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Current Pharmaceutical Design

Volume 26, 46 Issues, 2020
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

,

Volume 26

-

Number 40



Editorial   Open Access



Review Article

Treatment of Anderson-Fabry Disease

, 26(40): 5089 - 5099

Irene Simonetta*, Antonino Tuttolomondo, Mario Daidone, Salvatore Miceli and Antonio Pinto


DOI: 10.2174/1381612826666200317142412


Review Article

Therapeutic Options for Mucopolysaccharidosis II (Hunter Disease)

, 26(40): 5100 - 5109

Francyne Kubaski, Filippo Vairo, Guilherme Baldo, Fabiano de Oliveira Poswar, Amauri Dalla Corte and Roberto Giugliani*


DOI: 10.2174/1381612826666200724161504


Review Article



General Review Article

Advancements in Polymer and Lipid-based Nanotherapeutics for Cancer Drug Targeting

, 26(40): 5119 - 5127

Mohammed Asadullah Jahangir, Mohamad Taleuzzaman*, Chandra Kala and Sadaf Jamal Gilani


DOI: 10.2174/1381612826999200820173253


General Review Article



General Review Article

Gold Nanoparticles- Boon in Cancer Theranostics

, 26(40): 5134 - 5151

Mehak Jindal, Manju Nagpal*, Manjinder Singh, Geeta Aggarwal and Gitika Arora Dhingra


DOI: 10.2174/1381612826666200701151403


General Review Article



Current Pharmaceutical Design, Volume 26 (2020) - Number 41


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print





Naphthoquinones and Derivatives for Chemotherapy: Perspectives and Limitations of their Anti-trypanosomatids Activities


Luíza Dantas-Pereira, Edézio F. Cunha-Junior, Valter V. Andrade-Neto, John F. Bower, Guilherme A. M. Jardim, Eufrânio N. da Silva Júnior, Eduardo C. Torres-Santos and Rubem F. S. Menna-Barreto*


DOI: 10.2174/1381612826666201109111802
View Abstract View on PubMed


Novel Antidiabetic Agents: Cardiovascular and Safety Outcomes


Gerasimos Siasos*, Evanthia Bletsa, Panagiota K. Stampouloglou, Stavroula A. Paschou, Evangelos Oikonomou, Vasiliki Tsigkou, Alexios S. Antonopoulos, Manolis Vavouranakis and Dimitrios Tousoulis


DOI: 10.2174/1381612826666201109110107
View Abstract View on PubMed




Stem Cell Based Preclinical Drug Development and Toxicity Prediction


Dhruv Kumar*, Prakash Baligar, Rajpal Srivastav, Priyanka Narad, Sibi Raj, Chanderdeep Tandon and Simran Tandon


DOI: 10.2174/1381612826666201019104712
View Abstract View on PubMed


Green Enabling Technologies for Competitive Synthesis of Pharmaceutical lead Compounds


Silvia Tagliapietra, Arianna Binello, Fabio Bucciol, Vladimir Trukhan, Mariachiara Colia and Giancarlo Cravotto*


DOI: 10.2174/1381612826999201116163951
View Abstract View on PubMed


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Therapeutic Options for Mucopolysaccharidosis II (Hunter Disease)

, 2020; 26(40): 5100 - 5109

Francyne Kubaski, Filippo Vairo, Guilherme Baldo, Fabiano de Oliveira Poswar, Amauri Dalla Corte and Roberto Giugliani*


DOI: 10.2174/1381612826666200724161504




Catechins as Model Bioactive Compounds for Biomedical Applications

, 2020; 26(33): 4032 - 4047

Adriana N. dos Santos, Tatiana R. de L. Nascimento, Brenna L. C. Gondim, Marilia M. A. C. Velo, Renaly I. de A. Rêgo, José R. do C. Neto, Juliana R. Machado, Marcos V. da Silva, Helvia W. C. de Araújo, Maria G. Fonseca and Lúcio R. C. Castellano*


DOI: 10.2174/1381612826666200603124418




Precision Medicine Approach in Prostate Cancer

, 2020; 26(31): 3783 - 3798

Majid Assadi, Narges Jokar, Mojtaba Ghasemi, Iraj Nabipour, Ali Gholamrezanezhad and Hojjat Ahmadzadehfar*


DOI: 10.2174/1381612826666200218104921






Intranasal Lipid Particulate Drug Delivery Systems: An Update on Clinical Challenges and Biodistribution Studies of Cerebroactive Drugs in Alzheimer’s disease

, 2020; 26(27): 3281 - 3299

Deepshi Arora, Shailendra Bhatt , Manish Kumar, Hari D.C. Vattikonda, Yugam Taneja, Vishal Jain, Veenu Joshi and Chaitanya C. Gali*


DOI: 10.2174/1381612826666200331085854




Open Access Articles


γ-Aminobutyric Acid and Derivatives Reduce the Incidence of Acute Pain after Herpes Zoster - A Systematic Review and Meta-analysis

, 2020; 26(25): 3026 - 3038

Wuttapon Sadaeng, Katalin Márta, Péter Mátrai, Péter Hegyi, Barbara Tóth, Balázs Németh, László M. Czumbel, Thanyaporn Sang-Ngoen, Zoltán Gyöngyi, Gábor Varga*, Péter Révész, István Szanyi, Kázmér Karádi and Gábor Gerber




Effects of Chlorine Dioxide on Oral Hygiene - A Systematic Review and Meta-analysis

, 2020; 26(25): 3015 - 3025

Beáta Kerémi, Katalin Márta, Kornélia Farkas, László M. Czumbel, Barbara Tóth, Zsolt Szakács, Dezső Csupor, József Czimmer, Zoltán Rumbus, Péter Révész, Adrienn Németh, Gábor Gerber, Péter Hegyi and Gábor Varga*




Vaccinium myrtillus L. Fruits as a Novel Source of Phenolic Compounds with Health Benefits and Industrial Applications - A Review

, 2020; 26(16): 1917 - 1928

Tânia C. S. P. Pires , Cristina Caleja , Celestino Santos-Buelga , Lillian Barros* and Isabel C.F.R. Ferreira*






Circulating MicroRNAs and Blood-Brain-Barrier Function in Breast Cancer Metastasis

, 2020; 26(13): 1417 - 1427

Carolin J. Curtaz, Constanze Schmitt, Kinga G. Blecharz-Lang, Norbert Roewer, Achim Wöckel and Malgorzata Burek*




Role of microRNA and Long Non-Coding RNA in Hepatocellular Carcinoma

, 2020; 26(4): 415 - 428

Meenakshi Gupta, Kumari Chandan and Maryam Sarwat*




Burden and Prevention of HPV. Knowledge, Practices and Attitude Assessment Among Pre-Adolescents and their Parents in Italy

, 2020; 26(3): 326 - 342

Giancarlo Icardi, Claudio Costantino, Marcello Guido, Antonella Zizza, Vincenzo Restivo, Daniela Amicizia, Federico Tassinari, Maria Francesca Piazza, Chiara Paganino, Alessandra Casuccio, Francesco Vitale, Filippo Ansaldi and Cecilia Trucchi*




Specificity and Continuity of Schizophrenia and Bipolar Disorder: Relation to Biomarkers

, 2020; 26(2): 191 - 200

Yuji Yamada, Madoka Matsumoto, Kazuki Iijima and Tomiki Sumiyoshi*




RHPN1-AS1 Drives the Progression of Hepatocellular Carcinoma via Regulating miR-596/IGF2BP2 Axis

, 2019; 25(43): 4630 - 4640

Hu Fen, Zheng Hongmin, Wei Wei, Yang Chao, Yao Yang, Liu Bei and Sun Zhihua*




Probucol-induced hERG Channel Reduction can be Rescued by Matrine and Oxymatrine in vitro

, 2019; 25(43): 4606 - 4612

Yuan-Qi Shi, Pan Fan, Guo-Cui Zhang, Yu-Hao Zhang, Ming-Zhu Li, Fang Wang and Bao-Xin Li*





Nanomedicines to Treat Skin Pathologies with Natural Molecules

, 2019; 25(21): 2323 - 2337

Elisabetta Esposito*, Claudio Nastruzzi, Maddalena Sguizzato and Rita Cortesi




The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity

, 2019; 25(19): 2192 - 2198

Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*





Most Cited Articles

General Review Article

Long non-coding RNAs as epigenetic regulators in cancer

, 2019; 25(33): 3563-3577.

Asma Vafadar, Zahra Shabaninejad, Ahmad Movahedpour, Soheila Mohammadi, Sima Fathullahzadeh, Hamid R. Mirzaei, Afshin Namdar, Amir Savardashtaki* and Hamed Mirzaei*


DOI: 10.2174/1381612825666190830161528


Review Article

Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning

, 2019; 25(33): 3519-3535.

Md. Tanvir Kabir, Md. Sahab Uddin*, Mst. Marium Begum, Shanmugam Thangapandiyan, Md. Sohanur Rahman, Lotfi Aleya, Bijo Mathew, Muniruddin Ahmed, George E. Barreto and Ghulam Md. Ashraf


DOI: 10.2174/1381612825666191008103141


Review Article

NMDA receptor antagonists: Repositioning of memantine as a multitargeting agent for Alzheimer's therapy

, 2019; 25(33): 3506-3518.

Md. Tanvir Kabir, Mohammad A. Sufian, Md. Sahab Uddin*, Mst. Marium Begum, Shammi Akhter, Ariful Islam, Bijo Mathew, Md. Siddiqul Islam, Md. Shah Amran and Ghulam Md. Ashraf*


DOI: 10.2174/1381612825666191011102444


Review Article

Synthesis of silver nanoparticles and their biomedical applications a comprehensive review

, 2019; 25(24): 2650-2660.

Rajasree Shanmuganathan, Indira Karuppusamy, Muthupandian Saravanan, Harshiny Muthukumar, Kumar Ponnuchamy, Vijayan Sri Ramkumar and Arivalagan Pugazhendhi*


DOI: 10.2174/1381612825666190708185506


Review Article

Emerging potential of naturally occurring autophagy modulators against neurodegeneration

, 2020; 26(7): 772-779.

Md. Ataur Rahman*, Md Rezanur Rahman, Toyfiquz Zaman, Md. Sahab Uddin, Rokibul Islam, Mohamed M. Abdel-Daim and Hyewhon Rhim*


DOI: 10.2174/1381612826666200107142541


Review Article

Alginate nanoparticles for drug delivery and targeting

, 2019; 25(11): 1312-1334.

Patricia Severino, Classius F. da Silva, Luciana N. Andrade, Daniele de Lima Oliveira, Joana Campos and Eliana B. Souto*


DOI: 10.2174/1381612825666190425163424



Review Article

Expression profile of MicroRNA: An emerging hallmark of cancer

, 2019; 25(6): 642-653.

Uzma Zaheer, Muhammed Faheem, Ishtiaq Qadri, Nargis Begum, Hadi M. Yassine, Asmaa A. Al Thani and Shilu Mathew*


DOI: 10.2174/1386207322666190325122821




Review Article

Metal/metal oxide nanoparticles: Toxicity, applications, and future prospects

, 2019; 25(37): 4013-4029.

Ratiram G. Chaudhary*, Ganesh S. Bhusari, Ashish D. Tiple, Alok R. Rai, Subhash R. Somkuvar, Ajay K. Potbhare, Trimurti L. Lambat, Prashant P. Ingle and Ahmed A. Abdala*


DOI: 10.2174/1381612825666191111091326



Review Article

Emerging strategies in stimuli-responsive nanocarriers as the drug delivery system for enhanced cancer therapy

, 2019; 25(24): 2609-2625.

Kandasamy Saravanakumar, Xiaowen Hu, Davoodbasha M. Ali and Myeong-Hyeon Wang*


DOI: 10.2174/1381612825666190709221141





Most Accessed Articles

Signaling Pathways in Inflammation and Anti-inflammatory Therapies

, 2018; 24(14): 1449-1484.

Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*


DOI: 10.2174/1381612824666180327165604


The Clinical Applications of Curcumin: Current State and the Future

, 2013; 19(11): 2011-2031.

Xia Fan, Chun Zhang, Dong-bo Liu, Jun Yan and Hua-ping Liang


DOI: 10.2174/1381612811319110005


Histone Modifications, Stem Cells and Prostate Cancer

, 2014; 20(11): 1687-1697.

Francesco Crea, Pier-Luc Clermont, Antonello Mai and Cheryl D. Helgason


DOI: 10.2174/13816128113199990522


Colchicine Pharmacokinetics and Mechanism of Action

, 2018; 24(6): 659-663.

Christos Angelidis*, Zoi Kotsialou, Charalampos Kossyvakis, Agathi-Rosa Vrettou, Achilleas Zacharoulis, Fotios Kolokathis, Vasilios Kekeris and Georgios Giannopoulos


DOI: 10.2174/1381612824666180123110042


Therapeutic Potential of Agonists and Antagonists of A1, A2a, A2b and A3 Adenosine Receptors

, 2019; 25(26): 2892-2905.

Sumit Jamwal, Ashish Mittal, Puneet Kumar*, Dana M. Alhayani and Amal Al-Aboudi


DOI: 10.2174/1381612825666190716112319




The Therapeutic Target Hsp90 and Cancer Hallmarks

, 2013; 19(3): 347-365.

Yoshihiko Miyata, Hitoshi Nakamoto and Len Neckers


DOI: 10.2174/1381612811306030347



Epidemiology of Non-alcoholic Fatty Liver Disease in North America

, 2020; 26(10): 993-997.

Tamoore Arshad, Pegah Golabi, Linda Henry and Zobair M. Younossi*


DOI: 10.2174/1381612826666200303114934



Editor-in-Chief

Alessandro Antonelli
Laboratory of Primary Human Cells
University of Pisa
Pisa
(Italy)
Biography
View Full Editorial Board

Executive Editor

Atta-ur-Rahman, FRS
(32052 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
(UK)
Biography

Nobel Laureate on Editorial Board

Andrew V. Schally
(USA)

Journal History

Current Pharmaceutical Design was introduced in 1995 with the assistance of Dr. William A. Banks.
Scopus CiteScore Metrics: 2.32

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