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Reviews on Recent Clinical Trials

Volume 16, 4 Issues, 2021
ISSN: 1876-1038 (Online)
ISSN: 1574-8871 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Reviews on Recent Clinical Trials publishes high quality full-length/mini reviews, original research articles, interesting case reports, drug clinical trial studies and guest edited thematic issues on recent clinical trials of major importance. The journal's aim is to publish the highest quality articles in the field. Topics covered include: important Phase I – IV clinical trial studies, clinical investigations at all stages of development, therapeutics, meta analysis, trial logistics, design and conduct of trials, statistical methods, synthesis and evidence evaluation, decision analysis, reviews, case reports and commentaries on current or controversial issues.

The journal is essential reading for all researchers and clinicians involved in drug therapy and clinical trials.

Reviews on Recent Clinical Trials

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Volume 16

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Number 1





Preface   Open Access







Review Article

Classifications and Clinical Assessment of Haemorrhoids: The Proctologist’s Corner

, 16(1): 10 - 16

Arcangelo Picciariello*, Petr V. Tsarkov, Vincenzo Papagni, Sergey Efetov, Daniel R. Markaryan, Inna Tulina and Donato F. Altomare


DOI: 10.2174/1574887115666200312163940




Review Article

Management of Hemorrhoidal Disease in Special Conditions: A Word of Caution

, 16(1): 22 - 31

Paola Salusso, Valentina Testa, Sylvie Mochet, Alberto Arezzo, Marco Ettore Allaix, Antonio Salzano, Mario Morino and Massimiliano Mistrangelo*


DOI: 10.2174/1574887115666200406121308




Articles Ahead of Print

New Strategies for Clinical Trials in Autism Spectrum Disorder


Rini Pauly, Catherine A. Ziats, Ludovico Abenavoli, Charles E. Schwartz and Luigi Boccuto*


DOI: 10.2174/1574887115666201120093634
View Abstract


Review and Analysis of Massively Registered Clinical Trials of COVID-19 using the Text Mining Approach


Swayamprakash Patel*, Ashish Patel, Mruduka Patel, Umang Shah, Mehul Patel, Nilay Solanki and Suchita Patel


DOI: 10.2174/1574887115666201202110919
View Abstract View on PubMed


Impact of Covid-19 on Mental Health: An Overview


Minal M. Kshirsagar*, Arun S. Dodamani, Girija A. Dodamani, Vrushali R. Khobragade and Rahul N. Deokar


DOI: 10.2174/1574887115666210105122324
View Abstract


Intravenous Magnesium – Lidocaine - Ketorolac Cocktail for Postoperative Opioid Resistant Pain: A Case Series of Novel Rescue Therapy


Christian Zanza*, Yaroslava Longhitano, Edwin Lin, Jerry Luo, Marco Artico, Benedetta Savarese, Valeria Bonato, Andrea Piccioni, Francesco Franceschi, Samanta Taurone, Ludovico Abenavoli and Jack Marshall Berger


DOI: 10.2174/1574887115666201202105620
View Abstract View on PubMed


Pathogenetic Correction of the Enteric Insufficiency Syndrome in Patients with Advanced Peritonitis


Fedor N. Ilchenko, Sergey G. Grivenko, Igor V. Kaminsky, Yuriy V. Artemov, Evelina R. Kondratiuk, Vitalii B. Kaliberdenko, Shanmugaraj Kulanthaivel* and Keerthanaa Balasundaram


DOI: 10.2174/1574887115666201228151727
View Abstract






Erythema Pernio-Like in Four Adolescents in the Era of the Coronavirus- 2 Infection


Luigi Promenzio, Fabio Arcangeli, Elisabetta Cortis, Elisa Sama and Federico Longhini*


DOI: 10.2174/1574887115666201016153031
View Abstract View on PubMed


Abstracts Ahead of Print

Prevalence and Related Factors of Sarcopenia in Community-dwelling Elderly with Long-term Care Insurance


Masahiro Kitamura, Kazuhiro P. Izawa*, Kodai Ishihara, Hiroaki Matsuda, Soichiro Okamura and Koji Fujioka


DOI: 10.2174/1574887116666210211144446
View Abstract


Management of Leaks Following Laparoscopic Sleeve Gastrectomy Using Specifically Designed Large Covered Metal Stents


Carmelo Luigiano*, Milena Di Leo, Leonardo Henry Eusebi, Matteo Barabino, Enrico De Nicola, Marco Giovenzana, Enrico Opocher, Giuseppe Iabichino, Maria Angela Palamara, Giuseppa Giacobbe, Andrea Tortora, Clara Virgilio, Ludovico Abenavoli, Socrate Pallio and Pierluigi Consolo


DOI: 10.2174/1574887116666210204142417
View Abstract


Phase 1 Clinical Trials of Small Molecules: Evolution and State of the Art


John J. Sramek, Michael F. Murphy, Sherilyn Adcock, Jeffrey G. Stark and Neal R. Cutler*


DOI: 10.2174/1574887116666210204125844
View Abstract


The Clinical Difference between Gabapentin and Pregabalin: Data from a Pilot Comparative Trial.


Omar Gammoh*, Ahmed Al-Smadi, Mohammad Qassem Shawagfeh, Jawad Kasawneh, Sukaina Malkawi and Sima Zein


DOI: 10.2174/1574887116666210201110507
View Abstract


COVID-19 and Clinical Trials: Current Challenges and Future Directions


Vinay Singh*, Sandeep Garg, Monika Klimek, Rajeev Ranjan Sinha and Dinesh Dhanwal


DOI: 10.2174/1574887116666210122160705
View Abstract


Epidemiological Characteristics of 64 Covid-19 Patients in Errachidia Province (Darâa-Tafilalet region), Morocco: A Retrospective Analysis


Mourad Akdad, Youness Algharrass, Hafid Talha, Abdelaadim Babakhouya, Mohammed Ajebli, Ahlam Ech-cherrate and Mohamed Eddouks*


DOI: 10.2174/1574887116666210114161633
View Abstract


Published Contents

Editor's Choice

The Management of Hemorrhoidal Disease by Dearterialization and Mucopexy

, 2021; 16(1): 60 - 66

Veronica De Simone, Francesco Litta*, Angelo Parello, Paola Campennì, Raffaele Orefice, Angelo Alessandro Marra, Marta Goglia and Carlo Ratto


DOI: 10.2174/1574887115666200506091306



Indications for Non-Invasive Ventilation in Respiratory Failure

, 2020; 15(4): 251 - 257

Simone Maria Navarra, Maria Teresa Congedo and Mariano Alberto Pennisi*


DOI: 10.2174/1574887115666200603151838




Serum Levels of Granulocyte-Macrophage-colony-stimulating Factor and Stem-cell Factor During Liver Regeneration after Partial Hepatectomy in Humans

, 2020; 15(2): 131 - 136

Diego Fiume , Ilaria Lenci, Martina Milana, Tommaso M. Manzia, Renato Massoud, Laura Tariciotti, Carmelo Russo, Luca Toti and Leonardo Baiocchi*


DOI: 10.2174/1574887115666200123113623



An Industry Perspective on Risks and Mitigation Strategies Associated with Post Conduct Phase of Clinical Trial

, 2020; 15(1): 28 - 33

Seema Bhagat*, Vaibhavi K. Kapatkar, Ashish Mane, Colette Pinto, Devang Parikh, Gaurav Mittal and Rishi Jain


DOI: 10.2174/1574887114666191016103332



Domino Liver Transplantation: Where are we Now?

, 2019; 14(3): 183 - 188

Francesco Santopaolo, Ilaria Lenci, Alessandra Bosa, Mario Angelico, Martina Milana and Leonardo Baiocchi*


DOI: 10.2174/1574887114666190320123824





Impact of a Psycho-Educational Team in early Breast Cancer Patients’ Coping Strategies: The Venere Project

, 2018; 13(4): 274 - 280

Federica Andreis, Fausto Meriggi*, Claudio Codignola, Ilaria Frigoli, Tiziana Prochilo, Stefano Mutti, Alessandra Huscher, Michela Libertini, Brunella Di Biasi, Chiara Abeni, Chiara Ogliosi, Silvia Noventa, Luigina Rota, Chiara Pedrali and Alberto Zaniboni


DOI: 10.2174/1574887113666180409152025



The Emerging Role of IL-1 Inhibition in Patients Affected by Rheumatoid Arthritis and Diabetes

, 2018; 13(3): 210 - 214

Piero Ruscitti*, Paola Cipriani, Vasiliky Liakouli, Francesco Carubbi, Onorina Berardicurti, Paola Di Benedetto, Francesco Ciccia, Giuliana Guggino, Saverio Alvaro, Giovanni Triolo and Roberto Giacomelli


DOI: 10.2174/1574887113666180314102651



Open Access Articles


Review on Recent Trials Evaluating the Effect of Intravitreal Injections of Anti-VEGF Agents on the Macular Perfusion of Diabetic Patients with Diabetic Macular Edema

, 2020; 15(3): 188 - 198

Ayman G. Elnahry*, Ahmed A. Abdel-Kader, Ahmed E. Habib, Gehad A. Elnahry, Karim A. Raafat and Khaled Elrakhawy




Thrombosed External Haemorrhoids: A Clinician’s Dilemma

, 2019; 14(4): 232 - 234

Giuseppe Sammarco, Mario Trompetto and Gaetano Gallo






Cardiovascular Risk Markers and Major Adverse Cardiovascular Events in Psoriatic Arthritis Patients

, 2018; 13(3): 199 - 209

Rosario Peluso*, Francesco Caso, Marco Tasso, Pasquale Ambrosino, Matteo Nicola Dario Di Minno, Roberta Lupoli, Livio Criscuolo, Paolo Caso, Francesco Ursini, Antonio Del Puente, Raffaele Scarpa and Luisa Costa on behalf of CaRRDs study group




Point-of-Care Lung Ultrasound in Critically ill Patients

, 2018; 13(1): 15 - 26

Gentle S. Shrestha*, Dameera Weeratunga and Kylie Baker





Treating Older HIV-1-infected Subjects With Cobicistat-boosted Darunavir in a 48-week Phase 3 Trial

, 2017; 12(3): 174 - 181

Kimberley Brown*, Brooke Patterson-Browning, Chris Liu, Meera Patel, Lisa Stewart and Richard E. Nettles




Neoadjuvant Therapy for HER2-positive Breast Cancer

, 2017; 12(2): 81 - 92

Rachel Wuerstlein* and Nadia Harbeck




Managing Expectations in the Transition to Proof of Concept Studies

, 2017; 12(2): 111 - 123

Thomas Kieber-Emmons*, Issam Makhoul, Angela Pennisi, Eric R. Siegel, Peter D. Emanuel, Bejotaloh Monzavi-Karbassi, Zenon Steplewski, J. Thaddeus Beck and Laura F. Hutchins




Potential Risks and Mitigation Strategies Before the Conduct of a Clinical Trial: An Industry Perspective

, 2016; 11(1): 47 - 55

Seema Bhagat, Vaibhavi K. Kapatkar, Meenakshi Mourya, Sucheta Roy, Shailendra Jha, Rajasekhar Reddy, Ganesh Kadhe, Amey Mane and Sandesh Sawant






Parallel Conduction of the Phase I Preventive and Therapeutic Trials Based on the Tat Vaccine Candidate

, 2009; 4(3): 195 - 204

S. Bellino, V. Francavilla, O. Longo, A. Tripiciano, G. Paniccia, A. Arancio, V. Fiorelli, A. Scoglio, B. Collacchi, M. Campagna, A. Lazzarin, G. Tambussi, C. Tassan Din, R. Visintini, P. Narciso, A. Antinori, G. D'Offizi, M. Giulianelli, M. Carta, A. Di Carlo, G. Palamara, M. Giuliani, M. E. Laguardia, P. Monini, M. Magnani, F. Ensoli and B. Ensoli





Most Cited Articles


Editorial

Epidemiology of coronavirus disease outbreak: The Italian trends

, 2020; 15(2): 87-92.

Ludovico Abenavoli*, Pietro Cinaglia, Francesco Luzza, Ivan Gentile and Luigi Boccuto


DOI: 10.2174/1574887115999200407143449


Review Article

The role of Biofilm in central venous catheter related bloodstream infections: Evidence-based nursing and review of the literature

, 2020; 15(1): 22-27.

Nicola Ielapi, Emanuela Nicoletti, Carmela Lorè, Giorgio Guasticchi, Tiziana Avenoso, Andrea Barbetta, Stefano de Franciscis, Michele Andreucci, Paolo Sapienza and Raffaele Serra*


DOI: 10.2174/1574887114666191018144739


Clinical Trial

Intravenous tranexamic acid for brain contusion with intraparenchymal hemorrhage: Randomized, double-blind, placebo-controlled trial

, 2020; 15(1): 70-75.

Maryam Mousavinejad, Javad Mozafari*, Reza Bahrami Ilkhchi, Mohammad Ghasem Hanafi and Pouya Ebrahimi


DOI: 10.2174/1574887114666191118111826


Review Article

Bedside cardiac pocus in emergency setting: A practice review

, 2020; 15(4): 269-277.

Christian Zanza*, Yaroslava Longhitano, Marco Artico, Gianmaria Cammarota, Andrea Barbanera, Fabrizio Racca, Andrea Audo, Enrico Ravera, Alessio Migneco, Andrea Piccioni and Francesco Franceschi


DOI: 10.2174/1574887115666200802023306


Review Article

Indications for non-invasive ventilation in respiratory failure

, 2020; 15(4): 251-257.

Simone Maria Navarra, Maria Teresa Congedo and Mariano Alberto Pennisi*


DOI: 10.2174/1574887115666200603151838


Review Article

Management of gastrointestinal bleeding in rendu-osler disease

, 2020; 15(4): 321-327.

Annalisa Tortora*, Clelia Marmo, Antonio Gasbarrini, Guido Costamagna and Maria Elena Riccioni


DOI: 10.2174/1574887115666200603160033


Review Article

An approach to diabetic ketoacidosis in an emergency setting

, 2020; 15(4): 278-288.

Dario Pitocco*, Mauro Di Leo, Linda Tartaglione, Emanuele Gaetano Rizzo, Salvatore Caputo, Alessandro Rizzi and Alfredo Pontecorvi


DOI: 10.2174/1574887115666200709172402


Review Article

Disk battery ingestion: A simple user-guide

, 2020; 15(4): 328-330.

Carmine Petruzziello* and Paolo Maurizio Soave


DOI: 10.2174/1574887115666200603163448


Review Article

Management of immunotherapy adverse events in oncological patients: Anti-ctla-4, anti-pd-1/pd-l1

, 2020; 15(4): 339-346.

Mattia Brigida, Alessia Perricelli, Fausto Sposato, Maria Giovanna Spadafora, Angelo Pomillo and Milito Sisto*


DOI: 10.2174/1574887115666200622161418


Review Article

Clinical management of infectious diarrhea

, 2020; 15(4): 298-308.

Valentina Siciliano*, Enrico Celestino Nista, Tommaso Rosà, Mattia Brigida and Francesco Franceschi


DOI: 10.2174/1574887115666200628144128


Review Article

Liver cirrhosis complications management at the emergency department

, 2020; 15(4): 331-338.

Emidio Scarpellini, Carmelo Luigiano, Gianluca Svegliati-Baroni, Dan Dumitrascu, Tiziana Larussa, Valeria Santori, Francesco Luzza and Ludovico Abenavoli*


DOI: 10.2174/1574887115666200603160816


Review Article

Management of pleural effusions in the emergency department

, 2020; 15(4): 258-268.

Maria Teresa Congedo*, Gian Maria Ferretti, Dania Nachira and Mariano Alberto Pennisi


DOI: 10.2174/1574887115666200624194457


Review Article

A review on the use of reversal agents of direct oral anticogulant drugs in case of gastrointestinal bleeding

, 2020; 15(4): 309-320.

Veronica Ojetti*, Angela Saviano, Mattia Brigida, Luisa Saviano, Alessio Migneco and Francesco Franceschi


DOI: 10.2174/1574887115666200624193938


Review Article

Gut alterations in septic patients: A biochemical literature review

, 2020; 15(4): 289-297.

Yaroslava Longhitano*, Christian Zanza, Duraiyah Thangathurai, Samanta Taurone, Daniela Kozel, Fabrizio Racca, Andrea Audo, Enrico Ravera, Alessio Migneco, Andrea Piccioni and Francesco Franceschi


DOI: 10.2174/1574887115666200811105251



Most Accessed Articles



Benign Intracranial Lesions - Radiotherapy: An Overview of Treatment Options, Indications and Therapeutic Results

, 2020; 15(2): 93-121.

Vasileios Tzikoulis, Areti Gkantaifi, Filippo Alongi, Nikolaos Tsoukalas, Haytham Hamed Saraireh, Nikolaos Charalampakis, Georgios Tzikoulis, Emmanouil Andreou, Konstantinos Tsapakidis, Dimitrios Kardamakis, Konstantinos Tsanadis, George Kyrgias and Maria Tolia*


DOI: 10.2174/1574887114666191111100635


A Review on the Use of Reversal Agents of Direct Oral Anticogulant Drugs in Case of Gastrointestinal Bleeding

, 2020; 15(4): 309-320.

Veronica Ojetti*, Angela Saviano, Mattia Brigida, Luisa Saviano, Alessio Migneco and Francesco Franceschi


DOI: 10.2174/1574887115666200624193938


Gut Alterations in Septic Patients: A Biochemical Literature Review

, 2020; 15(4): 289-297.

Yaroslava Longhitano*, Christian Zanza, Duraiyah Thangathurai, Samanta Taurone, Daniela Kozel, Fabrizio Racca, Andrea Audo, Enrico Ravera, Alessio Migneco, Andrea Piccioni and Francesco Franceschi


DOI: 10.2174/1574887115666200811105251


Management of Immunotherapy Adverse Events in Oncological Patients: Anti-CTLA-4, Anti-PD-1/PD-L1

, 2020; 15(4): 339-346.

Mattia Brigida, Alessia Perricelli, Fausto Sposato, Maria Giovanna Spadafora, Angelo Pomillo and Milito Sisto*


DOI: 10.2174/1574887115666200622161418


Anatomy, Physiology and Pathophysiology of Haemorrhoids

, 2021; 16(1): 75-80.

Francesco Pata*, Alessandro Sgró, Francesco Ferrara, Vincenzo Vigorita, Gaetano Gallo and Gianluca Pellino


DOI: 10.2174/1574887115666200406115150



Clinical Management of Infectious Diarrhea

, 2020; 15(4): 298-308.

Valentina Siciliano*, Enrico Celestino Nista, Tommaso Rosà, Mattia Brigida and Francesco Franceschi


DOI: 10.2174/1574887115666200628144128


Bedside Cardiac Pocus in Emergency Setting: A Practice Review

, 2020; 15(4): 269-277.

Christian Zanza*, Yaroslava Longhitano, Marco Artico, Gianmaria Cammarota, Andrea Barbanera, Fabrizio Racca, Andrea Audo, Enrico Ravera, Alessio Migneco, Andrea Piccioni and Francesco Franceschi


DOI: 10.2174/1574887115666200802023306


Light Alcohol Drinking and the Risk of Cancer Development: A Controversial Relationship

, 2020; 15(3): 164-177.

Giuseppe G. Caprio, Desiree Picascia, Marcello Dallio*, Pietro P. Vitiello, Emilio F. Giunta, Vincenzo De Falco, Ludovico Abenavoli, Anna C. Procopio, Vincenzo Famiglietti, Erika Martinelli, Antonietta G. Gravina, Alessandro Federico, Fortunato Ciardiello, Carmelina Loguercio and Davide Ciardiello


DOI: 10.2174/1574887115666200628143015


Physical Activity and Body Mass Index in Relation to Infertility in Women

, 2020; 15(3): 199-204.

Chieko Kaneda, Yuji Kanejima, Masahiro Kitamura and Kazuhiro P. Izawa*


DOI: 10.2174/1574887115666200506091936


Prevention of COVID-19 Infection in the Medical Population: Possible Help from Anosmia?

, 2020; 15(3): 244-245.

Giuseppe Chiarella*, Raffaella Pizzolato, Donatella Malanga, Davide Pisani, Ludovico Abenavoli and Pasquale Viola


DOI: 10.2174/1574887115666200603152637


Management of Pleural Effusions in the Emergency Department

, 2020; 15(4): 258-268.

Maria Teresa Congedo*, Gian Maria Ferretti, Dania Nachira and Mariano Alberto Pennisi


DOI: 10.2174/1574887115666200624194457




Editor-in-Chief

graphic
Ludovico Abenavoli
University Magna Graecia
Catanzaro
(Italy)
Biography
View Full Editorial Board

COPE Compliant

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Journal History

Reviews on Recent Clinical Trials Journal was launched in 2006. Dr. Ludovico Abenavoli serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.01

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