Reviews on Recent Clinical Trials

ISSN (Print): 1574-8871
ISSN (Online): 1876-1038

Volume 17 , Issues 4, 2022

This journal supports open access

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Editorial Board


rrct Editor-in-Chief 3306 Ludovico Abenavoli Department of Health Sciences University Magna Graecia Catanzaro Italy

Ludovico Abenavoli is an Associate Professor of gastroenterology at the Department of Health Sciences, University “Magna Græcia”, Catanzaro (Italy). Since 2012, he is invited professor at the University of Batna (Algeria), since 2015, he is inviting professor at the University of Novi Sad (Serbia), and since 2016, he is an Associate Professor at the Faculty of Medicine, University “Iuliu Hatieganu” of Cluj-Napoca (Romania). Between 2012 and 2015, he was board member of University Gastroenterology Education Committee (UNIGASTRO), and between 2013 and 2017, he was board member of Italian Society of Gastroenterology and Digestive Endoscopy (S.I.G.E.). Ludovico Abenavoli is the author of 144 publications in peer-reviewed international Journals in the field of gastroenterology and hepatology. His main contributions include: the treatment of alcoholic and nonalcoholic liver diseases, the evaluation of health effects of Mediterranean diet, the epidemiology of liver diseases.

l.abenavoli@unicz.it
Associate Editors 3307 Guglielmo Borgia Department of Clinical Medicine and Surgery University of Naples Federico II Naples Italy

Degree in Medicine and Surgery obtained in July 1973. He has carried out and mainly carries out research in the field of acute and chronic viral hepatitis and of the Syndrome from Acquired Immunodeficiency, developing themes of epidemiology, ultrastructure, therapy and prevention ed. He is the author of about 280 publications in national journals and international. He is a member of the Corporate Commission for the Control of Hospital Infections and of the Commission for the Management of Clinical Risk. Member of the Editorial Board of The Open Pharmacology Journal, Reviews on Recent Clinical Trial and Current Medicinal Chemistry.

borgia@unina.it
3308 Changhai Ding Menzies Institute for Medical Research University of Tasmania Tasmania Australia

Dr Changhai Ding is a Professor at University of Tasmanian, Associate Director (International) of Menzies Institute for Medical Research, an Honorary Professor at the University of Sydney, and an Adjunct Professor at Monash University. He is currently a Professor at Southern Medical University, an Adjunct Professor and Director of Arthritis Research Institute at Anhui Medical University and a Guest Professor at Xi’an Jiaotong University and Shanghai University of TCM, China.

changhai.ding@utas.edu.au
3309 Edith Nutescu Department of Pharmacy Practice Department of Pharmacy Systems, Outcomes, and Policy University of Illinois Chicago IL United States

She is the Director of Center for Pharmacoepidemiology and Pharmacoeconomic Research and Associate Professor, Pharmacy Systems, Outcomes and Policy at University of Illinois Hospital & Health Sciences System. Dr. Nutescu's areas of interest and research include Health Services and Outcomes Research, Cardiovascular Thrombosis, Safety and Comparative Effectiveness of Antithrombotic Agents, Patient Centered Self-Care and Behavioral Interventions, Patient Reported Outcomes (Quality of Life), Effectiveness of Clinical Pharmacy Services and Interventions.

enutescu@uic.edu
Regional Editors Australia 3310 Jane Nikles School of Medicine The University of Queensland Salisbury Australia

Dr Jane Nikles is a registered medical practitioner who has conducted research at The University of Queensland in the field of N-of-1 trials for over 19 years. In 2006, she completed a PhD at The University of Queensland; her doctoral work focussed on the use of the N-of-1 trial methodology in clinical practice. She has regular interaction with hospitals and GP practices, both staff and patients. Her research interests lie in advancing the science of N-of-1 trials and exploring the many applications of N-of-1 trials to maximise patient health outcomes.

uqjnikle@uq.edu.au
EUROPE 3311 Grazyna Biala Department of Pharmacology and Pharmacodynamics Medical University of Lublin Lublin Poland

Prof. GRAŻYNA BIAŁA, Department of Pharmacology with Pharmacodynamics, Medical University of Lublin, Poland Education: Faculty of Pharmacy, Medical University, Lublin, Poland; Master’s degree (highest honor), Department of Biochemistry; Doctoral thesis in pharmacology (highest honor), Department of Pharmacodynamics; Habilitation thesis in Pharmacology (highest honor), idem; since 2010–Full Professor degree, now: the Head of the Chair and Department of Pharmacology and Pharmacodynamics; since 2012 – Vice-Dean of the Faculty of Pharmacy with Medical Analitics Division, Medical University of Lublin, Poland. Research subjects include psychopharmacology, pharmacotherapy and experimental pharmacology.

grazyna.biala@umlub.pl grazyna.biala@am.lublin.pl
3312 Mario Masarone Internal Medicine and Hepatology Unit University of Salerno Salerno Italy

Dr Mario Masarone, graduated in Medicine and Surgery at the Second University of Naples in 2004, is a MD specialized in Internal Medicine. He obtained a doctorate (Ph.D.) in Biotechnologies in 2015. Actually is applied as a Post-doc Researcher at the Department of Medicine and Surgery of the University of Salerno (Italy). He has published at the time about 30 paper within the fields of Internal and Emergency Medicine and Hepatology. He is member of the Italian Association for the Study of the Liver (AISF) and European Association for the Study of the Liver (EASL).

mario.masarone@gmail.com
NORTH AMERICA 3313 Luigi Boccuto College of Behavioral, Social and Health Sciences Clemson University School of Health Research Clemson SC United States

Dr. Boccuto is a clinical geneticist who trained for several years under Professor Neri in Rome with a focus on in hereditary cancer, overgrowth syndromes and intellectual disability (ID) syndromes. Dr. Boccuto is currently an assistant research scientist at the JC Self Research Institute of the Greenwood Genetic Center. His main projects are focused on the study of the genetic causes of autism, ID, and conditions with segmental or generalized overgrowth. He is also characterizing the metabolic profiles of cells from patients with autism, ID and overgrowth, as well as mental disorders such as schizophrenia, ADD/ADHD and Tourette syndrome.

lboccut@clemson.edu
3314 Pingfu Fu Department of Population and Quantitative Health Sciences Case Western Reserve University Cleveland Ohio United States

Dr Fu is an Associate Professor of Biostatistics at Case Western Reserve University. He has over 15 years of experience in medical research, especially in cancer research. He have received a broad training in mathematics, statistics/biostatistics and computer science in both China and United States. His primary interests include providing advice for researchers in terms of study design, best practice for estimation, diagnostics, and use of appropriate statistical methods to analyze the complex data from pre-clinical and clinical studies. His methodologic research interests are in the areas of survival analysis, study design, measurements with limits of detection, tree-based methods, problem of separation, copula models to estimate the correlation of bivariate failure times and evaluation of diagnostics and agreement. He teaches survival data analysis annually and mentors/advises graduate students in Biostatistics.

pxf16@case.edu pxf@bfox.epbi.cwru.edu
Section Editors 3315 Veronica Ojetti Department of Emergency Medicine Università Cattolica del Sacro Cuore Rome Italy

Veronica Ojetti is assistant professor in gastroenterology and emergency medicine at the “Università Cattolica del Sacro Cuore”, in Rome, Italy. She obtained a degree in medicine and surgery cum laude and a specialization in Gastroenterology cum laude at the "Università Cattolica del Sacro Cuore". She graduated as PhD in physiopatology of body district at the university of Torvergata, and from 2001 she works at the emergency department of the “Fondazione policlinico universitario A. Gemelli” in Rome. She has published more than 100 papers on high Impact Factor Journals, expecially on functional gastrointestinal disorders, HP infection, and more recently her studies are focusing on gut microbiota and its modulation throughout the use of probiotics.

Gastroenterology (internal medicine and clinical trials) veronica.ojetti@gmail.com
8070 Raffaele Serra Orcid Division of Vascular Surgery University Magna Graecia Catanzaro Italy 0000-0003-4477-7412 22941905700 https://pubmed.ncbi.nlm.nih.gov/?term=serra+raffaele+or+serra+r+catanzaro+or+serra+r+naples+or+serra+r+cosenza&sort=date https://scholar.google.com/citations?user=56xBZyEAAAAJ&hl=it&oi=ao Surgery rserra@unicz.it
Editorial Board Members 3321 Francesco Andreozzi Department of Medical and Surgical Sciences University Magna Graecia Catanzaro Italy

Francesco Andreozzi (MD, PhD) is trained clinician in Internal Medicine and researcher in molecular biology and genetics. Francesco Andreozzi is aggregate professor in Internal Medicine and chief of the Day Hospital Clinic at University “Magna Graecia” of Catanzaro, Italy. Since 1997, his research developed over dual problems of epidemic of type 2 diabetes and acceleration of atherosclerosis that accompanies diabetes overall. His scientific production mainly concerns study of molecular mechanisms of insulin secretion and action; IGF-1 signal transduction; genetics of insulin-resistance, type 2 diabetes, molecular mechanisms of insulin resistance, obesity, cardiovascular diseases, hypertension; endothelial dysfunction and cardiovascular disease; randomized controlled clinical trials.

andreozzif@unicz.it andreozzifr@gmail.com
3317 Leonardo Baiocchi Orcid Department of Internal Medicine University of Rome Tor Vergata Rome Italy 0000-0003-3672-4505 baiocchi@uniroma2.it 3320 Matteo Barabino Department of Surgery University of Milan Milan Italy

Matteo Barabino, MD, is a surgeon, belonging to HPB Unit in San Paolo Hospital, University of Milan, Italy, directed by Prof. Enrico Opocher. He is specialist in general surgery, and his main field of interest has always been HPB surgery. He had the privilege to improve his anatomical knowledge and surgical US guided skillness in 2009, as fellows to the Department of HPB of Red Cross Medical Hospital Tokyo, directed by Masatoshi Makuuchi. Moreover the expertise in hepato-biliary surgery improved over the course of time.

mbarabino2@gmail.com
3330 Vance Berger Biometry Research Group University of Maryland Baltimore MD United States

Dr. Vance Berger completed his PhD in statistics at Rutgers University in 1995, and then began working at the FDA. This is where he developed his research focus on biases and threats to the validity of medical studies, especially clinical trials. In 1999, Dr. Berger joined the NCI, and has remained ever since. In 2005, he published a book, "Selection Bias and Covariate Imbalances in Randomized Clinical Trials" (Wiley), and continues to work actively in the field of selection bias, allocation concealment, and randomization methods (as covered in this book), plus overall trial quality and robustness against unwarranted assumptions.

bergerv@mail.nih.gov vb78c@nih.gov
3323 Alfredo Budillon Department of Research Istituto Nazionale Tumori- IRCCS G. Pascale Napoli Italy

Dr. Budillon graduated in Medicine and passed the Specialty Certification in Oncology at University Federico II, Naples, Italy. He obtained the PhD in Oncology from University G. D’Annunzio of Chieti, Italy, and a Master degree in Health economy, Management and Bioethics. Dr. Budillon is the chief of Experimental Pharmacology, National Cancer Institute G. Pascale, Naples, Italy. He is also Adjunct Professor in Temple University’s College of Science and Technology, Philadelphia, PA, USA, and author of more that 130 publications and of a patent. He is currently Regional Editor of Recent Patents on Anti-Cancer Drug Discovery, published by Bentham Science.

a.budillon@istitutotumori.na.it abudillon64@gmail.com
3329 Antonio R. Buonomo Department of Clinical Medicine and Surgery Policlinico Universitary Hospital Naples Italy

Dr. Antonio Riccardo Buonomo is Temporary Assistant Professor in Infectious DIseases at University of Naples "Federico". His field interest are viral hepatitis and antibiotic therapy. He has published many papers principally investigating new antiviral drugs for hepatitis C and he is currently approaching the unsolved issue of infections as one of the worst complication of liver cirrhosis.

antonioriccardobuonomo@gmail.com
3331 Pero Cahn Department of Clinical Research Fundacion Huesped Buenos Aires Argentina

Pedro Cahn has been working in infectious diseases for the last 45 years and has been involved in the HIV/AIDS arena since 1982. He has served as Chief of Infectious Diseases at the Juan Fernandez Hospital, where he is now Senior Consultant. He is President of Fundación Huésped in Buenos Aires, the largest NGO in Argentina serving patients with and at risk of HIV/AIDS. Dr. Cahn is Professor of Infectious Diseases at the Buenos Aires University Medical School. He is also a Past-President of the International AIDS Society. He is also an external advisor for UNAIDS, the World Health Organization (WHO), the Pan-American Health Organization, UNITAID, Doctors without Borders, as well as a member of the antiretroviral guidelines panel both for WHO and a former member of the guidelines panel of the International Antiviral Society-USA. Dr. Cahn has published more than 190 peer-reviewed papers and book chapters.

pcahn@huesped.org.ar
3332 Raymond Cheung Department of Medicine The University of Hong Kong Pokfulam Hong Kong

Professor Raymond Cheung is Lee Man-Chiu Professor in Neuroscience, Professor of Neurology at Department of Medicine, The University of Hong Kong, and Director of Acute Stroke Services, Hong Kong West Cluster Hospitals. He is a Fellow of the Royal Colleges of Edinburgh, Glasgow and London, as well as the American Heart Association, American Stroke Association, American Academy of Medicine, European Stroke Organization, Royal Society of Medicine, Hong Kong College of Physicians and Hong Kong Academy of Medicine. He is Past President of both Hong Kong Neurological Society and Hong Kong Stroke Society. His research interests include cerebrovascular disease, advanced and functional neuroimaging, and neuroprotection. He has published 160 journal papers and 26 book chapters.

rtcheung@hkucc.hku.hk rtcheung@hku.hk
3326 Dragos Cretoiu Cellular and Molecular Biology and Histology 'Carol Davila' University of Medicine and Pharmacy Bucharest Romania

Dr. Dragos Cretoiu is affiliated with 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania. Dr. Cretoiu‘s fields of research are Health Sciences, Medicine, Endocrinology and Metabolism. Dr. Cretoiu has several international publications and have an h-index of 25. Dr. Cretoiu is Editorial advisory board member of Reviews on Recent Clinical Trials, published by Bentham Science Publishers.

dragos@cretoiu.ro
3318 Kusal K. Das Orcid Department of Physiology BLDE Vijayapur India

Kusal K Das is the Professor of Physiology and Director of Vascular Physiology and Medicine, BLDE (Deemed to be University), Vijayapur. Prof. Das was a Visiting Professor of Medicine (2014-2016) at University of Leeds, UK and Visiting Professor of Physiology at Tulane University, USA (2017-2019). He is also UNESCO/UNITWIN Professor and Coordinator for Environmental Health under UNESCO Chair (Life Sciences). His area of research is on experimental hypoxia and cell signaling mechanism during heavy metal induced stress and alteration of vascular integrity in both animal and human models. Currently he is working on the HIF-1-dependent responses to hypoxia along with calcium channel blockers linked to cardiovascular and cerebrovascular ischemia. He is the recipient of “Dr.Raja Ramanna State Scientist Award 2015” by Government of Karnataka, India and ‘ISCA Endowment Lecture and G.P.Chatterjee Memorial Award 2019’ by Minsitry of Science and Technology, Government of India. He is admitted in the Royal Society of Biology, UK as Fellow since January 1, 2018. (158 Words)

0000-0002-3641-2117 57207466629 E-8167-2011 kusaldas@yahoo.com research@bldeuniversity.ac.in, kusaldas@bldedu.ac.in
3333 Konstantin H. Dragnev Department of Hematology/Oncology Dartmouth-Hitchcock Medical Center Hanover NH United States

He is Professor of Medicine at Dartmouth-Hitchcock Medical Center, Hanover, NH, USA. Dr. Dragnev’s research and clinical interests focus on the prevention and treatment of lung cancer, especially through bidirectional translation from laboratory discoveries to mechanism-driven clinical trials. Before joining Dartmouth, Dr. Dragnev worked in the NCI Laboratory of Comparative Carcinogenesis studying the role of Cytochrome P-450 and other drug-metabolizing enzymes in chemical carcinogenesis. More recently, he has focused his research on cyclin D1 and its implications for lung cancer therapy and chemoprevention, as well as window-of-opportunity clinical trials in resectable lung cancer.

konstantin.h.dragnev@hitchcock.org
3334 Barabara Ensoli Higher Institute of Health National AIDS Center Rome Italy

Dr. Ensoli is the Director of the National AIDS Center (Istituto Superiore di Sanità, Rome, Italy). She spent more than 10 years at the NIH in USA, elucidating the mechanisms of HIV pathogenesis and AIDS-associated tumors. Her current interests include also development of HIV/AIDS preventative and therapeutic vaccines. She has coordinated several international and national research programs in Europe and Developing countries. She is a member of the of the ERC Scientific Council, EMBO, and has been Vice-President of the National AIDS Committee of the Italian Ministry of Health (2006 -2015). She has received several national and international awards and authored more than 300 publications and 7 patents.

barbara.ensoli@iss.it
3324 Alessandro Federico Department of Hepato-Gastroenterology School of Medicine University of Campania Luigi Vanvitelli Naples Italy

Professor Alessandro Federico is Associate Professor in Hepatology and Gastroenterology at the Medicine and Surgery Faculty of Second University of Naples (Italy). He holds a Ph.D. in Digestive and Nutritional Physiopathology from Second University of Naples and he is also Specialist in Gastroenterology and Digestive Endoscopy. The interest field of his research is the role of radical species and nitric oxide in chronic liver and gastrointestinal diseases and the role of food and nutrition in digestive pathology. Notably, Prof. Federico has published more than 140 scientific publications and is a named inventor of 1 issued patent.

alessandro.federico@unicampania.it alessandro.federico@unina2.it
3335 Ivan Gentile Department of Clinical Medicine and Surgery University of Naples "Federico II" Naples Italy

Dr. Ivan Gentile obtained a degree in medicine cum laude from the University of Naples (SUN) and a specialization in Infectious Diseases at the University of Naples "Federico II" with maximum marks (70/70 cum laude). Currently Dr. Gentile is Assistant Professor at University of Naples Federico II. He has published about 80 scientific publications with an overall Impact factor of about 200. The H-index of 22 (source Scopus). He is reviewer for several scientific journals and as a reviewer for the funding of research projects for UK Medical Research Council (MRC).

ivan.gentile@alice.it ivan.gentile@unina.it
3327 Alessandro Gozzetti Department of Medical, Surgical and Neuroscience Sciences Universita degli Studi di Siena Siena Italy

Dr Alessandro Gozzetti gained his medical degree in 1993 and hematology fellowship in 1997 from Bologna University, Italy. He completed a PhD in oncology in 2001. He worked as research fellow 3 years at University of Chicago at the Molecular Cytogenetic Cancer Center lab. He gained National Scientific Abilitation as Associate Professor in Hematology in 2013. He is actually staff physician at the Division of Hematology of University of Siena, Italy. Dr Gozzetti is Director of the Multiple Myeloma program , CLL program and Hairy cell program and Director of the Molecular Cytogenetic Lab. He published over 130 papers in peer -reviewed Journals.

gozzetti@unisi.it
3328 Cesare Gridelli Division of Medical Oncology San Giuseppe Moscati Hospital Avellino Italy

Cesare Gridelli, MD, is currently Chief of Division of Medical Oncology and Director of Department of Oncology/Hematology at the “S.G. Moscati” Hospital, Avellino (Italy. His areas of expertise are lung cancer and cancer in the elderly. He is President of the Italian Association of Thoracic Oncology (AIOT). Dr..). He is author or co-author of more then 750 papers, of which more then 370 extended papers published on international indexed journals , and several chapters of books. His papers have about 16.378 citations on international indexed journals. Dr. Gridelli has an h-index of 62.

cgridelli@libero.it
3336 Raouf A. Khalil Division of Vascular Surgery Brigham and Women's Hospital Boston MA United States

Dr. Raouf Khalil is an MD PhD who is very interested in scientific research. After graduating from Medical School at Cairo University, he received his Masters in Pharmacology from Assiut University, then completed his PhD in Vascular Pharmacology at the University of Miami. Following fellowship training in Vascular Physiology and Molecular Biology at Harvard Medical School, Dr. Khalil joined the faculty at the University of Mississippi Medical Center. He then moved back to Harvard where he is currently Associate Professor at Harvard Medical School and Principal Investigator at Vascular Surgery Research Laboratories at the Brigham and Women's Hospital, Boston, Massachusetts, USA. Dr. Khalil oversees two NIH-funded research projects, and serves on the editorial boards of over 10 journals and as a reviewer for over 140 journals.

raouf_khalil@hms.harvard.edu
3316 Simka Marian Orcid Department of Anatomy University of Opole Opole Poland

Dr. Marian Simka is a specialist in angiology and general surgery. He is an associate professor at the Department of Anatomy, University of Opole, Poland and an associate professor at the Department of Nursing, College of Applied Sciences in Ruda Śląska, Poland. He is the author of about 200 publications in the field of angiology, phlebology, wound healing, vascular surgery and interventional radiology. Dr. Simka's research focuses on pathophysiology, diagnostics and treatment of venous pathologies.

0000-0002-2891-6083 msimka@uni.opole.pl
3337 Maurie Markman Department of Medical Oncology University of Texas Houston TX United States

Dr. Markman is the Annabel Irion Centennial Professor of Psychology and Marketing at The University of Texas at Austin. He received his Ph.D. in 1992 from the University of Illinois and worked at Northwestern University and Columbia University before coming to The University of Texas at Austin in 1998. He has written over 125 scholarly works on topics in higher-level thinking including analogical reasoning, decision making, and motivation. Dr. Markman has extensive experience in executive education and consulting. Dr. Markman and several of his books, including Smart Thinking, Smart Change, and Brain Briefs (co-written with Dr. Bob Duke), have been featured on Dr. Phil and other programs.

maurie.markman@ctca-hope.com
3338 Ruby Meredith Department Radiation Oncology University of Alabama Tuscaloosa AL United States

Ruby F. Meredith, MD, PhD is a Professor of Radiation Oncology at the University of Alabama at Birmingham. She is former Director of Research in that department, and a Senior Scientist at the University of Alabama at Birmingham Comprehensive Cancer Center. Her career includes basic science investigations and involvement in the conduct of scores of clinical trials, including 50 for targeted radionuclide therapy. Her activities are reflected in publications, memberships of scientific associations and she has served on numerous committees. Among her honors and awards is selection for Best Doctor listings > 10 years. More details are at. http://www.uab.edu/medicine/radonc/en/faculty2/ruby-f-meredith-md-phd

rmeredith@uabmc.edu
3339 Simone Mocellin Department of Experimental Medicine and Immunotherapy University of Padova Padova Italy

Prof. Simone Mocellin obtained his MD degree at the University of Padova, where he specialized in General Surgery in 1998 and he's got a PhD doctorate in Surgical Oncology in 2002. For two years (1999-2001) he worked at the Surgery Branch of the National Cancer Institute of Bethesda (Maryland, USA). Currently he works as consultant surgeon at the Surgical Oncology branch of the Istituto Oncologico Veneto (IOV-IRCCS) of Padova, Italy. He is also professor of surgery at the Dept. Surgery Oncology and Gastroenterology of the University of Padova, Italy. He is the author of more than 160 articles published in peer-review international medical journals. His main interest is surgical oncology with special regard to the surgical treatment and translational research in the fields of cutaneous melanoma, soft tissue sarcomas and gastrointestinal cancers.

mocellins@hotmail.com simone.mocellin@iov.veneto.it
6902 Gianluca Pellino Orcid Department of Advanced Medical and Surgical Sciences University of Campania Luigi Vanvitelli Napoli Italy

Dr. Gianluca Pellino has an M.D. degree. He is Ph.D. in Translational Medicine. and serves as Lecturer in General Surgery at the Università della Campania "Luigi Vanvitelli", Naples, Italy . He has served as Colorectal Surgeon at the Unit of Colorectal Surgery of University Hospital "La Fe", Valencia, Spain, as 2017 European Coloproctology Fellow. Dr Pellino has studied medicine at the Medical University of Naples and graduated in 2008. Since 2019, he is Fellow of the Royal College of Surgeons of England (FRCS). He is a Fellow of the European Board of Surgery (FEBS) in coloproctology upon passing the exam of the European Board of Surgical Qualification (EBSQ-c) in 2018. He is former Regional Representative (Campania) of the Italian Society of Colorectal Surgery (SICCR) and former Website Committee Member of the European Society of Coloproctology (ESCP). His special interests are in inflammatory bowel diseases, colorectal cancer, and proctology, with particular emphasis on surgical treatment of these diseases and surgical training. He is the Reviewer of several journals, including the British Journal of Surgery, Colorectal Disease, BMJ, Techniques in Coloproctology, Updates in Surgery, European Journal of Gastroenterology and Hepatology, World Journal of Gastroenterology, Surgical Innovation, and Digestive Surgery. He also serves as Social Media Editor of Techniques in Coloproctology,and he is in the Editorial Board of World Journal of Gastroenterology and Gastroenterology Research & Practice and serves as an Associate Editor of BMC Surgery and Medicine. He has received the Editor Assistant Bursary 2019 of British Journal of Surgery

0000-0002-8322-6421 57214971249 gipe1984@gmail.com
3340 Ryszard Pluta National Institutes of Health Bethesda MD United States

I was born and educated in Warsaw, Poland where I obtained my medical, neurosurgical, doctoral degrees and postdoctoral award in the field of Neurosurgery from the Medical Research Center of Polish Academy of Sciences and the Jerzy and Krystyna Chorobski Fundation. In 1989 I joined the Surgical Neurology Branch, at the National Institute of Neurological Disorders and Stroke, NIH first as International Fogarty Fellow and next as the Senior Researcher and Clinical Associate. In 2010 I joined JAMA Editorial Board as the Fishbein Fellow. In 2009 our patent “Nitrite for vascular diseases” got the “Deal of Distinction” Award. In 2013 I retired from the NIH. I presented near 120 lectures at national and international conferences, over 80 invited lectures at the universities and conferences and published over 120 articles in the leading medical journals.

ryszardpluta@me.com
3341 Marshall R. Posner Division of Hematology/Medical Oncology Dana-Farber Cancer Institute Boston MA United States

Dr. Marshall Posner is Professor of Medicine, Medical Director of the Head and Neck Oncology Program, and Associate Director of the Center for Personalized Cancer Therapeutics at the Icahn School or Medicine at Mount Sinai, NY. He has published over 275 peer-reviewed basic laboratory and clinical studies and multiple reviews and abstracts. Dr. Posner has been the principal investigator on numerous clinical trials in head and neck cancer and has reported studies of immunotherapy in pemphigus, HIV, and nasopharynx cancer. He has a major interest in the immunobiology and therapeutics of Human Papillomavirus and oropharynx cancer.

marshall.posner@mssm.edu
3319 Masataka Sawaki Department of Breast Oncology Aichi Cancer Center Hospital Nagoya Japan

Masataka Sawaki MD., Ph D. is a surgeon, belonging to the department of breast oncology, Aichi Cancer Center, Nagoya Japan. He is specialist in breast surgery, and his main field of interest has always been Breast Oncology. He graduated Nagoya University School of Medicine in 1995, and received his Ph.D. in 2005 from Nagoya University, Nagoya, Japan.

m-sawaki@aichi-cc.jp
3322 Emidio Scarpellini Department of Biomedical Sciences Catholic University of Leuven Leuven Belgium

Emidio Scarpellini has been Assistant Professor in Internal Medicine at the Sapienza University of Rome, Rome, Italy. He has published 49 papers, many involving gut microbiota modulation and GERD, and was a Rome III Foundation research fellow in Leuven, Belgium in 2009. He graduated as Phd in Physiopathology of metabolism and nutrition in 2013 at Catholic University of Sacred Heart, Rome, Italy and, in Biomedical Sciences in 2014 at KULeuven, Leuven, Belgium. He is a member of the American Gastroenterological Association, the Italian Society of Gastroenterology, and was an investigator on several recent trials investigating new drugs potentially affecting gut microbiota (e.g. antibiotics, probiotics use in functional gastrointestinal disorders), refractory GERD symptoms and reflux pathophysiology.

scarpidio@gmail.com
3325 Davide Tassinari Director of the Oncologic and Hematologic Department of Rimini City Hospital Rimini Italy

He graduated in Medicine and Surgery at the University of the "Sacred Heart" of Rome in 1990; in 1994 he specialized in Medical Oncology at the University of Ferrara and in 2006 in Hematology at the University of Ancona, always with honors. After obtaining a scholarship from the "Sant'Anna" Hospital in Ferrara, in 1992 Dr. Tassinari is a member of the Regional Medicines Commission, the Regional Cancer Medicines Group (GReFO), Regional Cancer Commission, the Therapeutic Committee of the Vasta Romagna Area, the Regional Coordination Group of the Palliative Care Network, and the "Hospital" Commission Territory Without Pain "by the .USL.“

dtassinari@rimini.com
3342 Eddy Shih-Hsin Yang Department of Radiation Oncology University of Alabama-Birmingham Birmingham AL United States

Eddy S. Yang, MD, PhD, received his MD and PhD from the University of Miami School of Medicine and continued post-graduate training in the Department of Radiation Oncology at Vanderbilt University as a Holman Pathway Resident Research Scholar. He subsequently joined the University of Alabama at Birmingham (UAB) in 2010 and is currently Professor and Vice Chair of Translational Sciences in the Department of Radiation Oncology. He also holds joint appointments in the departments of cell, developmental, and integrative biology as well as pharmacology and toxicology at UAB. Dr. Yang is the inaugural holder of the ROAR Southeast Cancer Foundation Endowed Chair and Director of the UAB Nanostring Laboratory.

eyang@uab.edu
Associate Editorial Board Member 3343 Imran Shahid Department of Pharmacology and Toxicology Umm Al-Qura University Makkah Saudi Arabia

Dr. Imran Shahid is an assistant Professor at Umm Al-Qura University, Makkah, Saudi Arabia where his research is focused on the broad areas of host-virus networks in HCV disease progression as well as host-virus genes expression during oxidative stress, hepatic steatosis, fibrosis, and hepatocellular carcinoma. He is also enthusiastically involved in the studies of HCV infection biology, Cell signaling pathways and genome heterogeneity in the Saudi population. He was trained from applied and functional genomics laboratory, National Centre of Excellence in Molecular Biology (NCEMB), University of the Punjab, Lahore, Pakistan where he worked on anti-mRNA based treatment strategies against hepatitis C virus 1a genotype in Pakistani population. Dr. Imran has published many research articles in peer-reviewed international journals and a member of the editorial board of several international journals.

iyshahid@uqu.edu.sa
Executive Guest Editors 3344 Gaetano Gallo Department of Medical and Surgical Sciences University Magna Graecia Catanzaro Italy

Gaetano Gallo is a Researcher at the Department of Medical and Surgical Sciences, University “Magna Græcia”, Catanzaro (Italy). In 2018 he completed a clinical training fellowship in IBD and colorectal tumors at the University of Amsterdam – Academic Medical Center. In 2016 and 2018 he has been awarded a fellowship by the Brazilian Society of Surgical Oncology (BSSO) and by the Japanese Society of Coloproctology (JSCP). His clinical and research interests include haemorrhoidal disease, rectovaginal and perianal fistula fistulas, minimally invasive treatment of pilonidal sinus (EPSiT), rectal prolapse, colorectal tumors and IBD as well as functional pelvic floor diseases. He has also a special interest in translational research (microRNA and microbiome).Since 2017, he is member of the Cohort Studies Committee of European Society of Coloproctology (ESCP) and Y-SICCR (Italian Society of Colorectal Surgery) Chair. Gaetano Gallo has published more than 50 articles in peer-reviewed journals in the field of Colorectal and General Surgery. Moreover, he is also reviewer for the most important european journals in the field of Colorectal Surgery and Proctology.

gaethedoctor@alice.it gaetanogallo1988@gmail.com, gaetanogallo1988@pec.it
6898 Christian Zanza Catholic University of Sacred Heart Rome Italy

Christian Zanza is a consultant in Anesthesia-Critical Care Medicine and consultant in Emergency- Internal Medicine in two hospitals: 1-Department of Anesthesia and Intensive Care, St. Antonio and Cesare Arrigo Teaching Hospital, Alessandria (Italy); 2- “Foundation of New Hospital Michele and Pietro Ferrero”. During the residency program in Anesthesia and Critical Care Medicine, he was Critical Care Fellow in London at St.George’s University Hospital for one year and during the second residency in Emergency Medicine, he was an assistant professor in Los Angeles for two years at the Department of Anesthesiology, University of Southern California. In 2017 he was awarded PhD in Clinical Pharmacology and Toxicology at the Sapienza University of Rome where he studied many aspects of the interaction between anaesthesia drugs. Christian Zaza is the author of many publications in peer-reviewed international Journals. His main contributions are focused on: invasive and non-invasive ventilation, treatment of acute severe cardiac diseases, biological markers of cardiac impairment and sepsis, use of POCUS in emergency settings.

christian.zanza@live.it
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