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Current Pharmaceutical Design

Volume 26, 46 Issues, 2020
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

Ranking and Category

  • 148th of 267 in

    Pharmacology & Pharmacy

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Honorary Senior Advisors

Abba Kastin
Pennington Biomed. Res. Ctr., Baton Rouge
Andrew V. Schally
(Nobel Laureate)
New Orleans, LA
John E. Morley
St. Louis University Health Sciences Center
St. Louis, MO

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design


Volume 26


Number 7

Editorial   Open Access

Review Article

Role of Dietary Antioxidants in Neurodegenerative Diseases: Where are We Standing?

, 26(7): 714 - 729

Sena Bakir, Gizem Catalkaya, Fatma D. Ceylan, Haroon Khan*, Burcu Guldiken, Esra Capanoglu and Mohammad A. Kamal

DOI: 10.2174/1381612826666200107143619

Review Article

Role of Prostaglandins in Multiple Sclerosis

, 26(7): 730 - 742

Surendra Gulla, Dakshayani Lomada, Anusha Lade, Reddanna Pallu and Madhava C. Reddy*

DOI: 10.2174/1381612826666200107141328

Review Article

Multiple Risk Factors: A Challenge in the Management of Autism

, 26(7): 743 - 754

Muhammad S. Nadeem, Fahad A. Al-Abbasi, Imran Kazmi, Bibi N. Murtaza, Mazin A. Zamzami, Mohammad A. Kamal, Amina Arif, Muhammad Afzal and Firoz Anwar*

DOI: 10.2174/1381612826666200226101218

Review Article

Novel Therapeutics for the Treatment of Alzheimer’s and Parkinson’s Disease

, 26(7): 755 - 763

Kavita Singh, Dhananjay Yadav, Pallavi S. Chauhan, Meerambika Mishra and Jun-O Jin*

DOI: 10.2174/1381612826666200107161051

Review Article

Review Article

Emerging Potential of Naturally Occurring Autophagy Modulators Against Neurodegeneration

, 26(7): 772 - 779

Md. Ataur Rahman*, Md Rezanur Rahman, Toyfiquz Zaman, Md. Sahab Uddin, Rokibul Islam, Mohamed M. Abdel-Daim and Hyewhon Rhim*

DOI: 10.2174/1381612826666200107142541

Research Article

A traditional Chinese Medicine, YXQN, Reduces Amyloid-induced Cytotoxicity by Inhibiting Aβ42 Aggregation and Fibril Formation

, 26(7): 780 - 789

Lichun Wang, Sitong Liu, Jiaqi Xu, Nobumoto Watanabe, Jun Di*, Wei Wei, Kevin H. Mayo, Jiang Li* and Xiaomeng Li*

DOI: 10.2174/1381612826666200207120602

Articles Ahead of Print

Focus On The Use Of Resveratrol As Adjuvant In Glioblastoma Theraphy

Lamberto Dionigi, Francesco Ragonese, Lorenzo Monarca, Stefano Covino, Antonella de Luca, Rossana Giulietta Iannitti, Federica Bastioli, Anargyros Moulas, Marcello Allegretti and Bernard Fioretti*

DOI: 10.2174/1381612826666200401085634
View Abstract

Current Nanoparticles Approaches in Nose to Brain Drug Delivery and Anticancer Therapy - A Review

Mohammad Azam Ansari, Ill-Min Chung, Govindasamy Rajakumar, Mohammad A. Alzohairy, Mohammad N. Alomary, Muthu Thiruvengadam*, Faheem Hyder Pottoo and Niyaz Ahmad

DOI: 10.2174/1381612826666200116153912
View Abstract View on PubMed

Recent Nano-based Therapeutic Intervention of Bioactive Sesquiterpenes: Prospects in Cancer Therapeutics

Mohammad Azam Ansari*, Khan Farheen Badrealam, Asrar Alam, Saba Tufail, Gulshan Khalique, Mohammad Javed Equbal, Mohammad A. Alzohairy, Ahmad Almatroudi, Mohammad N. Alomary and Faheem Hyder Pottoo

DOI: 10.2174/1381612826666200116151522
View Abstract View on PubMed

Therapeutic Nanoemulsion: Concept to Delivery

Md Abul Barkat, Md. Rizwanullah, Faheem Hyder Pottoo, Sarwar Beg, Farhan J Ahmad, Sohail Akhter* and Harshita

DOI: 10.2174/1381612826666200317140600
View Abstract View on PubMed

Lipid-Based Nanosystem As Intelligent Carriers for Versatile Drug Delivery Applications

Harshita, Md Abul Barkat, Sabya Sachi Das, Faheem Hyder Pottoo, Sarwar Beg and Ziyaur Rahman*

DOI: 10.2174/1381612826666200206094529
View Abstract View on PubMed

Polymer-Lipid Hybrid Nanoparticles: A Next-Generation Nanocarrier for Targeted Treatment of Solid Tumors

Md. Rizwanullah, Meraj Alam, Harshita, Showkat Rasool Mir, Mohd. Moshahid Alam Rizvi and Saima Amin*

DOI: 10.2174/1381612826666200116150426
View Abstract View on PubMed

Nanomedicines in Diagnosis and Treatment of Cancer: An Update

Nafis Haider, Sana Fatima, Murtada Tahar, Jamia Firdous, Rafeeque Ahmad , Faizan Mazhar and Mohammad Ahmed Khan*

DOI: 10.2174/1381612826666200318170716
View Abstract View on PubMed

Abstracts Ahead of Print

Direct Cardiac Reprogramming with Engineered miRNA Scaffolds

Priyadharshni Muniyandi, Toru Maekawa , Tatsuro Hanajiri and Vivekanandan Palaninathan *

DOI: 10.2174/1381612826666200327161112
View Abstract


Hericalizandra Santana, Fernanda Carvalho, Erika Silva , Nayara Santos, Débora Santos , Julio Wisniewski , José Cardoso Júnior , Paula Nunes , Saranavan Shanmugam , Ricardo Luiz de Albuquerque Júnior , Adriano Araújo and Márcio Roberto*

DOI: 10.2174/1381612826666200320130443
View Abstract

Utilizing ICG spectroscopical properties for real-time nanoparticle release quantification in vitro and in vivo in imaging setups

Tuula Peñate-Medina, Eike Kraas, Kunliang Luo, Jana Humbert, Hanwen Zhu, Fabian Mertens, Mirko Gerle, Arndt Rochweder , Christabel Damoah, Olga Will, Yahya Acild, Kalevi Kairemo, Claus C GIIuer, Regine ScherlieB , Susanne Sebens, Oula Peñate-Medina* and Jörg Wiltfang

DOI: 10.2174/1381612826666200318170849
View Abstract

Pathways involved in premature ovarian failure: A systematic review of experimental studies

Michail Pargianas, Styliani Salta, Katerina Apostolopoulou, Leandros Lazaros , Maria Kyrgiou, Andrea Tinelli, Antonio Malvasi, Ioannis Kalogiannidis, Ioannis Georgiou and Ioannis P. Kosmas*

DOI: 10.2174/1381612826666200316160145
View Abstract

Lnc RNAs in metabolic and inflammatory pathways

Yue Shi, Jiayuan Qu, Liyue Gai, Chengfu Yuan and Ding Yuan*

DOI: 10.2174/1381612826666200316143842
View Abstract

Liposomes: Novel Drug Delivery Approach for Targeting Parkinson’s Disease

Bhumika Kumar, Mukesh Pandey, Faheem Hyder Pottoo, Faizana Fayaz, Anjali Sharma and P.K. Sahoo*

DOI: 10.2174/1381612826666200128145124
View Abstract

Published Contents

Editor's Choice

Role of Prostaglandins in Multiple Sclerosis

, 2020; 26(7): 730 - 742

Surendra Gulla, Dakshayani Lomada, Anusha Lade, Reddanna Pallu and Madhava C. Reddy*

DOI: 10.2174/1381612826666200107141328

Aptamers Which Target Proteins: What Proteotronics Suggests to Pharmaceutics

, 2020; 26(3): 363 - 371

Rosella Cataldo, Giorgio De Nunzio*, Jean-Francois Millithaler and Eleonora Alfinito

DOI: 10.2174/1381612826666200114095027

Traditional Risk Factors are Causally Related to Carotid Intima-Media Thickness Progression: Inferences from Observational Cohort Studies and Interventional Trials

, 2020; 26(1): 11 - 24

Beatrice Frigerio, José P. Werba, Mauro Amato, Alessio Ravani, Daniela Sansaro, Daniela Coggi, Lorenzo Vigo, Elena Tremoli and Damiano Baldassarre*

DOI: 10.2174/1381612825666191213120339

Energy-Sensing Pathways in Ischemia: The Counterbalance Between AMPK and mTORC

, 2019; 25(45): 4763 - 4770

Angel Cespedes, Mario Villa, Irene Benito-Cuesta*, Maria J. Perez-Alvarez , Lara Ordoñez and Francisco Wandosell*

DOI: 10.2174/1381612825666191210152156

The effect of Endovascular Aneurysm Repair on Renal Function in Patients Treated for Abdominal Aortic Aneurysm

, 2019; 25(44): 4675 - 4685

Petroula Nana*, George Kouvelos, Alexandros Brotis, Konstantinos Spanos, Athanasios Giannoukas and Miltiadis Matsagkas

DOI: 10.2174/1381612825666191129094923

Neurofilament Proteins as Prognostic Biomarkers in Neurological Disorders

, 2019; 25(43): 4560 - 4569

Yichen Lee, Bo H. Lee, William Yip, Pingchen Chou and Bak-Sau Yip*

DOI: 10.2174/1381612825666191210154535

Open Access Articles

Specificity and Continuity of Schizophrenia and Bipolar Disorder: Relation to Biomarkers

, 2020; 26(2): 191 - 200

Yuji Yamada, Madoka Matsumoto, Kazuki Iijima and Tomiki Sumiyoshi*

RHPN1-AS1 Drives the Progression of Hepatocellular Carcinoma via Regulating miR-596/IGF2BP2 Axis

, 2019; 25(43): 4630 - 4640

Hu Fen, Zheng Hongmin, Wei Wei, Yang Chao, Yao Yang, Liu Bei and Sun Zhihua*

Probucol-induced hERG Channel Reduction can be Rescued by Matrine and Oxymatrine in vitro

, 2019; 25(43): 4606 - 4612

Yuan-Qi Shi, Pan Fan, Guo-Cui Zhang, Yu-Hao Zhang, Ming-Zhu Li, Fang Wang and Bao-Xin Li*

Nanomedicines to Treat Skin Pathologies with Natural Molecules

, 2019; 25(21): 2323 - 2337

Elisabetta Esposito*, Claudio Nastruzzi, Maddalena Sguizzato and Rita Cortesi

The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity

, 2019; 25(19): 2192 - 2198

Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*

Impact of Antioxidant Natural Compounds on the Thyroid Gland and Implication of the Keap1/Nrf2 Signaling Pathway

, 2019; 25(16): 1828 - 1846

Ana Paunkov, Dionysios V. Chartoumpekis, Panos G. Ziros, Niki Chondrogianni, Thomas W. Kensler and Gerasimos P. Sykiotis*

Effects of As2O3 and Resveratrol on the Proliferation and Apoptosis of Colon Cancer Cells and the hERG-mediated Potential Mechanisms

, 2019; 25(12): 1385 - 1391

Caichuan Yan*, Fengmei Li*, Yuhao Zhang, Yang Li, Mingzhu Li, Fang Wang, Guocui Zhang, Yuexin Li, Baoxin Li and Xin Zhao

Emerging Therapeutic Targets in Oncologic Photodynamic Therapy

, 2018; 24(44): 5268 - 5295

Gina Manda*, Mihail E. Hinescu, Ionela V. Neagoe, Luis F.V. Ferreira, Rica Boscencu, Paul Vasos, Selma H. Basaga and Antonio Cuadrado

Small Molecules as PD-1/PD-L1 Pathway Modulators for Cancer Immunotherapy

, 2018; 24(41): 4911 - 4920

Peifu Jiao, Qiaohong Geng*, Peng Jin, Gaoxing Su, Houyun Teng, Jinlong Dong and Bing Yan*

Most Cited Articles

Review Article

Recent advances of in-silico modeling of potent antagonists for the adenosine receptors

, 2019; 25(7): 750-773.

Pabitra Narayan Samanta, Supratik Kar* and Jerzy Leszczynski*

DOI: 10.2174/1381612825666190304123545

Review Article

Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning

, 2019; 25(33): 3519-3535.

Md. Tanvir Kabir, Md. Sahab Uddin*, Mst. Marium Begum, Shanmugam Thangapandiyan, Md. Sohanur Rahman, Lotfi Aleya, Bijo Mathew, Muniruddin Ahmed, George E. Barreto and Ghulam Md. Ashraf

DOI: 10.2174/1381612825666191008103141

Review Article

Expression profile of MicroRNA: An emerging hallmark of cancer

, 2019; 25(6): 642-653.

Uzma Zaheer, Muhammed Faheem, Ishtiaq Qadri, Nargis Begum, Hadi M. Yassine, Asmaa A. Al Thani and Shilu Mathew*

DOI: 10.2174/1386207322666190325122821

Review Article

NMDA receptor antagonists: Repositioning of memantine as a multitargeting agent for Alzheimer's therapy

, 2019; 25(33): 3506-3518.

Md. Tanvir Kabir, Mohammad A. Sufian, Md. Sahab Uddin*, Mst. Marium Begum, Shammi Akhter, Ariful Islam, Bijo Mathew, Md. Siddiqul Islam, Md. Shah Amran and Ghulam Md. Ashraf*

DOI: 10.2174/1381612825666191011102444

Review Article

Therapeutic potential of curcumin in the treatment of glioblastoma multiforme

, 2019; 25(3): 333-342.

Seyed Hossein Shahcheraghi, Mahtab Zangui, Marzieh Lotfi, Majid Ghayour-Mobarhan, Ahmad Ghorbani, Hossein Zarei Jaliani, Hamid Reza Sadeghnia and Amirhossein Sahebkar*

DOI: 10.2174/1381612825666190313123704

Review Article

Synthesis of silver nanoparticles and their biomedical applications a comprehensive review

, 2019; 25(24): 2650-2660.

Rajasree Shanmuganathan, Indira Karuppusamy, Muthupandian Saravanan, Harshiny Muthukumar, Kumar Ponnuchamy, Vijayan Sri Ramkumar and Arivalagan Pugazhendhi*

DOI: 10.2174/1381612825666190708185506

Review Article

Human placental vascular reactivity in health and disease: Implications for the treatment of pre-eclampsia

, 2019; 25(5): 505-527.

Emilie Hitzerd*, Michelle Broekhuizen, Rugina I. Neuman, Katrina M. Mirabito Colafella, Daphne Merkus, Sam Schoenmakers, Sinno H.P. Simons, Irwin K.M. Reiss and A. H. Jan Danser

DOI: 10.2174/1381612825666190405145228

Review Article

Extracellular vesicles as drug delivery systems - Methods of production and potential therapeutic applications

, 2019; 25(2): 132-154.

Magdalena Surman, Anna Drożdż, Ewa Stępień and Małgorzata Przybyło*

DOI: 10.2174/1381612825666190306153318

Review Article

Diabetes and vascular disease: Is it all about glycemia?

, 2019; 25(29): 3112-3127.

Alessandra Vecchié, Fabrizio Montecucco, Federico Carbone, Franco Dallegri and Aldo Bonaventura*

DOI: 10.2174/1381612825666190830181944

Review Article

Obesity, metabolic syndrome and the risk of microvascular complications in patients with diabetes mellitus

, 2019; 25(18): 2051-2059.

Niki Katsiki*, Panagiotis Anagnostis, Kalliopi Kotsa, Dimitrios G. Goulis and Dimitri P. Mikhailidis

DOI: 10.2174/1381612825666190708192134

Review Article

Alginate nanoparticles for drug delivery and targeting

, 2019; 25(11): 1312-1334.

Patricia Severino, Classius F. da Silva, Luciana N. Andrade, Daniele de Lima Oliveira, Joana Campos and Eliana B. Souto*

DOI: 10.2174/1381612825666190425163424

Most Accessed Articles

Signaling Pathways in Inflammation and Anti-inflammatory Therapies

, 2018; 24(14): 1449-1484.

Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*

DOI: 10.2174/1381612824666180327165604

Nanomedicines to Treat Skin Pathologies with Natural Molecules

, 2019; 25(21): 2323-2337.

Elisabetta Esposito*, Claudio Nastruzzi, Maddalena Sguizzato and Rita Cortesi

DOI: 10.2174/1381612825666190709210703

Clinical Phenotypes of Severe Cutaneous Drug Hypersensitivity Reactions

, 2019; 25(36): 3840-3854.

Hakan Guvenir, Tugba Arikoglu, Emine Vezir and Emine Dibek Misirlioglu*

DOI: 10.2174/1381612825666191107162921

The Transport Mechanism of Extracellular Vesicles at the Blood-Brain Barrier

, 2017; 23(40): 6206-6214.

Junichi Matsumoto, Tessandra Stewart, William A. Banks and Jing Zhang*

DOI: 10.2174/1381612823666170913164738


William A. Banks
(45093 citations)
Seattle VA Puget Sound Health Care System
Room 810C, Building 1
1660 S. Columbian Way
Seattle, WA 98108

Biography View Full Editorial Board

Journal History

Current Pharmaceutical Design was introduced in 1995 with the assistance of Dr. William A. Banks, who is the current Editor-in-Chief serving since 1995.
Scopus CiteScore Metrics: 2.32



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