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Current Pharmaceutical Design

Volume 26, 46 Issues, 2020
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access
Order Your Article Before PrintSubscribe to this Journal

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

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Volume 26

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Number 23



Editorial   Open Access

Current Antithrombotic Therapy: Beyond Coronary Artery Disease

, 26(23): 2683 - 2685

Vasiliki-Chara Mystakidi, Evangelos Oikonomou and Dimitris Tousoulis


DOI: 10.2174/138161282623200625103419


Systematic Review Article



Review Article

Anticoagulation in Deep Venous Thrombosis: Current Trends in the Era of Non- Vitamin K Antagonists Oral Anticoagulants

, 26(23): 2692 - 2702

Panteleimon E. Papakonstantinou, Costas Tsioufis*, Dimitris Konstantinidis, Panagiotis Iliakis, Ioannis Leontsinis and Dimitrios Tousoulis


DOI: 10.2174/1381612826666200420150517


Review Article

Antithrombotic Treatment after Atrial Fibrillation Ablation

, 26(23): 2703 - 2714

Christos-Konstantinos Antoniou*, Panagiota Manolakou, Petros Arsenos, Polychronis Dilaveris, Konstantinos Gatzoulis and Dimitrios Tousoulis


DOI: 10.2174/1381612826666200407154329


Review Article

Antithrombotic Therapy in Patients with Recent Stroke and Atrial Fibrillation

, 26(23): 2715 - 2724

Bunny Saberwal, Adam Ioannou, Wei Y. Lim, Anne-Marie Beirne, Anthony W. Chow, Dimitris Tousoulis, Syed Ahsan and Nikolaos Papageorgiou*


DOI: 10.2174/1381612826666200407150307


Review Article

Antithrombotic Therapy in Carotid Artery Disease

, 26(23): 2725 - 2734

Paraskevi Papanikolaou, Alexios S. Antonopoulos, Irene Mastorakou, Andreas Angelopoulos, Efthalia Kostoula, Xara-Vasiliki Mystakidi, Spyros Simantiris, Nikolaos Galiatsatos, Evangelos Oikonomou and Dimitris Tousoulis*


DOI: 10.2174/1381612826666200518111359


Review Article

The Role of Antithrombotic Therapy in Heart Failure

, 26(23): 2735 - 2761

Christina Chrysohoou, Nikolaos Magkas*, Christos-Konstantinos Antoniou, Panagiota Manolakou, Aggeliki Laina and Dimitrios Tousoulis


DOI: 10.2174/1381612826666200531151823


Review Article

Antithrombotic Treatment in Cardiomyopathies

, 26(23): 2762 - 2768

Georgia Vogiatzi*, Antonios Pantazis and Dimitris Tousoulis


DOI: 10.2174/1381612826666200429230726


Current Pharmaceutical Design, Volume 26 (2020) - Number 27


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 26 (2020) - Number 26


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 26 (2020) - Number 25


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 26 (2020) - Number 24


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Renin-angiotensin system inhibitors and development of hepatocellular carcinoma: A systematic review and meta-analysis


Fereshteh Asgharzadeh, Reza Jafarzadeh-Esfehani, Seyed Mahdi Hassanian, Gordon A Ferns, Amir Avan and Majid Khazaei*


DOI: 10.2174/1381612826666200713165018
View Abstract


Current Status of the COVID-19 Outbreak and Emerging Management through Pharmaceutical Therapeutic Strategy


Tapan Behl, Md. Habibur Rahman, Rokeya Akter, Md. Arifur Rahman Chowdhury, Manirujjaman Mohammed, Israt Jahan Bulbul, Shimaa E. Elshenawyand and Mohammad Amjad Kamal*


DOI: 10.2174/1381612826666200713174140
View Abstract


The Anticancer Potential of Apigenin via Immunoregulation


Lu Xu, Mohamed Y. Zaky, Waleed Yousuf, Anwar Ullah, Gehad R. Abdelbaset, Yingqiu Zhang, Osama M. Ahmed, Shuyan Liu and Han Liu*


DOI: 10.2174/1381612826666200713171137
View Abstract




Pathophysiology of ischemic stroke: role of oxidative stress


Sofía Orellana-Urzúa, Ignacio Rojas, Lucas Líbano and Ramón Rodrigo*


DOI: 10.2174/1381612826666200708133912
View Abstract



Repurposing Drugs for the Management of Patients with Confirmed Coronavirus Disease 2019 (COVID-19)


Evellyn Claudia Wietzikoski Lovato, Lorena Neris Barboza, Samantha Wietzikoski, Amanda Nascimento Vasques de Souza, Pablo Alvarez Auth, Arquimedes Gasparotto Junior and Francislaine Aparecida dos Reis Lívero*


DOI: 10.2174/1381612826666200707121636
View Abstract


The role of Chloroquine and Hydroxychloroquine in Immune Regulation and Diseases


Gricelis P. Martinez, Mercedes E. Zabaleta, Camilo Di Giulio, Jaime E. Charris and Michael R. Mijares*


DOI: 10.2174/1381612826666200707132920
View Abstract



Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Antithrombotic Therapy in Patients with Recent Stroke and Atrial Fibrillation

, 2020; 26(23): 2715 - 2724

Bunny Saberwal, Adam Ioannou, Wei Y. Lim, Anne-Marie Beirne, Anthony W. Chow, Dimitris Tousoulis, Syed Ahsan and Nikolaos Papageorgiou*


DOI: 10.2174/1381612826666200407150307



The Influence of Vitamin D on Neurodegeneration and Neurological Disorders: A Rationale for its Physio-pathological Actions

, 2020; 26(21): 2475 - 2491

Maria Morello*, Massimo Pieri, Rossella Zenobi, Alessandra Talamo, Delphine Stephan, Verena Landel, François Féron and Pascal Millet


DOI: 10.2174/1381612826666200316145725




Nose to Brain Delivery of Nanocarriers Towards Attenuation of Demented Condition

, 2020; 26(19): 2233 - 2246

Bapi Gorain*, Davinaa C. Rajeswary, Manisha Pandey, Prashant Kesharwani, Santosh A. Kumbhar and Hira Choudhury*


DOI: 10.2174/1381612826666200313125613



Focus on the Use of Resveratrol as an Adjuvant in Glioblastoma Therapy

, 2020; 26(18): 2102 - 2108

Lamberto Dionigi, Francesco Ragonese, Lorenzo Monarca, Stefano Covino, Antonella de Luca, Rossana G. Iannitti, Federica Bastioli, Anargyros N. Moulas, Marcello Allegretti* and Bernard Fioretti*


DOI: 10.2174/1381612826666200401085634



Progress of Mesenchymal Stem Cell-Derived Exosomes in Tissue Repair

, 2020; 26(17): 2022 - 2037

Guifang Zhao, Yiwen Ge, Chenyingnan Zhang, Leyi Zhang, Junjie Xu*, Ling Qi* and Wenliang Li


DOI: 10.2174/1381612826666200420144805



Advances in Nanoparticles as Anticancer Drug Delivery Vector: Need of this Century

, 2020; 26(15): 1637 - 1649

Imran Ali*, Sofi D. Mukhtar, Heyam S. Ali, Marcus T. Scotti and Luciana Scotti*


DOI: 10.2174/1381612826666200203124330



Setting New Routes for Antifungal Drug Discovery Against Pathogenic Fungi

, 2020; 26(14): 1509 - 1520

Kleber S. Freitas e Silva*, Lívia C. Silva, Relber A. Gonçales, Bruno J. Neves, Célia M.A. Soares and Maristela Pereira*


DOI: 10.2174/1381612826666200317125956



Circulating MicroRNAs and Blood-Brain-Barrier Function in Breast Cancer Metastasis

, 2020; 26(13): 1417 - 1427

Carolin J. Curtaz, Constanze Schmitt, Kinga G. Blecharz-Lang, Norbert Roewer, Achim Wöckel and Malgorzata Burek*


DOI: 10.2174/1381612826666200316151720




Open Access Articles

Vaccinium myrtillus L. Fruits as a Novel Source of Phenolic Compounds with Health Benefits and Industrial Applications - A Review

, 2020; 26(16): 1917 - 1928

Tânia C. S. P. Pires , Cristina Caleja , Celestino Santos-Buelga , Lillian Barros* and Isabel C.F.R. Ferreira*





Role of microRNA and Long Non-Coding RNA in Hepatocellular Carcinoma

, 2020; 26(4): 415 - 428

Meenakshi Gupta, Kumari Chandan and Maryam Sarwat*




Burden and Prevention of HPV. Knowledge, Practices and Attitude Assessment Among Pre-Adolescents and their Parents in Italy

, 2020; 26(3): 326 - 342

Giancarlo Icardi, Claudio Costantino, Marcello Guido, Antonella Zizza, Vincenzo Restivo, Daniela Amicizia, Federico Tassinari, Maria Francesca Piazza, Chiara Paganino, Alessandra Casuccio, Francesco Vitale, Filippo Ansaldi and Cecilia Trucchi*




Specificity and Continuity of Schizophrenia and Bipolar Disorder: Relation to Biomarkers

, 2020; 26(2): 191 - 200

Yuji Yamada, Madoka Matsumoto, Kazuki Iijima and Tomiki Sumiyoshi*




RHPN1-AS1 Drives the Progression of Hepatocellular Carcinoma via Regulating miR-596/IGF2BP2 Axis

, 2019; 25(43): 4630 - 4640

Hu Fen, Zheng Hongmin, Wei Wei, Yang Chao, Yao Yang, Liu Bei and Sun Zhihua*




Probucol-induced hERG Channel Reduction can be Rescued by Matrine and Oxymatrine in vitro

, 2019; 25(43): 4606 - 4612

Yuan-Qi Shi, Pan Fan, Guo-Cui Zhang, Yu-Hao Zhang, Ming-Zhu Li, Fang Wang and Bao-Xin Li*





Nanomedicines to Treat Skin Pathologies with Natural Molecules

, 2019; 25(21): 2323 - 2337

Elisabetta Esposito*, Claudio Nastruzzi, Maddalena Sguizzato and Rita Cortesi




The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity

, 2019; 25(19): 2192 - 2198

Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*




Impact of Antioxidant Natural Compounds on the Thyroid Gland and Implication of the Keap1/Nrf2 Signaling Pathway

, 2019; 25(16): 1828 - 1846

Ana Paunkov, Dionysios V. Chartoumpekis, Panos G. Ziros, Niki Chondrogianni, Thomas W. Kensler and Gerasimos P. Sykiotis*






Effects of As2O3 and Resveratrol on the Proliferation and Apoptosis of Colon Cancer Cells and the hERG-mediated Potential Mechanisms

, 2019; 25(12): 1385 - 1391

Caichuan Yan*, Fengmei Li*, Yuhao Zhang, Yang Li, Mingzhu Li, Fang Wang, Guocui Zhang, Yuexin Li, Baoxin Li and Xin Zhao






Most Cited Articles

General Review Article

Long non-coding RNAs as epigenetic regulators in cancer

, 2019; 25(33): 3563-3577.

Asma Vafadar, Zahra Shabaninejad, Ahmad Movahedpour, Soheila Mohammadi, Sima Fathullahzadeh, Hamid R. Mirzaei, Afshin Namdar, Amir Savardashtaki* and Hamed Mirzaei*


DOI: 10.2174/1381612825666190830161528


Review Article

Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning

, 2019; 25(33): 3519-3535.

Md. Tanvir Kabir, Md. Sahab Uddin*, Mst. Marium Begum, Shanmugam Thangapandiyan, Md. Sohanur Rahman, Lotfi Aleya, Bijo Mathew, Muniruddin Ahmed, George E. Barreto and Ghulam Md. Ashraf


DOI: 10.2174/1381612825666191008103141


Review Article

NMDA receptor antagonists: Repositioning of memantine as a multitargeting agent for Alzheimer's therapy

, 2019; 25(33): 3506-3518.

Md. Tanvir Kabir, Mohammad A. Sufian, Md. Sahab Uddin*, Mst. Marium Begum, Shammi Akhter, Ariful Islam, Bijo Mathew, Md. Siddiqul Islam, Md. Shah Amran and Ghulam Md. Ashraf*


DOI: 10.2174/1381612825666191011102444


Review Article

Synthesis of silver nanoparticles and their biomedical applications a comprehensive review

, 2019; 25(24): 2650-2660.

Rajasree Shanmuganathan, Indira Karuppusamy, Muthupandian Saravanan, Harshiny Muthukumar, Kumar Ponnuchamy, Vijayan Sri Ramkumar and Arivalagan Pugazhendhi*


DOI: 10.2174/1381612825666190708185506





Review Article

Expression profile of MicroRNA: An emerging hallmark of cancer

, 2019; 25(6): 642-653.

Uzma Zaheer, Muhammed Faheem, Ishtiaq Qadri, Nargis Begum, Hadi M. Yassine, Asmaa A. Al Thani and Shilu Mathew*


DOI: 10.2174/1386207322666190325122821


Review Article

Emerging potential of naturally occurring autophagy modulators against neurodegeneration

, 2020; 26(7): 772-779.

Md. Ataur Rahman*, Md Rezanur Rahman, Toyfiquz Zaman, Md. Sahab Uddin, Rokibul Islam, Mohamed M. Abdel-Daim and Hyewhon Rhim*


DOI: 10.2174/1381612826666200107142541



Review Article

Recent advances of in-silico modeling of potent antagonists for the adenosine receptors

, 2019; 25(7): 750-773.

Pabitra Narayan Samanta, Supratik Kar* and Jerzy Leszczynski*


DOI: 10.2174/1381612825666190304123545



Review Article

Alginate nanoparticles for drug delivery and targeting

, 2019; 25(11): 1312-1334.

Patricia Severino, Classius F. da Silva, Luciana N. Andrade, Daniele de Lima Oliveira, Joana Campos and Eliana B. Souto*


DOI: 10.2174/1381612825666190425163424


Review Article

Novel pathways in the treatment of major depression: Focus on the glutamatergic system

, 2019; 25(4): 381-387.

Carmine Tomasetti , Chiara Montemitro, Annastasia L. C. Fiengo , Cristina Santone , Laura Orsolini , Alessandro Valchera, Alessandro Carano, Maurizio Pompili , Gianluca Serafini , Giampaolo Perna, Federica Vellante, Giovanni Martinotti, Massimo Di Giannantonio , Yong-Ku Kim, Marco D. Nicola , Antonello Bellomo, Antonio Ventriglio , Michele Fornaro and Domenico D. Berardis*


DOI: 10.2174/1381612825666190312102444


Review Article

Human placental vascular reactivity in health and disease: Implications for the treatment of pre-eclampsia

, 2019; 25(5): 505-527.

Emilie Hitzerd*, Michelle Broekhuizen, Rugina I. Neuman, Katrina M. Mirabito Colafella, Daphne Merkus, Sam Schoenmakers, Sinno H.P. Simons, Irwin K.M. Reiss and A. H. Jan Danser


DOI: 10.2174/1381612825666190405145228



Most Accessed Articles

Signaling Pathways in Inflammation and Anti-inflammatory Therapies

, 2018; 24(14): 1449-1484.

Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*


DOI: 10.2174/1381612824666180327165604




A Review on Cancer Therapy Based on the Photothermal Effect of Gold Nanorod

, 2019; 25(46): 4836-4847.

Weizhen Xu, Qinlu Lin, Yueqin Yin, Dong Xu*, Xiaohui Huang, Bucheng Xu and Guangwei Wang*


DOI: 10.2174/1381612825666191216150052



Neurofilament Proteins as Prognostic Biomarkers in Neurological Disorders

, 2019; 25(43): 4560-4569.

Yichen Lee, Bo H. Lee, William Yip, Pingchen Chou and Bak-Sau Yip*


DOI: 10.2174/1381612825666191210154535


Clinical Phenotypes of Severe Cutaneous Drug Hypersensitivity Reactions

, 2019; 25(36): 3840-3854.

Hakan Guvenir, Tugba Arikoglu, Emine Vezir and Emine Dibek Misirlioglu*


DOI: 10.2174/1381612825666191107162921


Nanomedicines to Treat Skin Pathologies with Natural Molecules

, 2019; 25(21): 2323-2337.

Elisabetta Esposito*, Claudio Nastruzzi, Maddalena Sguizzato and Rita Cortesi


DOI: 10.2174/1381612825666190709210703


Therapeutic Potential of Agonists and Antagonists of A1, A2a, A2b and A3 Adenosine Receptors

, 2019; 25(26): 2892-2905.

Sumit Jamwal, Ashish Mittal, Puneet Kumar*, Dana M. Alhayani and Amal Al-Aboudi


DOI: 10.2174/1381612825666190716112319




Editor-in-Chief

William A. Banks
(45093 citations)
Seattle VA Puget Sound Health Care System
Room 810C, Building 1
1660 S. Columbian Way
Seattle, WA 98108
(USA)
Biography View Full Editorial Board

Nobel Laureate on Editorial Board

Andrew V. Schally
(USA)

Journal History

Current Pharmaceutical Design was introduced in 1995 with the assistance of Dr. William A. Banks, who is the current Editor-in-Chief serving since 1995.
Scopus CiteScore Metrics: 2.32

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