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Current Pharmaceutical Design

Volume 26, 46 Issues, 2020
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

Ranking and Category

  • 148th of 267 in

    Pharmacology & Pharmacy

Order Your Article Before Print

Honorary Senior Advisors

Abba Kastin
Pennington Biomed. Res. Ctr., Baton Rouge
LA
USA
Biography
Andrew V. Schally
(Nobel Laureate)
VAMC
New Orleans, LA
USA
Biography
John E. Morley
St. Louis University Health Sciences Center
St. Louis, MO
USA
Biography

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

,

Volume 26

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Number 7



Editorial   Open Access



Review Article

Role of Dietary Antioxidants in Neurodegenerative Diseases: Where are We Standing?

, 26(7): 714 - 729

Sena Bakir, Gizem Catalkaya, Fatma D. Ceylan, Haroon Khan*, Burcu Guldiken, Esra Capanoglu and Mohammad A. Kamal


DOI: 10.2174/1381612826666200107143619


Review Article

Role of Prostaglandins in Multiple Sclerosis

, 26(7): 730 - 742

Surendra Gulla, Dakshayani Lomada, Anusha Lade, Reddanna Pallu and Madhava C. Reddy*


DOI: 10.2174/1381612826666200107141328


Review Article

Multiple Risk Factors: A Challenge in the Management of Autism

, 26(7): 743 - 754

Muhammad S. Nadeem, Fahad A. Al-Abbasi, Imran Kazmi, Bibi N. Murtaza, Mazin A. Zamzami, Mohammad A. Kamal, Amina Arif, Muhammad Afzal and Firoz Anwar*


DOI: 10.2174/1381612826666200226101218


Review Article

Novel Therapeutics for the Treatment of Alzheimer’s and Parkinson’s Disease

, 26(7): 755 - 763

Kavita Singh, Dhananjay Yadav, Pallavi S. Chauhan, Meerambika Mishra and Jun-O Jin*


DOI: 10.2174/1381612826666200107161051


Review Article



Review Article

Emerging Potential of Naturally Occurring Autophagy Modulators Against Neurodegeneration

, 26(7): 772 - 779

Md. Ataur Rahman*, Md Rezanur Rahman, Toyfiquz Zaman, Md. Sahab Uddin, Rokibul Islam, Mohamed M. Abdel-Daim and Hyewhon Rhim*


DOI: 10.2174/1381612826666200107142541


Research Article

A traditional Chinese Medicine, YXQN, Reduces Amyloid-induced Cytotoxicity by Inhibiting Aβ42 Aggregation and Fibril Formation

, 26(7): 780 - 789

Lichun Wang, Sitong Liu, Jiaqi Xu, Nobumoto Watanabe, Jun Di*, Wei Wei, Kevin H. Mayo, Jiang Li* and Xiaomeng Li*


DOI: 10.2174/1381612826666200207120602


Articles Ahead of Print

Neuropharmacological Characterization of Dioclea altissima Seed Lectin (DAL) in Mice: Evidence of Anxiolytic-like Effect Mediated by Serotonergic, GABAergic Receptors and NO Pathway


João Ronielly Campêlo Araújo, Adriana Rolim Campos, Marina de Barros Mamede Vidal Damasceno, Sacha Aubrey Alves Rodrigues Santos, Maria Kueirislene Amâncio Ferreira, Renato de Azevedo Moreira and Ana Cristina de Oliveira Monteiro-Moreira*


DOI: 10.2174/1381612826666200331093207
View Abstract View on PubMed




Non-pharmacological Strategies Against Systemic Inflammation: Molecular Basis and Clinical Evidence.


Rita Del Pinto, Davide Pietropaoli, Annalisa Monaco, Giovambattista Desideri, Claudio Ferri and Davide Grassi*


DOI: 10.2174/1381612826666200403122600
View Abstract



Synthesis of eugenol derivatives and evaluation of their antifungal activity against Fusarium solani f. sp. piperis.


Sarah Canal Maximino, Jessyca Aparecida Paes Dutra, Ricardo Pereira Rodrigues, Rita de Cássia Ribeiro Gonçalves, Pedro Alves Bezerra de Morais, José Aires Ventura, Ricardo Pinto Schuenck, Valdemar Lacerda Júnior, Rodrigo Rezende Kitagawa and Warley de Souza Borges*


DOI: 10.2174/1381612826666200403120448
View Abstract






Abstracts Ahead of Print

Direct Cardiac Reprogramming with Engineered miRNA Scaffolds


Priyadharshni Muniyandi, Toru Maekawa , Tatsuro Hanajiri and Vivekanandan Palaninathan *


DOI: 10.2174/1381612826666200327161112
View Abstract


ANTI-INFLAMMATORY ACTIVITY OF LIMONENE IN PREVENTION AND CONTROL OF INJURIES IN THE RESPIRATORY SYSTEM: A SYSTEMATIC REVIEW


Hericalizandra Santana, Fernanda Carvalho, Erika Silva , Nayara Santos, Débora Santos , Julio Wisniewski , José Cardoso Júnior , Paula Nunes , Saranavan Shanmugam , Ricardo Luiz de Albuquerque Júnior , Adriano Araújo and Márcio Roberto*


DOI: 10.2174/1381612826666200320130443
View Abstract


Utilizing ICG spectroscopical properties for real-time nanoparticle release quantification in vitro and in vivo in imaging setups


Tuula Peñate-Medina, Eike Kraas, Kunliang Luo, Jana Humbert, Hanwen Zhu, Fabian Mertens, Mirko Gerle, Arndt Rochweder , Christabel Damoah, Olga Will, Yahya Acild, Kalevi Kairemo, Claus C GIIuer, Regine ScherlieB , Susanne Sebens, Oula Peñate-Medina* and Jörg Wiltfang


DOI: 10.2174/1381612826666200318170849
View Abstract



Pathways involved in premature ovarian failure: A systematic review of experimental studies


Michail Pargianas, Styliani Salta, Katerina Apostolopoulou, Leandros Lazaros , Maria Kyrgiou, Andrea Tinelli, Antonio Malvasi, Ioannis Kalogiannidis, Ioannis Georgiou and Ioannis P. Kosmas*


DOI: 10.2174/1381612826666200316160145
View Abstract


Lnc RNAs in metabolic and inflammatory pathways


Yue Shi, Jiayuan Qu, Liyue Gai, Chengfu Yuan and Ding Yuan*


DOI: 10.2174/1381612826666200316143842
View Abstract




Liposomes: Novel Drug Delivery Approach for Targeting Parkinson’s Disease


Bhumika Kumar, Mukesh Pandey, Faheem Hyder Pottoo, Faizana Fayaz, Anjali Sharma and P.K. Sahoo*


DOI: 10.2174/1381612826666200128145124
View Abstract


Published Contents

Editor's Choice

Role of Prostaglandins in Multiple Sclerosis

, 2020; 26(7): 730 - 742

Surendra Gulla, Dakshayani Lomada, Anusha Lade, Reddanna Pallu and Madhava C. Reddy*


DOI: 10.2174/1381612826666200107141328





Aptamers Which Target Proteins: What Proteotronics Suggests to Pharmaceutics

, 2020; 26(3): 363 - 371

Rosella Cataldo, Giorgio De Nunzio*, Jean-Francois Millithaler and Eleonora Alfinito


DOI: 10.2174/1381612826666200114095027




Traditional Risk Factors are Causally Related to Carotid Intima-Media Thickness Progression: Inferences from Observational Cohort Studies and Interventional Trials

, 2020; 26(1): 11 - 24

Beatrice Frigerio, José P. Werba, Mauro Amato, Alessio Ravani, Daniela Sansaro, Daniela Coggi, Lorenzo Vigo, Elena Tremoli and Damiano Baldassarre*


DOI: 10.2174/1381612825666191213120339




Energy-Sensing Pathways in Ischemia: The Counterbalance Between AMPK and mTORC

, 2019; 25(45): 4763 - 4770

Angel Cespedes, Mario Villa, Irene Benito-Cuesta*, Maria J. Perez-Alvarez , Lara Ordoñez and Francisco Wandosell*


DOI: 10.2174/1381612825666191210152156



The effect of Endovascular Aneurysm Repair on Renal Function in Patients Treated for Abdominal Aortic Aneurysm

, 2019; 25(44): 4675 - 4685

Petroula Nana*, George Kouvelos, Alexandros Brotis, Konstantinos Spanos, Athanasios Giannoukas and Miltiadis Matsagkas


DOI: 10.2174/1381612825666191129094923



Neurofilament Proteins as Prognostic Biomarkers in Neurological Disorders

, 2019; 25(43): 4560 - 4569

Yichen Lee, Bo H. Lee, William Yip, Pingchen Chou and Bak-Sau Yip*


DOI: 10.2174/1381612825666191210154535



Open Access Articles

Specificity and Continuity of Schizophrenia and Bipolar Disorder: Relation to Biomarkers

, 2020; 26(2): 191 - 200

Yuji Yamada, Madoka Matsumoto, Kazuki Iijima and Tomiki Sumiyoshi*




RHPN1-AS1 Drives the Progression of Hepatocellular Carcinoma via Regulating miR-596/IGF2BP2 Axis

, 2019; 25(43): 4630 - 4640

Hu Fen, Zheng Hongmin, Wei Wei, Yang Chao, Yao Yang, Liu Bei and Sun Zhihua*




Probucol-induced hERG Channel Reduction can be Rescued by Matrine and Oxymatrine in vitro

, 2019; 25(43): 4606 - 4612

Yuan-Qi Shi, Pan Fan, Guo-Cui Zhang, Yu-Hao Zhang, Ming-Zhu Li, Fang Wang and Bao-Xin Li*





Nanomedicines to Treat Skin Pathologies with Natural Molecules

, 2019; 25(21): 2323 - 2337

Elisabetta Esposito*, Claudio Nastruzzi, Maddalena Sguizzato and Rita Cortesi




The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity

, 2019; 25(19): 2192 - 2198

Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*




Impact of Antioxidant Natural Compounds on the Thyroid Gland and Implication of the Keap1/Nrf2 Signaling Pathway

, 2019; 25(16): 1828 - 1846

Ana Paunkov, Dionysios V. Chartoumpekis, Panos G. Ziros, Niki Chondrogianni, Thomas W. Kensler and Gerasimos P. Sykiotis*






Effects of As2O3 and Resveratrol on the Proliferation and Apoptosis of Colon Cancer Cells and the hERG-mediated Potential Mechanisms

, 2019; 25(12): 1385 - 1391

Caichuan Yan*, Fengmei Li*, Yuhao Zhang, Yang Li, Mingzhu Li, Fang Wang, Guocui Zhang, Yuexin Li, Baoxin Li and Xin Zhao





Emerging Therapeutic Targets in Oncologic Photodynamic Therapy

, 2018; 24(44): 5268 - 5295

Gina Manda*, Mihail E. Hinescu, Ionela V. Neagoe, Luis F.V. Ferreira, Rica Boscencu, Paul Vasos, Selma H. Basaga and Antonio Cuadrado






Small Molecules as PD-1/PD-L1 Pathway Modulators for Cancer Immunotherapy

, 2018; 24(41): 4911 - 4920

Peifu Jiao, Qiaohong Geng*, Peng Jin, Gaoxing Su, Houyun Teng, Jinlong Dong and Bing Yan*





Most Cited Articles




Review Article

Recent advances of in-silico modeling of potent antagonists for the adenosine receptors

, 2019; 25(7): 750-773.

Pabitra Narayan Samanta, Supratik Kar* and Jerzy Leszczynski*


DOI: 10.2174/1381612825666190304123545


Review Article

Synthesis of silver nanoparticles and their biomedical applications a comprehensive review

, 2019; 25(24): 2650-2660.

Rajasree Shanmuganathan, Indira Karuppusamy, Muthupandian Saravanan, Harshiny Muthukumar, Kumar Ponnuchamy, Vijayan Sri Ramkumar and Arivalagan Pugazhendhi*


DOI: 10.2174/1381612825666190708185506


Review Article

Expression profile of MicroRNA: An emerging hallmark of cancer

, 2019; 25(6): 642-653.

Uzma Zaheer, Muhammed Faheem, Ishtiaq Qadri, Nargis Begum, Hadi M. Yassine, Asmaa A. Al Thani and Shilu Mathew*


DOI: 10.2174/1386207322666190325122821


Review Article

Therapeutic potential of curcumin in the treatment of glioblastoma multiforme

, 2019; 25(3): 333-342.

Seyed Hossein Shahcheraghi, Mahtab Zangui, Marzieh Lotfi, Majid Ghayour-Mobarhan, Ahmad Ghorbani, Hossein Zarei Jaliani, Hamid Reza Sadeghnia and Amirhossein Sahebkar*


DOI: 10.2174/1381612825666190313123704


Review Article

Human placental vascular reactivity in health and disease: Implications for the treatment of pre-eclampsia

, 2019; 25(5): 505-527.

Emilie Hitzerd*, Michelle Broekhuizen, Rugina I. Neuman, Katrina M. Mirabito Colafella, Daphne Merkus, Sam Schoenmakers, Sinno H.P. Simons, Irwin K.M. Reiss and A. H. Jan Danser


DOI: 10.2174/1381612825666190405145228


Review Article

Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning

, 2019; 25(33): 3519-3535.

Md. Tanvir Kabir, Md. Sahab Uddin*, Mst. Marium Begum, Shanmugam Thangapandiyan, Md. Sohanur Rahman, Lotfi Aleya, Bijo Mathew, Muniruddin Ahmed, George E. Barreto and Ghulam Md. Ashraf


DOI: 10.2174/1381612825666191008103141


Review Article

Women’s beliefs about medicines and adherence to pharmacotherapy in pregnancy: Opportunities for community pharmacists

, 2019; 25(5): 469-482.

Michael Ceulemans*, Angela Lupattelli , Hedvig Nordeng , Marina Odalovic, Michael Twigg and Veerle Foulon


DOI: 10.2174/1381612825666190321110420


General Review Article

Ethnobotany, phytochemistry and traditional uses of curcuma spp. and pharmacological profile of two important species (C. longa and C. zedoaria): A Review

, 2019; 25(8): 871-935.

Zahra Ayati, Mahin Ramezani , Mohammad Sadegh Amiri, Ali Tafazoli Moghadam, Hoda Rahimi, Aref Abdollahzade, Amirhossein Sahebkar * and Seyed Ahmad Emami *


DOI: 10.2174/1381612825666190402163940


Review Article

Extracellular vesicles as drug delivery systems - Methods of production and potential therapeutic applications

, 2019; 25(2): 132-154.

Magdalena Surman, Anna Drożdż, Ewa Stępień and Małgorzata Przybyło*


DOI: 10.2174/1381612825666190306153318


General Review Article

Long non-coding RNAs as epigenetic regulators in cancer

, 2019; 25(33): 3563-3577.

Asma Vafadar, Zahra Shabaninejad, Ahmad Movahedpour, Soheila Mohammadi, Sima Fathullahzadeh, Hamid R. Mirzaei, Afshin Namdar, Amir Savardashtaki* and Hamed Mirzaei*


DOI: 10.2174/1381612825666190830161528


Review Article

NMDA receptor antagonists: Repositioning of memantine as a multitargeting agent for Alzheimer's therapy

, 2019; 25(33): 3506-3518.

Md. Tanvir Kabir, Mohammad A. Sufian, Md. Sahab Uddin*, Mst. Marium Begum, Shammi Akhter, Ariful Islam, Bijo Mathew, Md. Siddiqul Islam, Md. Shah Amran and Ghulam Md. Ashraf*


DOI: 10.2174/1381612825666191011102444




Most Accessed Articles

Signaling Pathways in Inflammation and Anti-inflammatory Therapies

, 2018; 24(14): 1449-1484.

Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*


DOI: 10.2174/1381612824666180327165604




Nanomedicines to Treat Skin Pathologies with Natural Molecules

, 2019; 25(21): 2323-2337.

Elisabetta Esposito*, Claudio Nastruzzi, Maddalena Sguizzato and Rita Cortesi


DOI: 10.2174/1381612825666190709210703




The Transport Mechanism of Extracellular Vesicles at the Blood-Brain Barrier

, 2017; 23(40): 6206-6214.

Junichi Matsumoto, Tessandra Stewart, William A. Banks and Jing Zhang*


DOI: 10.2174/1381612823666170913164738


Clinical Phenotypes of Severe Cutaneous Drug Hypersensitivity Reactions

, 2019; 25(36): 3840-3854.

Hakan Guvenir, Tugba Arikoglu, Emine Vezir and Emine Dibek Misirlioglu*


DOI: 10.2174/1381612825666191107162921






Editor-in-Chief

William A. Banks
(45093 citations)
Seattle VA Puget Sound Health Care System
Room 810C, Building 1
1660 S. Columbian Way
Seattle, WA 98108
USA

Biography View Full Editorial Board

Journal History

Current Pharmaceutical Design was introduced in 1995 with the assistance of Dr. William A. Banks, who is the current Editor-in-Chief serving since 1995.
Scopus CiteScore Metrics: 2.32

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