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Current Pharmaceutical Design

Volume 25, 46 Issues, 2019
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

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  • 148th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

,

Volume 25

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Number 19



Editorial   Open Access



Review Article



Review Article

Multimodal Analgesia for Perioperative Management of Patients presenting for Spinal Surgery

, 25(19): 2123 - 2132

Deepak Agarwal*, Praveen Chahar, Mark Chmiela, Afrin Sagir, Arnold Kim, Faysal Malik and Ehab Farag


DOI: 10.2174/1381612825666190708174639


Review Article



Review Article



Review Article



Review Article



Review Article

Anaesthesia for the Growing Brain

, 25(19): 2165 - 2170

Divya Raviraj*, Thomas Engelhardt and Tom G. Hansen


DOI: 10.2174/1381612825666190702151030


Current Pharmaceutical Design, Volume 25 (2019) - Number 23


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 25 (2019) - Number 22


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 25 (2019) - Number 21


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 25 (2019) - Number 20


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Colorectal Adenocarcinoma: Imaging using 5-Fluoracil Nanoparticles Labeled with Technetium 99 Metastable


Julio Cesar de Almeida, Edward Helal-Neto, Suyene Rocha Pinto, Sofia Nascimento Dos Santos, Emerson Soares Bernardes, Mohammed Al-Qahtani, Fiammetta Nigro, Luciana Magalhaes Rebelo Alencar, Eduardo Ricci-Junior and Ralph Santos-Oliveira*


DOI: 10.2174/1381612825666190816235147
View Abstract View on PubMed






Diabetes and Vascular Disease: Is It All About Glycemia?


Alessandra Vecchié, Fabrizio Montecucco, Federico Carbone, Franco Dallegri and Aldo Bonaventura*


DOI: 10.2174/1381612825666190830181944
View Abstract View on PubMed


Macrophage: A Key Therapeutic Target in Atherosclerosis?


Eskandar Taghizadeh*, Forough Taheri*, Pedram Ghorbani Renani, Željko Reiner, Jamshid Gholizadeh Navashenaq and Amirhossein Sahebkar*


DOI: 10.2174/1381612825666190830153056
View Abstract View on PubMed



The Effects of L-carnitine Supplementation on Serum Lipids: A Systematic Review and Meta-analysis of Randomized Controlled Trials


Hadis Fathizadeh, Alireza Milajerdi, Željko Reiner, Fariba Kolahdooz, Maryam Chamani, Elaheh Amiani and Zatollah Asemi*


DOI: 10.2174/1381612825666190830154336
View Abstract View on PubMed



Abstracts Ahead of Print

Nanoparticle Toxicity In Fish Models


Jimena Cazenave*, Analía Ale, Carla Bacchetta and Andrea Silvana Rossi


DOI: 10.2174/1381612825666190912165413
View Abstract





Next-Generation Sequencing: An emerging tool for Drug Designing


Pooja Tripathi, Jyotsna Singh, Jonathan A. Lal and Vijay Tripathi*


DOI: 10.2174/1381612825666190911155508
View Abstract


Insights into Structure-Function Relationships of β-Lactamase and BLIPs Interface Plasticity using Protein-Protein Interactions


Tara Chand Yadav, Vidhu Agarwal, Amit Kumar Srivastava, Navdeep Raghuwanshi, Pritish Varadwaj, Ramasare Prasad and Vikas Pruthi*


DOI: 10.2174/1381612825666190911154650
View Abstract


Hydroxyapatite-alginate based matrices for drug delivery


Amit Kumar Nayak, Md Saquib Hasnain, Sitansu Sekhar Nanda* and Dong Kee Yi*


DOI: 10.2174/1381612825666190906164003
View Abstract





Published Contents

Editor's Choice


Gut Microbiota, Obesity and Bariatric Surgery: Current Knowledge and Future Perspectives

, 2019; 25(18): 2038 - 2050

Adriana Florinela Cӑtoi, Dan Cristian Vodnar, Andreea Corina, Dragana Nikolic*, Roberto Citarrella, Pablo Pérez-Martínez and Manfredi Rizzo


DOI: 10.2174/1381612825666190708190437






Innovative Solutions for the Control of Leishmaniases: Nanoscale Drug Delivery Systems

, 2019; 25(14): 1582 - 1592

Victoria Wagner, Aida Minguez-Menendez, Joan Pena and Christopher Fernández-Prada*


DOI: 10.2174/1381612825666190621154552





Macroalgal Polysaccharides in Biomimetic Nanodelivery Systems

, 2019; 25(11): 1265 - 1289

Nikola Geskovski, Simona Dimchevska Sazdovska and Katerina Goracinova*


DOI: 10.2174/1381612825666190423155116



Potential Regulation Mechanisms of P-gp in the Blood-Brain Barrier in Hypoxia

, 2019; 25(10): 1041 - 1051

Yidan Ding, Rong Wang*, Jianchun Zhang, Anpeng Zhao, Hui Lu, Wenbin Li, Chang Wang and Xuechun Yuan


DOI: 10.2174/1381612825666190610140153



Open Access Articles

The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity

, 2019; 25(19): 2192 - 2198

Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*





Effects of As2O3 and Resveratrol on the Proliferation and Apoptosis of Colon Cancer Cells and the hERG-mediated Potential Mechanisms

, 2019; 25(12): 1385 - 1391

Caichuan Yan*, Fengmei Li*, Yuhao Zhang, Yang Li, Mingzhu Li, Fang Wang, Guocui Zhang, Yuexin Li, Baoxin Li and Xin Zhao






Small Molecules as PD-1/PD-L1 Pathway Modulators for Cancer Immunotherapy

, 2018; 24(41): 4911 - 4920

Peifu Jiao, Qiaohong Geng*, Peng Jin, Gaoxing Su, Houyun Teng, Jinlong Dong and Bing Yan*





Novel Data on the Prevalence, Identification, Scouting, and Treatment of Familial Hypercholesterolaemia

, 2018; 24(31): 3597 - 3598

Michael Doumas, Konstantinos Imprialos, Konstantinos Stavropoulos and Vasilios G. Athyros





Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis

, 2018; 24(26): 3143 - 3151

Alexander N. Orekhov*, Yumiko Oishi , Nikita G. Nikiforov, Andrey V. Zhelankin, Larisa Dubrovsky, Igor A. Sobenin, Alexander Kel, Daria Stelmashenko, Vsevolod J. Makeev, Kathy Foxx, Xueting Jin, Howard S. Kruth and Michael Bukrinsky




Novel Technologies for Dipeptide Drugs Design and their Implantation

, 2018; 24(26): 3020 - 3027

Tatiana A. Gudasheva*, Rita U. Ostrovskaya and Sergey B. Seredenin




Coronary Microcirculation in Ischemic Heart Disease

, 2018; 24(25): 2893 - 2899

Axel R. Pries*, Wolfgang M. Kuebler and Helmut Habazettl




Next-generation Metabolomics in the Development of New Antidepressants: Using Albiflorin as an Example

, 2018; 24(22): 2530 - 2540

Jian Han, Yonghong Xia, Lejun Lin, Zuoguang Zhang, Hui Tian and Kefeng Li*





Defense Mechanisms Against Acid Exposure by Dental Enamel Formation, Saliva and Pancreatic Juice Production

, 2018; 24(18): 2012 - 2022

Robert Racz, Akos Nagy, Zoltan Rakonczay , Erika Katalin Dunavari, Gabor Gerber and Gabor Varga*





Most Cited Articles

Review Article

Rapid-acting antidepressants

, 2018; 24(22): 2556-2563.

Jeffrey M. Witkin*, Daniel E. Knutson, Gabriel J. Rodriguez and Samuel Shi


DOI: 10.2174/1381612824666180730104707


Review Article

Curcumin: A natural pan-HDAC inhibitor in cancer

, 1 January 2018; 24(2): 123-129.

Sara Saffar Soflaei, Amir Abbas Momtazi-Borojeni, Muhammed Majeed, Giuseppe Derosa, Pamela Maffioli and Amirhossein Sahebkar*


DOI: 10.2174/1381612823666171114165051



Review Article

Polyphenols: Potential use in the prevention and treatment of cardiovascular diseases

, 1 January 2018; 24(2): 239-258.

Rosaria Vincenza Giglio, Angelo Maria Patti, Arrigo F.G. Cicero, Giuseppe Lippi, Manfredi Rizzo*, Peter P. Toth and Maciej Banach


DOI: 10.2174/1381612824666180130112652


Review Article

Antibacterial coatings based on chitosan for pharmaceutical and biomedical applications

, 2018; 24(8): 866-885.

Juliana Miguel Vaz, Daniele Pezzoli, Pascale Chevallier, Clayton Souza Campelo, Gabriele Candiani and Diego Mantovani*


DOI: 10.2174/1381612824666180219143900


Research Article

PNitro-Tyr-PseAAC: Predict nitrotyrosine sites in proteins by incorporating five features into Chou’s general PseAAC

, 2018; 24(34): 4034-4043.

Ahmad W. Ghauri, Yaser D. Khan, Nouman Rasool, Sher A. Khan* and Kuo-Chen Chou


DOI: 10.2174/1381612825666181127101039


Review Article

Recent findings in molecular basis of inflammation and anti-inflammatory plants

, 2018; 24(14): 1551-1562.

Sedigheh Kazemi, Hedayatollah Shirzad and Mahmoud Rafieian-Kopaei*


DOI: 10.2174/1381612824666180403122003


Review Article

Placental exosomes during gestation: Liquid biopsies carrying signals for the regulation of human parturition

, 2018; 24(9): 974-982.

Carlos Salomon*, Zarin Nuzhat, Christopher L. Dixon and Ramkumar Menon*


DOI: 10.2174/1381612824666180125164429


Review Article

Antibacterial metal oxide nanoparticles: Challenges in interpreting the literature

, 2018; 24(8): 896-903.

Usha Kadiyala, Nicholas A. Kotov and J. Scott VanEpps*


DOI: 10.2174/1381612824666180219130659


Review Article

Colchicine pharmacokinetics and mechanism of action

, 2018; 24(6): 659-663.

Christos Angelidis*, Zoi Kotsialou, Charalampos Kossyvakis, Agathi-Rosa Vrettou, Achilleas Zacharoulis, Fotios Kolokathis, Vasilios Kekeris and Georgios Giannopoulos


DOI: 10.2174/1381612824666180123110042


Review Article

Signaling pathways in inflammation and anti-inflammatory therapies

, 2018; 24(14): 1449-1484.

Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*


DOI: 10.2174/1381612824666180327165604



Research Article

Virtual screening and statistical analysis in the design of new caffeine analogues molecules with potential epithelial anticancer activity

, 2018; 24(5): 576-594.

Josivan da Silva Costa*, Karina da Silva Lopes Costa, Josiane Viana Cruz, Ryan da Silva Ramos, Luciane Barros Silva, Davi Do Socorro Barros Brasil, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos and Williams Jorge da Cruz Macedo


DOI: 10.2174/1381612823666170711112510


Review Article

Curcumin as an adjunct therapy and microRNA modulator in breast cancer

, 1 January 2018; 24(2): 171-177.

Saeed Norouzi, Muhammed Majeed, Matteo Pirro, Daniele Generali and Amirhossein Sahebkar*


DOI: 10.2174/1381612824666171129203506




Most Accessed Articles

Advances in Binding Free Energies Calculations: QM/MM-Based Free Energy Perturbation Method for Drug Design

, 2013; 19(26): 4674-4686.

R.S. Rathore, M. Sumakanth, M. Siva Reddy, P. Reddanna, Allam Appa Rao, Mark D. Erion and M.R. Reddy


DOI: 10.2174/1381612811319260002


Recent Advances in Cancer Therapy: An Overview

, 2010; 16(1): 3-10.

A. Urruticoechea, R. Alemany, J. Balart, A. Villanueva, F. Vinals and G. Capella


DOI: 10.2174/138161210789941847


JAK Inhibition: The Most Promising Agents in the IBD Pipeline?

, 2019; 25(1): 32-40.

Agnès Fernández-Clotet, Jesús Castro-Poceiro and Julián Panés*


DOI: 10.2174/1381612825666190405141410


Recent Advances in Half-life Extension Strategies for Therapeutic Peptides and Proteins

, 2018; 24(41): 4932-4946.

Huanbo Tan, Wencheng Su, Wenyu Zhang, Pengju Wang, Michael Sattler and Peijian Zou*


DOI: 10.2174/1381612825666190206105232


Reversal of Novel Anticoagulants in Emergent Surgery and Trauma: A Comprehensive Review and Proposed Management Algorithm

, 2018; 24(38): 4540-4553.

Leonidas Palaiodimos*, Jeremy Miles, Damianos G. Kokkinidis, Christos Barkolias, Anil K. Jonnalagadda, Dimitrios Papaconstantinou, Maximos Frountzas, Evangelos P. Misiakos and Dimitrios Schizas


DOI: 10.2174/1381612825666181226150629




The Transport Mechanism of Extracellular Vesicles at the Blood-Brain Barrier

, 2017; 23(40): 6206-6214.

Junichi Matsumoto, Tessandra Stewart, William A. Banks and Jing Zhang*


DOI: 10.2174/1381612823666170913164738


Computer-aided Drug Design and Drug Pharmacokinetic Prediction: A Mini-review

, 2018; 24(26): 3014-3019.

Jamshid Tabeshpour, Amirhossein Sahebkar*, Mohammad Reza Zirak, Majid Zeinali, Mahmoud Hashemzaei, Sajed Rakhshani and Saleh Rakhshani*


DOI: 10.2174/1381612824666180903123423




Editor-in-Chief

William A. Banks
(29546 citations)
Seattle VA Puget Sound Health Care System
Room 810C, Building 1
1660 S. Columbian Way
Seattle, WA 98108
USA

Biography View Full Editorial Board

Journal History

Current Pharmaceutical Design was introduced in 1995 with the assistance of Dr. William A. Banks, who is the current Editor-in-Chief serving since 1995.
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Scopus CiteScore Metrics: 1.15

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