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Endorsements

"Current Pharmaceutical Design is a necessity for scientists working in the multidisciplinary fields encompassing the areas of drug design and discovery."

Annette M. Doherty
Pfizer Global R&D France

Forthcoming Special Issues

Recent advances towards the treatment of depressive disorders


Guest Editor(s): Kefeng Li, Xu Wang
Tentative Publication Date: June, 2018
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Special Issues - In-Press

Managing strategies for diverse diseases: Challenges from bench to bedside in successful drug discovery and development


Guest Editor(s): Mohammad Amjad Kamal, Nigel H. Greig
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Published Special Issues

Polypharmacology in drug discovery


Guest Editor(s): Luciana Scotti, Marcus T. Scotti
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Menglin Li
(School of Basic Medical Science, Beijing University of Chinese Medicine, Beijing 100029, China)


Current Pharmaceutical Design

,

Volume 24

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Number 3



Editorial   Open Access





Review Article

Inflammatory Arthritis and Heart Disease

, 24(3): 262 - 280

Santos Castaneda*, Carlos Gonzalez-Juanatey and Miguel A. Gonzalez-Gay*


DOI: 10.2174/1381612824666180123102632




Review Article





Review Article





Review Article





Review Article

Inflammation, Atrial Fibrillation and Cardiac Surgery: Current Medical and Invasive Approaches for the Treatment of Atrial Fibrillation

, 24(3): 310 - 322

Sahin Iscan*, Bortecin Eygi, Yuksel Besir, Ismail Yurekli, Habib Cakir, Levent Yilik, Orhan Gokalp and Ali Gurbuz


DOI: 10.2174/1381612824666180131120859




Review Article

Torsades de Pointes in Patients with Polymyalgia Rheumatica

, 24(3): 323 - 340

Pietro Enea Lazzerini*, Iacopo Bertolozzi, Maurizio Acampa, Rosella Fulceri, Franco Laghi-Pasini and Pier Leopoldo Capecchi


DOI: 10.2174/1381612824666180111111124




Review Article





Human Oral Defensins Antimicrobial Peptides: A Future Promising Antimicrobial Drug


Zohaib Khurshid, Muhammad S. Zafar*, Mustafa Naseem, Rabia Sannam Khan and Shariq Najeeb


View Abstract View on PubMed


The Potential Mechanisms of Exercise-induced Cognitive Protection: A Literature Review


Jennifer E. Norman*, Jennifer Rutkowsky, Sue Bodine and John C. Rutledge


View Abstract View on PubMed


Heterocyclic N-oxides - A Promising Class of Agents Against Tuberculosis, Malaria and Neglected Tropical Diseases


Guilherme Felipe dos Santos Fernandes, Aline Renata Pavan and Jean Leandro dos Santos*


View Abstract


Virtual screening studies for discovery of novel inhibitors of inflammatory process targets


Marcus Tullius Scotti*, Mateus Feitosa Alves, Chonny Alexander Herrera-Acevedo and Luciana Scotti


View Abstract


Comparative study of the effects exerted by N-Valproyl-L-Phenylalanine and N-valproyl-L-tryptophan on CA1 hippocampal epileptiform activity in rat


Fabio Carletti*, Valerio Rizzo, Giuditta Gambino, Viviana De Caro, Flavia Maria Sutera, Libero Italo Giannola, Giuseppe Ferraro and Pierangelo Sardo*


View Abstract


A Novel Fluorescence-Labeled Curcumin Conjugate: Synthesis, Evaluation And Imaging On Human Cell Lines


Sumbla Sheikh*, Alexander Sturzu , Hubert Kalbacher , Thomas Nagele, Christopher Weidenmaier , Marius Horger, Christian Schwentner , Ulrike Ernemann and Stefan Heckl


View Abstract


The effects of coenzyme Q10 supplementation on lipid profiles among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials


Nasrin Sharifi, Reza Tabrizi, Mahmood Moosazadeh, Naghmeh Mirhosseini, Kamran B Lankarani, Maryam Akbari, Maryam Chamani, Fariba Kolahdooz and Zatollah Asemi*


View Abstract


Comparative Assay of 2D and 3D Cell Culture Models: Proliferation, Gene Expression and Anticancer Drug Response.


Aline G. Souza*, Isaura Beatriz. B. Silva, Esther Campos-Fernandez, Leticia S. Barcelos, Jessica Brito Souza, Karina Marangoni, Luiz R. Goulart and Vivian Alonso-Goulart


View Abstract


Potential Use Of Nanomedicine For The Anti-Inflammatory Treatment Of Neurodegenerative Diseases


Maria Dolores Cayero-Otero, Ana M. Espinosa-Oliva*, Antonio J. Herrera, Irene Garcia-Dominguez, Mercedes Fernandez-Arevalo, Lucia Martin-Banderas and Rocio M. de Pablos


View Abstract


Management of antithrombotic therapy in patients with coronary artery disease or atrial fibrillation who underwent abdominal surgical operations


Dimitrios Schizas*, Maria Kariori, Konstantinos Dean Boudoulas, Gerasimos Siasos, Nikolaos Patelis, Charalampos Kalantzis , Moldovan Carmen-Maria and Manolis Vavuranakis


View Abstract


Curcumin as an Adjunct Therapy and microRNA Modulator in Breast Cancer

, 2018; 24(2): 171 - 177

Saeed Norouzi, Muhammed Majeed, Matteo Pirro, Daniele Generali and Amirhossein Sahebkar*


DOI: 10.2174/1381612824666171129203506



Statins and Oxidative Stress in the Cardiovascular System

, 2017; 23(46): 7040 - 7047

Marios Margaritis, Fabio Sanna and Charalambos Antoniades*


DOI: 10.2174/1381612823666170926130338



Intranasal Lipid Nanoparticles for the Treatment of Neurodegenerative Diseases

, 2017; 23(43): 6553 - 6562

S. Cunha, H. Almeida, M.H. Amaral*, J.M. Sousa Lobo and A.C. Silva*


DOI: 10.2174/1381612824666171128105305



Antiepileptics for Post-Traumatic Seizure Prophylaxis after Traumatic Brain Injury

, 2017; 23(42): 6428 - 6441

Alexander G. Chartrain, Kurt Yaeger, Rui Feng, Marios S. Themistocleous, Neha S. Dangayach, Konstantinos Margetis and Zachary L. Hickman*


DOI: 10.2174/1381612823666171031100139



Bone-Muscle Crosstalk: Unraveling New Therapeutic Targets for Osteoporosis

, 2017; 23(41): 6256 - 6263

Anna Picca, Riccardo Calvani*, Ester Manes-Gravina, Leonardo Spaziani, Francesco Landi, Roberto Bernabei and Emanuele Marzetti


DOI: 10.2174/1381612823666170526112300



Preterm Birth and Neonatal Injuries: Importance of Interleukin-1 and Potential of Interleukin-1 Receptor Antagonists

, 2017; 23(40): 6132 - 6141

Mathieu Nadeau-Vallee, Dima Obari, Alexandra Beaudry-Richard, Estefania Marin Sierra, Alexandre Beaulac, Noemie Maurice, David M. Olson* and Sylvain Chemtob*


DOI: 10.2174/1381612823666170825145114



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