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Current Pharmaceutical Design

Volume 25, 46 Issues, 2019
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

Ranking and Category

  • 148th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

,

Volume 25

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Number 34



Editorial   Open Access



Review Article

Application of Three-dimensional (3D) Tumor Cell Culture Systems and Mechanism of Drug Resistance

, 25(34): 3599 - 3607

Adeeb Shehzad, Vijaya Ravinayagam, Hamad AlRumaih, Meneerah Aljafary, Dana Almohazey, Sarah Almofty, Noor A. Al-Rashid and Ebtesam A. Al-Suhaimi*


DOI: 10.2174/1381612825666191014163923


Review Article

Biocompatible Polymers and their Potential Biomedical Applications: A Review

, 25(34): 3608 - 3619

Uzma Arif, Sajjad Haider, Adnan Haider*, Naeem Khan*, Abdulaziz A. Alghyamah, Nargis Jamila, Muhammad Imran Khan, Waheed A. Almasry and Inn-Kyu Kang


DOI: 10.2174/1381612825999191011105148


Review Article



Review Article



Review Article

Pollution, Toxicity and Carcinogenicity of Organic Dyes and their Catalytic Bio-Remediation

, 25(34): 3645 - 3663

Muhammad Ismail, Kalsoom Akhtar, M.I. Khan, Tahseen Kamal, Murad A. Khan, Abdullah M. Asiri, Jongchul Seo and Sher B. Khan*


DOI: 10.2174/1381612825666191021142026


Research Article



Research Article

Preparation and Characterization of Agar Based Magnetic Nanocomposite for Potential Biomedical Applications

, 25(34): 3672 - 3680

Nasrullah Shah*, Tahir Zaman, Touseef Rehan, Salman Khan, Waliullah Khan, Abbas Khan and Mazhar Ul-Islam*


DOI: 10.2174/1381612825666191011113109


Articles Ahead of Print

Circulating miRNAs in Successful and Unsuccessful Aging. A Mini-review


Giuseppe Cammarata, Giovanni Duro*, Tiziana Di Chiara, Alessia Lo Curto, Simona Taverna and Giuseppina Candore


DOI: 10.2174/1381612825666191119091644
View Abstract View on PubMed



Exosomes in Sepsis and Inflammatory Tissue Injury


Eun Jeong Park*, Michael G. Appiah, Phyoe Kyawe Myint, Arong Gaowa, Eiji Kawamoto and Motomu Shimaoka*


DOI: 10.2174/1381612825666191116125525
View Abstract View on PubMed



Neurotoxic and Neuroprotective Role of Exosomes in Parkinson’s Disease


Biancamaria Longoni, Irene Fasciani, Shivakumar Kolachalam, Ilaria Pietrantoni, Francesco Marampon, Francesco Petragnano, Gabriella Aloisi, Maria F. Coppolino, Mario Rossi, Marco Scarselli and Roberto Maggio*


DOI: 10.2174/1381612825666191113103537
View Abstract View on PubMed


Wnt-β-catenin Signaling Pathway, the Achilles' Heels of Cancer Multidrug Resistance


Morteza Ghandadi*, Reza Valadan, Hamidreza Mohammadi, Javad Akhtari, Shaban Ali Khodashenas and Sorour Ashari


DOI: 10.2174/1381612825666191112142943
View Abstract View on PubMed




Effects of Aging and Diet on Cardioprotection and Cardiometabolic Risk Markers


Andreea Corina, Maria Bianca Abrudan, Dragana Nikolic*, Adriana Florinela Cӑtoi, Roberta Chianetta, Giuseppa Castellino, Roberto Citarrella, Anca Pantea Stoian, Pablo Pérez-Martínez and Manfredi Rizzo


DOI: 10.2174/1381612825666191105111232
View Abstract View on PubMed


Risk Factors of Recurrent Ischemic Events after Acute Noncardiogenic Ischemic Stroke


Limin Zhang, Xingang Li, Dongzhi Wang, Hong Lv, Xuezhong Si, Xiao Li, Yuehong Sun, Dan Wang, Kelin Chen, Xixiong Kang, Xin Lou, Guojun Zhang and Ning Ma*


DOI: 10.2174/1381612825666191029103756
View Abstract View on PubMed


Abstracts Ahead of Print



Neurodegenerative diseases associated with mitochondrial DNA mutations


Olga A. Zhunina, Nikita G. Yabbarov, Andrey V. Grechko, Shaw-Fang Yet, Igor A. Sobenin and Alexander N. Orekhov*


DOI: 10.2174/1381612825666191122091320
View Abstract



Advances in the Detection, Mechanism and Therapy of Chronic Kidney Disease


Yu Dong, Xiaosheng Qu, Gang Wu, Xiangdong Luo, Botao Tang, Fangfang Wu, Lanlan Fan, Sooranna Dev and Taisheng Liang*


DOI: 10.2174/1381612825666191119094354
View Abstract





Published Contents

Editor's Choice

Application of Three-dimensional (3D) Tumor Cell Culture Systems and Mechanism of Drug Resistance

, 2019; 25(34): 3599 - 3607

Adeeb Shehzad, Vijaya Ravinayagam, Hamad AlRumaih, Meneerah Aljafary, Dana Almohazey, Sarah Almofty, Noor A. Al-Rashid and Ebtesam A. Al-Suhaimi*


DOI: 10.2174/1381612825666191014163923






TREX1 As a Potential Therapeutic Target for Autoimmune and Inflammatory Diseases

, 2019; 25(30): 3239 - 3247

Sha-Sha Tao*, Guo-Cui Wu, Qin Zhang, Tian-Ping Zhang, Rui-Xue Leng, Hai-Feng Pan and Dong-Qing Ye


DOI: 10.2174/1381612825666190902113218



A Mitochondrial Approach to Cardiovascular Risk and Disease

, 2019; 25(29): 3175 - 3194

Caroline D. Veloso, Getachew D. Belew, Luciana L. Ferreira, Luís F. Grilo, John G. Jones, Piero Portincasa, Vilma A. Sardão and Paulo J. Oliveira*


DOI: 10.2174/1389203720666190830163735




Hyperferritinaemia: An Iron Sword of Autoimmunity

, 2019; 25(27): 2909 - 2918

Joanna Giemza-Stokłosa, Md. Asiful Islam and Przemysław J. Kotyla*


DOI: 10.2174/1381612825666190709202804



Adenosine Receptors in Modulation of Central Nervous System Disorders

, 2019; 25(26): 2808 - 2827

Hira Choudhury, Dinesh K. Chellappan, Pallav Sengupta, Manisha Pandey and Bapi Gorain*


DOI: 10.2174/1381612825666190712181955




Open Access Articles

Nanomedicines to Treat Skin Pathologies with Natural Molecules

, 2019; 25(21): 2323 - 2337

Elisabetta Esposito*, Claudio Nastruzzi, Maddalena Sguizzato and Rita Cortesi




The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity

, 2019; 25(19): 2192 - 2198

Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*






Effects of As2O3 and Resveratrol on the Proliferation and Apoptosis of Colon Cancer Cells and the hERG-mediated Potential Mechanisms

, 2019; 25(12): 1385 - 1391

Caichuan Yan*, Fengmei Li*, Yuhao Zhang, Yang Li, Mingzhu Li, Fang Wang, Guocui Zhang, Yuexin Li, Baoxin Li and Xin Zhao







Small Molecules as PD-1/PD-L1 Pathway Modulators for Cancer Immunotherapy

, 2018; 24(41): 4911 - 4920

Peifu Jiao, Qiaohong Geng*, Peng Jin, Gaoxing Su, Houyun Teng, Jinlong Dong and Bing Yan*





Novel Data on the Prevalence, Identification, Scouting, and Treatment of Familial Hypercholesterolaemia

, 2018; 24(31): 3597 - 3598

Michael Doumas, Konstantinos Imprialos, Konstantinos Stavropoulos and Vasilios G. Athyros





Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis

, 2018; 24(26): 3143 - 3151

Alexander N. Orekhov*, Yumiko Oishi , Nikita G. Nikiforov, Andrey V. Zhelankin, Larisa Dubrovsky, Igor A. Sobenin, Alexander Kel, Daria Stelmashenko, Vsevolod J. Makeev, Kathy Foxx, Xueting Jin, Howard S. Kruth and Michael Bukrinsky




Novel Technologies for Dipeptide Drugs Design and their Implantation

, 2018; 24(26): 3020 - 3027

Tatiana A. Gudasheva*, Rita U. Ostrovskaya and Sergey B. Seredenin




Coronary Microcirculation in Ischemic Heart Disease

, 2018; 24(25): 2893 - 2899

Axel R. Pries*, Wolfgang M. Kuebler and Helmut Habazettl





Most Cited Articles


Research Article

PNitro-Tyr-PseAAC: Predict nitrotyrosine sites in proteins by incorporating five features into Chou’s general PseAAC

, 2018; 24(34): 4034-4043.

Ahmad W. Ghauri, Yaser D. Khan, Nouman Rasool, Sher A. Khan* and Kuo-Chen Chou


DOI: 10.2174/1381612825666181127101039


Review Article

Rapid-acting antidepressants

, 2018; 24(22): 2556-2563.

Jeffrey M. Witkin*, Daniel E. Knutson, Gabriel J. Rodriguez and Samuel Shi


DOI: 10.2174/1381612824666180730104707


Review Article

Antibacterial metal oxide nanoparticles: Challenges in interpreting the literature

, 2018; 24(8): 896-903.

Usha Kadiyala, Nicholas A. Kotov and J. Scott VanEpps*


DOI: 10.2174/1381612824666180219130659


Review Article

Signaling pathways in inflammation and anti-inflammatory therapies

, 2018; 24(14): 1449-1484.

Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*


DOI: 10.2174/1381612824666180327165604


Review Article

Polyphenols: Potential use in the prevention and treatment of cardiovascular diseases

, 1 January 2018; 24(2): 239-258.

Rosaria Vincenza Giglio, Angelo Maria Patti, Arrigo F.G. Cicero, Giuseppe Lippi, Manfredi Rizzo*, Peter P. Toth and Maciej Banach


DOI: 10.2174/1381612824666180130112652


Review Article

Curcumin: A natural pan-HDAC inhibitor in cancer

, 1 January 2018; 24(2): 123-129.

Sara Saffar Soflaei, Amir Abbas Momtazi-Borojeni, Muhammed Majeed, Giuseppe Derosa, Pamela Maffioli and Amirhossein Sahebkar*


DOI: 10.2174/1381612823666171114165051


Review Article

Colchicine pharmacokinetics and mechanism of action

, 2018; 24(6): 659-663.

Christos Angelidis*, Zoi Kotsialou, Charalampos Kossyvakis, Agathi-Rosa Vrettou, Achilleas Zacharoulis, Fotios Kolokathis, Vasilios Kekeris and Georgios Giannopoulos


DOI: 10.2174/1381612824666180123110042


Review Article

Recent findings in molecular basis of inflammation and anti-inflammatory plants

, 2018; 24(14): 1551-1562.

Sedigheh Kazemi, Hedayatollah Shirzad and Mahmoud Rafieian-Kopaei*


DOI: 10.2174/1381612824666180403122003


Review Article

Curcumin as an adjunct therapy and microRNA modulator in breast cancer

, 1 January 2018; 24(2): 171-177.

Saeed Norouzi, Muhammed Majeed, Matteo Pirro, Daniele Generali and Amirhossein Sahebkar*


DOI: 10.2174/1381612824666171129203506


Review Article

Antibacterial coatings based on chitosan for pharmaceutical and biomedical applications

, 2018; 24(8): 866-885.

Juliana Miguel Vaz, Daniele Pezzoli, Pascale Chevallier, Clayton Souza Campelo, Gabriele Candiani and Diego Mantovani*


DOI: 10.2174/1381612824666180219143900


Review Article

Placental exosomes during gestation: Liquid biopsies carrying signals for the regulation of human parturition

, 2018; 24(9): 974-982.

Carlos Salomon*, Zarin Nuzhat, Christopher L. Dixon and Ramkumar Menon*


DOI: 10.2174/1381612824666180125164429


Review Article

Cytoprotective polyphenols against chronological skin aging and cutaneous photodamage

, 1 January 2018; 24(2): 99-105.

Sergio Davinelli*, Juan Carlos Bertoglio, Ascanio Polimeni and Giovanni Scapagnini


DOI: 10.2174/1381612823666171109102426


Review Article

Simulated protein thermal detection (SPTD) for enzyme thermostability study and an application example for pullulanase from bacillus deramificans

, 2018; 24(34): 4023-4033.

Jian-Xiu Li, Shu-Qing Wang, Qi-Shi Du*, Hang Wei, Xiao-Ming Li, Jian-Zong Meng, Qing-Yan Wang, Neng-Zhong Xie*, Ri-Bo Huang* and Kuo-Chen Chou


DOI: 10.2174/1381612824666181113120948




Most Accessed Articles

Recent Advances in Cancer Therapy: An Overview

, 2010; 16(1): 3-10.

A. Urruticoechea, R. Alemany, J. Balart, A. Villanueva, F. Vinals and G. Capella


DOI: 10.2174/138161210789941847




The Transport Mechanism of Extracellular Vesicles at the Blood-Brain Barrier

, 2017; 23(40): 6206-6214.

Junichi Matsumoto, Tessandra Stewart, William A. Banks and Jing Zhang*


DOI: 10.2174/1381612823666170913164738


JAK Inhibition: The Most Promising Agents in the IBD Pipeline?

, 2019; 25(1): 32-40.

Agnès Fernández-Clotet, Jesús Castro-Poceiro and Julián Panés*


DOI: 10.2174/1381612825666190405141410


Inhibition of Heat Shock Protein 90 as a Novel Platform for the Treatment of Cancer

, 2019; 25(8): 849-855.

Chang Gao, Ya-Nan Peng, Hai-Zhou Wang, Shi-Lin Fang, Meng Zhang, Qiu Zhao and Jing Liu*


DOI: 10.2174/1381612825666190503145944


The Microbial Quality Aspects and Decontamination Approaches for the Herbal Medicinal Plants and Products: An in-Depth Review

, 2016; 22(27): 4264-4287.

Daniela Dal Molim Ghisleni, Marina de Souza Braga, Irene Satiko Kikuchi, Mirela Braşoveanu, Monica R. Nemţanu, Kamal Dua and Terezinha de Jesus Andreoli Pinto


DOI: 10.2174/1381612822666160623070829






Editor-in-Chief

William A. Banks
(29546 citations)
Seattle VA Puget Sound Health Care System
Room 810C, Building 1
1660 S. Columbian Way
Seattle, WA 98108
USA

Biography View Full Editorial Board

Journal History

Current Pharmaceutical Design was introduced in 1995 with the assistance of Dr. William A. Banks, who is the current Editor-in-Chief serving since 1995.
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Scopus CiteScore Metrics: 1.94

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