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Reviews on Recent Clinical Trials

Volume 15, 4 Issues, 2020
ISSN: 1876-1038 (Online)
ISSN: 1574-8871 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Reviews on Recent Clinical Trials publishes high quality full-length/mini reviews, original research articles, interesting case reports, drug clinical trial studies and guest edited thematic issues on recent clinical trials of major importance. The journal's aim is to publish the highest quality articles in the field. Topics covered include: important Phase I – IV clinical trial studies, clinical investigations at all stages of development, therapeutics, meta analysis, trial logistics, design and conduct of trials, statistical methods, synthesis and evidence evaluation, decision analysis, reviews, case reports and commentaries on current or controversial issues.

The journal is essential reading for all researchers and clinicians involved in drug therapy and clinical trials.

Reviews on Recent Clinical Trials

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Volume 15

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Number 2



Biography   Open Access



Editorial   Open Access



Editorial   Open Access

Epidemiology of Coronavirus Disease Outbreak: The Italian Trends

, 15(2): 87 - 92

Ludovico Abenavoli*, Pietro Cinaglia, Francesco Luzza, Ivan Gentile and Luigi Boccuto


DOI: 10.2174/1574887115999200407143449


Review Article

Benign Intracranial Lesions - Radiotherapy: An Overview of Treatment Options, Indications and Therapeutic Results

, 15(2): 93 - 121

Vasileios Tzikoulis, Areti Gkantaifi, Filippo Alongi, Nikolaos Tsoukalas, Haytham Hamed Saraireh, Nikolaos Charalampakis, Georgios Tzikoulis, Emmanouil Andreou, Konstantinos Tsapakidis, Dimitrios Kardamakis, Konstantinos Tsanadis, George Kyrgias and Maria Tolia*


DOI: 10.2174/1574887114666191111100635


Review Article



Research Article

Serum Levels of Granulocyte-Macrophage-colony-stimulating Factor and Stem-cell Factor During Liver Regeneration after Partial Hepatectomy in Humans

, 15(2): 131 - 136

Diego Fiume , Ilaria Lenci, Martina Milana, Tommaso M. Manzia, Renato Massoud, Laura Tariciotti, Carmelo Russo, Luca Toti and Leonardo Baiocchi*


DOI: 10.2174/1574887115666200123113623


Research Article

Barriers and Facilitators in Conducting Clinical Trials in Inflammatory Bowel Disease: A Monocentric Italian Survey

, 15(2): 137 - 144

Tiziana Larussa*, Evelina Suraci, Raffaella Marasco, Maria Imeneo, Dan L. Dumitrascu, Ludovico Abenavoli and Francesco Luzza


DOI: 10.2174/1574887115666200224113520


Research Article

Circadian Rhythms of Endothelial Nitric Oxide Synthase and Toll-like Receptors 2 Production in Females with Rheumatoid Arthritis Depending on NOS3 Gene Polymorphism

, 15(2): 145 - 151

Kateryna Zaichko, Nataliia Zaichko, Oleksandr Maievskyi, Oleksandr Korotkyi, Tetyana Falalyeyeva, Sharmila Fagoonee, Rinaldo Pellicano, Ludovico Abenavoli and Mykola Stanislavchuk*


DOI: 10.2174/1574887115666200416143512


Articles Ahead of Print

An Approach to diabetic ketoacidosis in an emergency setting.


Dario Pitocco*, Mauro Di Leo, Linda Tartaglione, Emanuele Gaetano Rizzo, Salvatore Caputo, Alessandro Rizzi and Alfredo Pontecorvi


DOI: 10.2174/1574887115666200709172402
View Abstract



Metabolic benefits of probiotic combination with absorbent smectite in type 2 diabetes patients: a randomised controlled trial


Nazarii Kobyliak*, Ludovico Abenavoli, Tetyana Falalyeyeva, Oleksandr Kovalchuk, Dmytro Kyriienko and Iuliia Komisarenko


DOI: 10.2174/1574887115666200709141131
View Abstract


Honey against radiation induced oral mucositis in head and neck cancer patients. An Umbrella Review of Systematic Reviews and Meta-Analyses of the literature


Areti Gkantaifi*, Filippo Alongi, Emmanouil Vardas, Francesco Cuccia, Jiannis Hajiioannou, Efthymios Kyrodimos, Christos Christopoulos, Davide Mauri, Nikolaos Charalampakis, Nikolaos Trogkanis, Nikolaos Tsoukalas, George Iliadis and Maria Tolia


DOI: 10.2174/1574887115666200709140405
View Abstract


Structural and Morphological Changes In The Liver Due to Intestinal Endotoxins


Alexander L. Malev, Anna N. Zakharova, Vitalii B. Kaliberdenko, Tatyana A. Fominykh, Shanmugaraj Kulanthaivel* and Keerthanaa Balasundaram


DOI: 10.2174/1574887115666200617143422
View Abstract View on PubMed



Clinical Management of Infectious Diarrhea


Valentina Siciliano*, Enrico Celestino Nista, Tommaso Rosà, Mattia Brigida and Francesco Franceschi


DOI: 10.2174/1574887115666200628144128
View Abstract


Light alcohol drinking and the risk of cancer development: a controversial relationship


Giuseppe Gerardo Caprio, Desiree Picascia, Marcello Dallio*, Pietro Paolo Vitiello, Emilio Francesco Giunta, Vincenzo De Falco, Ludovico Abenavoli, Anna Caterina Procopio, Vincenzo Famiglietti, Erika Martinelli, Antonietta Gerarda Gravina, Alessandro Federico, Fortunato Ciardiello, Carmelina Loguercio and Davide Ciardiello


DOI: 10.2174/1574887115666200628143015
View Abstract



A Review on the Use of Reversal Agents of Direct Oral Anticogulant Drugs in Case of Gastrointestinal Bleeding


Veronica Ojetti*, Angela Saviano, Mattia Brigida, Luisa Saviano, Alessio Migneco and Francesco Franceschi


DOI: 10.2174/1574887115666200624193938
View Abstract


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Serum Levels of Granulocyte-Macrophage-colony-stimulating Factor and Stem-cell Factor During Liver Regeneration after Partial Hepatectomy in Humans

, 2020; 15(2): 131 - 136

Diego Fiume , Ilaria Lenci, Martina Milana, Tommaso M. Manzia, Renato Massoud, Laura Tariciotti, Carmelo Russo, Luca Toti and Leonardo Baiocchi*


DOI: 10.2174/1574887115666200123113623



An Industry Perspective on Risks and Mitigation Strategies Associated with Post Conduct Phase of Clinical Trial

, 2020; 15(1): 28 - 33

Seema Bhagat*, Vaibhavi K. Kapatkar, Ashish Mane, Colette Pinto, Devang Parikh, Gaurav Mittal and Rishi Jain


DOI: 10.2174/1574887114666191016103332



Domino Liver Transplantation: Where are we Now?

, 2019; 14(3): 183 - 188

Francesco Santopaolo, Ilaria Lenci, Alessandra Bosa, Mario Angelico, Martina Milana and Leonardo Baiocchi*


DOI: 10.2174/1574887114666190320123824





Impact of a Psycho-Educational Team in early Breast Cancer Patients’ Coping Strategies: The Venere Project

, 2018; 13(4): 274 - 280

Federica Andreis, Fausto Meriggi*, Claudio Codignola, Ilaria Frigoli, Tiziana Prochilo, Stefano Mutti, Alessandra Huscher, Michela Libertini, Brunella Di Biasi, Chiara Abeni, Chiara Ogliosi, Silvia Noventa, Luigina Rota, Chiara Pedrali and Alberto Zaniboni


DOI: 10.2174/1574887113666180409152025



The Emerging Role of IL-1 Inhibition in Patients Affected by Rheumatoid Arthritis and Diabetes

, 2018; 13(3): 210 - 214

Piero Ruscitti*, Paola Cipriani, Vasiliky Liakouli, Francesco Carubbi, Onorina Berardicurti, Paola Di Benedetto, Francesco Ciccia, Giuliana Guggino, Saverio Alvaro, Giovanni Triolo and Roberto Giacomelli


DOI: 10.2174/1574887113666180314102651



Cardiovascular Disease in Primary Sjögren’s Syndrome

, 2018; 13(3): 164 - 169

Onorina Berardicurti*, Piero Ruscitti, Paola Cipriani, Francesco Ciccia, Vasiliki Liakouli, Giuliana Guggino, Francesco Carubbi, Paola Di Benedetto, Giovanni Triolo and Roberto Giacomelli


DOI: 10.2174/1574887113666180315130336



Evaluating the Effect of Oral N-acetylcysteine as an Adjuvant Treatment on Clinical Outcomes of Patients with Rheumatoid Arthritis: A Randomized, Double Blind Clinical Trial

, 2018; 13(2): 132 - 138

Minoo Batooei, Ahmad Tahamoli-Roudsari, Zahra Basiri, Fatemeh Yasrebifar, Maryam Shahdoust, Azadeh Eshraghi, Maryam Mehrpooya* and Sara Ataei


DOI: 10.2174/1574887113666180307151937




Open Access Articles

Review on Recent Trials Evaluating the Effect of Intravitreal Injections of Anti-VEGF Agents on the Macular Perfusion of Diabetic Patients with Diabetic Macular Edema

, 2020; 15: 1 - 11 (E-Pub Ahead of Print)

Ayman G. Elnahry*, Ahmed A. Abdel-Kader, Ahmed E. Habib, Gehad A. Elnahry, Karim A. Raafat and Khaled Elrakhawy




Thrombosed External Haemorrhoids: A Clinician’s Dilemma

, 2019; 14(4): 232 - 234

Giuseppe Sammarco, Mario Trompetto and Gaetano Gallo






Cardiovascular Risk Markers and Major Adverse Cardiovascular Events in Psoriatic Arthritis Patients

, 2018; 13(3): 199 - 209

Rosario Peluso*, Francesco Caso, Marco Tasso, Pasquale Ambrosino, Matteo Nicola Dario Di Minno, Roberta Lupoli, Livio Criscuolo, Paolo Caso, Francesco Ursini, Antonio Del Puente, Raffaele Scarpa and Luisa Costa on behalf of CaRRDs study group




Point-of-Care Lung Ultrasound in Critically ill Patients

, 2018; 13(1): 15 - 26

Gentle S. Shrestha*, Dameera Weeratunga and Kylie Baker





Treating Older HIV-1-infected Subjects With Cobicistat-boosted Darunavir in a 48-week Phase 3 Trial

, 2017; 12(3): 174 - 181

Kimberley Brown*, Brooke Patterson-Browning, Chris Liu, Meera Patel, Lisa Stewart and Richard E. Nettles




Neoadjuvant Therapy for HER2-positive Breast Cancer

, 2017; 12(2): 81 - 92

Rachel Wuerstlein* and Nadia Harbeck




Managing Expectations in the Transition to Proof of Concept Studies

, 2017; 12(2): 111 - 123

Thomas Kieber-Emmons*, Issam Makhoul, Angela Pennisi, Eric R. Siegel, Peter D. Emanuel, Bejotaloh Monzavi-Karbassi, Zenon Steplewski, J. Thaddeus Beck and Laura F. Hutchins




Potential Risks and Mitigation Strategies Before the Conduct of a Clinical Trial: An Industry Perspective

, 2016; 11(1): 47 - 55

Seema Bhagat, Vaibhavi K. Kapatkar, Meenakshi Mourya, Sucheta Roy, Shailendra Jha, Rajasekhar Reddy, Ganesh Kadhe, Amey Mane and Sandesh Sawant






Parallel Conduction of the Phase I Preventive and Therapeutic Trials Based on the Tat Vaccine Candidate

, 2009; 4(3): 195 - 204

S. Bellino, V. Francavilla, O. Longo, A. Tripiciano, G. Paniccia, A. Arancio, V. Fiorelli, A. Scoglio, B. Collacchi, M. Campagna, A. Lazzarin, G. Tambussi, C. Tassan Din, R. Visintini, P. Narciso, A. Antinori, G. D'Offizi, M. Giulianelli, M. Carta, A. Di Carlo, G. Palamara, M. Giuliani, M. E. Laguardia, P. Monini, M. Magnani, F. Ensoli and B. Ensoli






Most Cited Articles

Review Article

A concise history of thiopurines for inflammatory bowel disease: From anecdotal reporting to treat-to-target algorithms

, 2019; 14(1): 4-9.

Giovanni Clemente Actis*, Rinaldo Pellicano and Davide Giuseppe Ribaldone


DOI: 10.2174/1574887113666180910120959


Review Article

Real-world efficacy and safety of pangenotypic direct-acting antivirals against hepatitis C virus infection

, 2019; 14(3): 173-182.

Riccardo Scotto, Antonio Riccardo Buonomo*, Nicola Schiano Moriello, Alberto Enrico Maraolo, Emanuela Zappulo, Biagio Pinchera, Ivan Gentile and Guglielmo Borgia


DOI: 10.2174/1574887114666190306154650


Research Article

Effect of chondroitin sulfate on blood serum cytokine profile during carrageenan-induced edema and monoiodoacetate-induced osteoarthritis in rats

, 2019; 14(1): 50-55.

Oleksandr Korotkyi*, Andrii Vovk, Oksana Blokhina, Kateryna Dvorshchenko, Tetyana Falalyeyeva, Ludovico Abenavoli and Liudmyla Ostapchenko


DOI: 10.2174/1574887113666181102111247


Review Article

The role of Biofilm in central venous catheter related bloodstream infections: Evidence-based nursing and review of the literature

, 2020; 15(1): 22-27.

Nicola Ielapi, Emanuela Nicoletti, Carmela Lorè, Giorgio Guasticchi, Tiziana Avenoso, Andrea Barbetta, Stefano de Franciscis, Michele Andreucci, Paolo Sapienza and Raffaele Serra*


DOI: 10.2174/1574887114666191018144739


Systemic Review Article

Effect of kangaroo mother care on successful breastfeeding: A systematic review and meta-analysis of randomised controlled trials

, 2019; 14(1): 31-40.

Morteza Ghojazadeh, Sakineh Hajebrahimi, Fatemeh Pournaghi-Azar, Mohammad Mohseni, Naser Derakhshani and Saber Azami-Aghdash*


DOI: 10.2174/1574887113666180924165844


Case Report

Successful use of aliskiren in a case of IgA-Mesangial glomerulonephritis unresponsive to conventional therapies

, 2019; 14(1): 72-76.

Mariadelina Simeoni*, Ramona Nicotera, Elena Pelagi, Emanuela Libri, Nicolino Comi and Giorgio Fuiano


DOI: 10.2174/1574887113666180726103648


Systemic Review Article

High flow through nasal cannula in stable and exacerbated chronic obstructive pulmonary disease patients

, 2019; 14(4): 247-260.

Andrea Bruni, Eugenio Garofalo, Gianmaria Cammarota, Paolo Murabito, Marinella Astuto, Paolo Navalesi, Francesco Luzza, Ludovico Abenavoli and Federico Longhini*


DOI: 10.2174/1574887114666190710180540


Clinical Trial

Intravenous tranexamic acid for subdural and epidural intracranial hemorrhage: Randomized, double‐blind, placebo-controlled trial

, 2019; 14(4): 286-291.

Pouya Ebrahimi, Javad Mozafari*, Reza Bahrami Ilkhchi, Mohammad Ghasem Hanafi and Maryam Mousavinejad


DOI: 10.2174/1574887114666190620112829


Review Article

A review of clinical data management systems used in clinical trials

, 2019; 14(1): 10-23.

Aynaz Nourani, Haleh Ayatollahi* and Masoud Solaymani Dodaran


DOI: 10.2174/1574887113666180924165230


Clinical Trial

Hair loss prevention by a scalp cooling device in early breast cancer patients: The poliambulanza preliminary experience

, 2019; 14(1): 66-71.

Tiziana Prochilo*, Alessandra Huscher, Federica Andreis , Mara Mirandola, Elisabetta Zaina, Barbara Pomentale, Chiara Pedrali, Laura Zanotti, Stefano Mutti and Alberto Zaniboni


DOI: 10.2174/1574887113666181120111104


Systemic Review Article

Efficacy and safety of non-steroidal anti-androgens in patients with metastatic prostate cancer: Meta-analysis of randomized controlled trials

, 2020; 15(1): 34-47.

Muhammed Rashid, Madhan Ramesh*, K. Shamshavali, Amit Dang, Himanshu Patel and Krishna Undela


DOI: 10.2174/1574887114666191105152404


Clinical Trial

Intravenous tranexamic acid for brain contusion with intraparenchymal hemorrhage: Randomized, double-blind, placebo-controlled trial

, 2020; 15(1): 70-75.

Maryam Mousavinejad, Javad Mozafari*, Reza Bahrami Ilkhchi, Mohammad Ghasem Hanafi and Pouya Ebrahimi


DOI: 10.2174/1574887114666191118111826




Editorial

Thrombosed external haemorrhoids: A clinician’s dilemma

, 2019; 14(4): 232-234.

Giuseppe Sammarco, Mario Trompetto and Gaetano Gallo


DOI: 10.2174/1574887114666190927163646



Most Accessed Articles


Point-of-Care Lung Ultrasound in Critically ill Patients

, 2018; 13(1): 15-26.

Gentle S. Shrestha*, Dameera Weeratunga and Kylie Baker


DOI: 10.2174/1574887112666170911125750




The Role of Biofilm in Central Venous Catheter Related Bloodstream Infections: Evidence-based Nursing and Review of the Literature

, 2020; 15(1): 22-27.

Nicola Ielapi, Emanuela Nicoletti, Carmela Lorè, Giorgio Guasticchi, Tiziana Avenoso, Andrea Barbetta, Stefano de Franciscis, Michele Andreucci, Paolo Sapienza and Raffaele Serra*


DOI: 10.2174/1574887114666191018144739




The Role of Hyperhomocysteinemia in the Development of Changes in the Lungs

, 2020; 15(1): 48-59.

Inga Samborska, Oleksandr Kovalchuk, Sharmila Fagoonee, Tetyana Falalyeyeva* and Oleksandr Maievskyi


DOI: 10.2174/1574887114666191114152235




Editor-in-Chief

Ludovico Abenavoli
University Magna Graecia
Catanzaro
(Italy)
Biography View Full Editorial Board

Journal History

Reviews on Recent Clinical Trials Journal was launched in 2006. Dr. Ludovico Abenavoli serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.01

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