Peter D. Emanuel, Bejotaloh Monzavi-Karbassi, Zenon Steplewski, J. Thaddeus Beck and Laura F. Hutchins

Potential Risks and Mitigation Strategies Before the Conduct of a Clinical Trial: An Industry Perspective

, 2016; 11(1): 47 - 55

Seema Bhagat, Vaibhavi K. Kapatkar, Meenakshi Mourya, Sucheta Roy, Shailendra Jha, Rajasekhar Reddy, Ganesh Kadhe, Amey Mane and Sandesh Sawant

Parallel Conduction of the Phase I Preventive and Therapeutic Trials Based on the Tat Vaccine Candidate

, 2009; 4(3): 195 - 204

S. Bellino, V. Francavilla, O. Longo, A. Tripiciano, G. Paniccia, A. Arancio, V. Fiorelli, A. Scoglio, B. Collacchi, M. Campagna, A. Lazzarin, G. Tambussi, C. Tassan Din, R. Visintini, P. Narciso, A. Antinori, G. D'Offizi, M. Giulianelli, M. Carta, A. Di Carlo, G. Palamara, M. Giuliani, M. E. Laguardia, P. Monini, M. Magnani, F. Ensoli and B. Ensoli

Most Cited Articles

Review Article

A concise history of thiopurines for inflammatory bowel disease: From anecdotal reporting to treat-to-target algorithms

, 2019; 14(1): 4-9.

Giovanni Clemente Actis*, Rinaldo Pellicano and Davide Giuseppe Ribaldone

DOI: 10.2174/1574887113666180910120959

Review Article

Real-world efficacy and safety of pangenotypic direct-acting antivirals against hepatitis C virus infection

, 2019; 14(3): 173-182.

Riccardo Scotto, Antonio Riccardo Buonomo*, Nicola Schiano Moriello, Alberto Enrico Maraolo, Emanuela Zappulo, Biagio Pinchera, Ivan Gentile and Guglielmo Borgia

DOI: 10.2174/1574887114666190306154650

Systemic Review Article

Effect of kangaroo mother care on successful breastfeeding: A systematic review and meta-analysis of randomised controlled trials

, 2019; 14(1): 31-40.

Morteza Ghojazadeh, Sakineh Hajebrahimi, Fatemeh Pournaghi-Azar, Mohammad Mohseni, Naser Derakhshani and Saber Azami-Aghdash*

DOI: 10.2174/1574887113666180924165844

Research Article

Effect of chondroitin sulfate on blood serum cytokine profile during carrageenan-induced edema and monoiodoacetate-induced osteoarthritis in rats

, 2019; 14(1): 50-55.

Oleksandr Korotkyi*, Andrii Vovk, Oksana Blokhina, Kateryna Dvorshchenko, Tetyana Falalyeyeva, Ludovico Abenavoli and Liudmyla Ostapchenko

DOI: 10.2174/1574887113666181102111247


Epidemiology of coronavirus disease outbreak: The Italian trends

, 2020; 15(2): 87-92.

Ludovico Abenavoli*, Pietro Cinaglia, Francesco Luzza, Ivan Gentile and Luigi Boccuto

DOI: 10.2174/1574887115999200407143449

Review Article

The role of Biofilm in central venous catheter related bloodstream infections: Evidence-based nursing and review of the literature

, 2020; 15(1): 22-27.

Nicola Ielapi, Emanuela Nicoletti, Carmela Lorè, Giorgio Guasticchi, Tiziana Avenoso, Andrea Barbetta, Stefano de Franciscis, Michele Andreucci, Paolo Sapienza and Raffaele Serra*

DOI: 10.2174/1574887114666191018144739

Systemic Review Article

High flow through nasal cannula in stable and exacerbated chronic obstructive pulmonary disease patients

, 2019; 14(4): 247-260.

Andrea Bruni, Eugenio Garofalo, Gianmaria Cammarota, Paolo Murabito, Marinella Astuto, Paolo Navalesi, Francesco Luzza, Ludovico Abenavoli and Federico Longhini*

DOI: 10.2174/1574887114666190710180540

Clinical Trial

Intravenous tranexamic acid for subdural and epidural intracranial hemorrhage: Randomized, double‐blind, placebo-controlled trial

, 2019; 14(4): 286-291.

Pouya Ebrahimi, Javad Mozafari*, Reza Bahrami Ilkhchi, Mohammad Ghasem Hanafi and Maryam Mousavinejad

DOI: 10.2174/1574887114666190620112829

General Review Article

Advanced non-small cell lung cancer with activating epidermal growth factor receptor mutation: First line treatment and beyond

, 2019; 14(2): 120-128.

Danilo Rocco, Ciro Battiloro , Luigi Della Gravara and Cesare Gridelli*

DOI: 10.2174/1574887114666181205155211

Case Report

Successful use of aliskiren in a case of IgA-Mesangial glomerulonephritis unresponsive to conventional therapies

, 2019; 14(1): 72-76.

Mariadelina Simeoni*, Ramona Nicotera, Elena Pelagi, Emanuela Libri, Nicolino Comi and Giorgio Fuiano

DOI: 10.2174/1574887113666180726103648

Clinical Trial

Hair loss prevention by a scalp cooling device in early breast cancer patients: The poliambulanza preliminary experience

, 2019; 14(1): 66-71.

Tiziana Prochilo*, Alessandra Huscher, Federica Andreis , Mara Mirandola, Elisabetta Zaina, Barbara Pomentale, Chiara Pedrali, Laura Zanotti, Stefano Mutti and Alberto Zaniboni

DOI: 10.2174/1574887113666181120111104


Thrombosed external haemorrhoids: A clinician’s dilemma

, 2019; 14(4): 232-234.

Giuseppe Sammarco, Mario Trompetto and Gaetano Gallo

DOI: 10.2174/1574887114666190927163646

Review Article

Domino liver transplantation: Where are we now?

, 2019; 14(3): 183-188.

Francesco Santopaolo, Ilaria Lenci, Alessandra Bosa, Mario Angelico, Martina Milana and Leonardo Baiocchi*

DOI: 10.2174/1574887114666190320123824

Review Article

A review of clinical data management systems used in clinical trials

, 2019; 14(1): 10-23.

Aynaz Nourani, Haleh Ayatollahi* and Masoud Solaymani Dodaran

DOI: 10.2174/1574887113666180924165230

Most Accessed Articles

Benign Intracranial Lesions - Radiotherapy: An Overview of Treatment Options, Indications and Therapeutic Results

, 2020; 15(2): 93-121.

Vasileios Tzikoulis, Areti Gkantaifi, Filippo Alongi, Nikolaos Tsoukalas, Haytham Hamed Saraireh, Nikolaos Charalampakis, Georgios Tzikoulis, Emmanouil Andreou, Konstantinos Tsapakidis, Dimitrios Kardamakis, Konstantinos Tsanadis, George Kyrgias and Maria Tolia*

DOI: 10.2174/1574887114666191111100635

Point-of-Care Lung Ultrasound in Critically ill Patients

, 2018; 13(1): 15-26.

Gentle S. Shrestha*, Dameera Weeratunga and Kylie Baker

DOI: 10.2174/1574887112666170911125750

Barriers and Facilitators in Conducting Clinical Trials in Inflammatory Bowel Disease: A Monocentric Italian Survey

, 2020; 15(2): 137-144.

Tiziana Larussa*, Evelina Suraci, Raffaella Marasco, Maria Imeneo, Dan L. Dumitrascu, Ludovico Abenavoli and Francesco Luzza

DOI: 10.2174/1574887115666200224113520

The Role of Biofilm in Central Venous Catheter Related Bloodstream Infections: Evidence-based Nursing and Review of the Literature

, 2020; 15(1): 22-27.

Nicola Ielapi, Emanuela Nicoletti, Carmela Lorè, Giorgio Guasticchi, Tiziana Avenoso, Andrea Barbetta, Stefano de Franciscis, Michele Andreucci, Paolo Sapienza and Raffaele Serra*

DOI: 10.2174/1574887114666191018144739


Ludovico Abenavoli
University Magna Graecia
View Full Editorial Board

Journal History

Reviews on Recent Clinical Trials Journal was launched in 2006. Dr. Ludovico Abenavoli serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.01


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