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"Current Pharmaceutical Design is a necessity for scientists working in the multidisciplinary fields encompassing the areas of drug design and discovery."

Annette M. Doherty
Pfizer Global R&D France

Forthcoming Special Issues

An Approach to the Theoretical and Experimental Design of Fused Compounds in the Treatment of Mental and Motor Dysfunctions


Guest Editor(s): Eduardo Sobarzo-Sánchez
Tentative Publication Date: October, 2018
Submit Abstract via Email Download Description
Special Issues - In-Press

Recent advances towards the treatment of depressive disorders


Guest Editor(s): Kefeng Li, Xu Wang
Download Description
Published Special Issues

Managing strategies for diverse diseases: Challenges from bench to bedside in successful drug discovery and development


Current Pharmaceutical Design, Volume 23, Number 11
Guest Editor(s): Mohammad Amjad Kamal, Nigel H. Greig

Authors' Comments
Thank you for the high quality of your services and it was such a pleasure and learning experience working with you.

Menglin Li
(School of Basic Medical Science, Beijing University of Chinese Medicine, Beijing 100029, China)


Current Pharmaceutical Design

,

Volume 24

-

Number 15



Review Article



Review Article

Technetium-99m-based Radiopharmaceuticals in Sentinel Lymph Node Biopsy: Gynecologic Oncology Perspective

, 24(15): 1652 - 1675

Kamil Zalewski*, Malgorzata Benke, Bartlomiej Mirocha, Jakub Radziszewski, Magdalena Chechlinska and Magdalena Kowalewska


DOI: 10.2174/1381612824666180515122150


Review Article



Research Article

Carboxymethyl-hexanoyl Chitosan Nanodroplets for Ultrasonic Imaging and Drug Delivery to Tumor

, 24(15): 1682 - 1688

Yu Jinsui, Situ Bing, Luo Muhua, Li Yue, Liao Jianyi, Du Meng, Cai Kuan, Yang Chaopin, Zhang Hui and Chen Zhiyi*


DOI: 10.2174/1381612824666180515122836


Research Article

Comparative Assay of 2D and 3D Cell Culture Models: Proliferation, Gene Expression and Anticancer Drug Response

, 24(15): 1689 - 1694

Aline G. Souza*, Isaura Beatriz. B. Silva, Esther Campos-Fernandez, Leticia S. Barcelos, Jessica Brito Souza, Karina Marangoni, Luiz R. Goulart and Vivian Alonso-Goulart


DOI: 10.2174/1381612824666180404152304


Research Article

Diabetes-Related Neurological Implications and Pharmacogenomics

, 24(15): 1695 - 1710

Camilo Andrés Rojas-Carranza, Rosa Helena Bustos-Cruz*, Carmen Juliana Pino-Pinzón, Yeimy Viviana Ariza-Marquez, Rosa Margarita Gómez-Bello and Marisa Cañadas-Garre


DOI: 10.2174/1381612823666170317165350


Research Article



Research Article

Nanodiagnostics and Nanodelivery Applications in Genetic Alterations

, 24(15): 1717 - 1726

Maria Sofia Falzarano, Cristina Flesia, Roberta Cavalli , Caterina Guiot and Alessandra Ferlini*


DOI: 10.2174/1381612824666180110151318


Current Pharmaceutical Design, Volume 24 (2018) - Number 18


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 24 (2018) - Number 17


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Targeted Delivery of siRNA Therapeutics using Ligand Mediated Biodegradable Polymeric Nanocarriers


Hong Seo Jin, Cho Kye Soo, Ahn Min Hye, Pal Sukdeb, Choung Pill-Hoon, Jaiprakash Sangshetti and Rohidas B. Arote*


View Abstract View on PubMed


Targeted Liposomes for siRNA Delivery to Cancer


Josimar O. Eloy, Raquel Petrilli, Giovanni Loureiro Raspantini and Robert J. Lee*


View Abstract View on PubMed



Circadian Rhythm and Melatonin in the Treatment of Depression


Senthil Kumaran Satyanarayanan, Huanxing Su, Yi-Wen Lin and Kuan-Pin Su*


View Abstract View on PubMed




Current Rapid-Onset Antidepressants and Related Animal Models


Kuo Yan, Yi-Bing Chen , Jia-Rong Wu, Kuang-Dai Li and Yuan-Lu Cui*


View Abstract View on PubMed



Rapid-Acting Antidepressants


Jeffrey M. Witkin*, Daniel E. Knutson, Gabriel J. Rodriguez and Samuel Shi


View Abstract View on PubMed


Abstracts Ahead of Print

Emerging and alternative therapies for Parkinson disease: an updated review


Atul Kabra, Rohit Sharma, Ruchika Kabra and Uttam Singh Baghel*


View Abstract


Cordycepin modulates body weight by reducing prolactin via an adenosine A1 receptor


Yuan Li, Yan Li, Xueyan Wang, Hongyue Xu, Chao Wang, Yanan An, Wenjing Luan, Xuefei Wang, Shulin Li, Fangxue Ma, Lihui Ni, Mingyuan Liu, Xudong Tang* and Lu Yu*


View Abstract


Thioredoxin as a therapeutic target in cerebral ischemia


Xian-Si Zeng*, Wen-Shuo Geng, Lei Chen and Jin-Jing Jia*


View Abstract


A comparison of proliferation of human mesenchymal stem cells derived from adipose tissue treated with human full-length amelogenin and C-terminal amelogenin peptide


Kazuyo Ando, Ryo Kunimatsu, Tetsuya Awada, Yuki Yoshimi, Yuji Tsuka, Keisuke Sumi, Kayo Horie, Takaharu Abe, Kengo Nakajima and Kotaro Tanimoto


View Abstract




The possible impact of hyperuricemia on serum soluble receptor for advanced glycation end products (sRAGE) levels in teenagers: a case control study.


M Lemiesz*, E Tenderenda-Banasiuk, D Sosnowska , A Rybi-Szuminska, J Storonowicz , T Lemiesz and A Wasilewska


View Abstract



The Development of Pharmacophore Modeling: Generation and Recent Applications in Drug Discovery


Xin Lu , Hongyu Yang, Yao Chen, Qi Li , Si-yu He, Xueyang Jiang, Feng Feng, Wei Qu and Haopeng Sun *


View Abstract


Improvement of stability of tea polyphenols: a review


Bo Sun, Weijun Wang, Zhibin He, Min Zhang, Fangong Kong, Mohini Sain and Yonghao Ni*


View Abstract


Editor's Choice

Diabetes-Related Neurological Implications and Pharmacogenomics

, 2018; 24(15): 1695 - 1710

Camilo Andres Rojas-Carranza, Rosa Helena Bustos-Cruz*, Carmen Juliana Pino-Pinzon, Yeimy Viviana Ariza-Marquez, Rosa Margarita Gomez-Bello and Marisa Canadas-Garre


DOI: 10.2174/1381612823666170317165350



The Role of Inflammation in Neurological Disorders

, 2018; 24(14): 1485 - 1501

Diana Degan, Raffaele Ornello, Cindy Tiseo, Antonio Carolei, Simona Sacco and Francesca Pistoia*


DOI: 10.2174/1381612824666180327170632



Peptide Mediated Brain Delivery of Nano- and Submicroparticles: A Synergistic Approach

, 2018; 24(13): 1366 - 1376

Mark McCully, Macarena Sanchez-Navarro , Meritxell Teixido* and Ernest Giralt*


DOI: 10.2174/1381612824666171201115126




Immunotheraphy in Allergic Diseases

, 2018; 24(11): 1174 - 1194

Albert Roger, Maria Basagana, Aina Teniente-Serra, Nathalie Depreux, Yanina Jurgens, Clara Padro, Sira Miquel, Carolina Elduque and Eva M. Martinez-Caceres*


DOI: 10.2174/1381612824666180116094048



Lactoferrin and Peptide-derivatives: Antimicrobial Agents with Potential Use in Nonspecific Immunity Modulation

, 2018; 24(10): 1067 - 1078

Maria Elisa Drago-Serrano, Rafael Campos-Rodriguez, Julio Cesar Carrero* and Mireya de la Garza*


DOI: 10.2174/1381612824666180327155929




The Modification and Design of Antimicrobial Peptide

, 2018; 24(8): 904 - 910

Yidan Gao, Hengtong Fang, Lu Fang, Dawei Liu, Jinsong Liu, Menghan Su, Zhi Fang, Wenzhi Ren* and Huping Jiao*


DOI: 10.2174/1381612824666180213130318



Current Status of Molecular Imaging in Inflammatory and Autoimmune Disorders

, 2018; 24(7): 743 - 753

Alberto Signore*, Kelly Luz Anzola, Sveva Auletta, Michela Varani, Agnese Petitti, Marta Pacilio, Filippo Galli and Chiara Lauri


DOI: 10.2174/1381612824666180130115153




Open Access Articles

Defense Mechanisms Against Acid Exposure by Dental Enamel Formation, Saliva and Pancreatic Juice Production

, 2018; 24(18): 2012 - 2022

Robert Racz, Akos Nagy, Zoltan Rakonczay , Erika Katalin Dunavari, Gabor Gerber and Gabor Varga*




Peptide Mediated Brain Delivery of Nano- and Submicroparticles: A Synergistic Approach

, 2018; 24(13): 1366 - 1376

Mark McCully, Macarena Sanchez-Navarro , Meritxell Teixido* and Ernest Giralt*




Development of Peptide Vaccines in Dengue

, 2018; 24(11): 1157 - 1173

Kavita Reginald, Yanqi Chan, Magdalena Plebanski and Chit Laa Poh*





Virtual Screening and Statistical Analysis in the Design of New Caffeine Analogues Molecules with Potential Epithelial Anticancer Activity

, 2018; 24(5): 576 - 594

Josivan da Silva Costa*, Karina da Silva Lopes Costa, Josiane Viana Cruz, Ryan da Silva Ramos, Luciane Barros Silva, Davi Do Socorro Barros Brasil, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos and Williams Jorge da Cruz Macedo







Pivotal Roles of Interleukin-17 as the Epicenter of Bone Loss Diseases

, 2017; 23(41): 6302 - 6309

Chongshan Liao, Chengfei Zhang and Yanqi Yang*





IGF-1 as a Drug for Preterm Infants: A Step-Wise Clinical Development

, 2017; 23(38): 5964 - 5970

Ann Hellstrom*, David Ley, Boubou Hallberg, Chatarina Lofqvist, Ingrid Hansen-Pupp, Luca A. Ramenghi, Jan Borg, Lois E. H. Smith and Anna-Lena Hard




A Special Focus on Selexipag - Treatment of Pulmonary Arterial Hypertension

, 2017; 23(34): 5191 - 5199

Louise M. Sorensen, Markus Wehland, Marcus Kruger, Ulf Simonsen, Mohamed Z. Nassef, Manfred Infanger and Daniela Grimm*




A Review of Chinese Herbal Medicine for the Treatment of Chronic Heart Failure

, 2017; 23(34): 5115 - 5124

Yong Wang*, Qiyan Wang, Chun Li, Linghui Lu, Qian Zhang, Ruixin Zhu* and Wei Wang*





DNA Base Excision Repair: The Achilles' Heel of Tumour Cells and their Microenvironment?

, 2017; 23(32): 4758 - 4772

Mattia Poletto *, Arnaud J. Legrand * and Grigory L. Dianov*





Most Cited Articles

Autism: Pathophysiology and Promising Herbal Remedies

, 2016; 22(3): 277-285.

Mahmoud Bahmani, Amir Sarrafchi, Hedayatollah Shirzad and Mahmoud Rafieian-Kopaei


DOI: 10.2174/1381612822666151112151529


Air Pollution Exposure and Blood Pressure: An Updated Review of the Literature

, 2016; 22(1): 28-51.

Paolo Giorgini, Paolo Di Giosia, Davide Grassi, Melvyn Rubenfire, Robert D. Brook and Claudio Ferri


DOI: 10.2174/1381612822666151109111712



Circulating microRNAs in Hepatocellular Carcinoma: Potential Diagnostic and Prognostic Biomarkers

, 2016; 22(34): 5257-5269.

Hamid Reza Mirzaei, Amirhossein Sahebkar, Mohsen Mohammadi, Reza Yari, Hossein Salehi, Mohammad Hasan Jafari, Afshin Namdar, Ehsan Khabazian, Mahmoud Reza Jaafari and Hamed Mirzaei


DOI: 10.2174/1381612822666160303110838


The potential for circulating microRNAs in the diagnosis of myocardial infarction: a novel approach to disease diagnosis and treatment

, 2016; 22(3): 397-403.

Sharareh Gholamin, Alireza Pasdar, Mohammad Sadegh Khorrami, Hamed Mirzaei, Hamid Reza Mirzaei, Rasoul Salehi, Gordon A. Ferns, Majid Ghayour-Mobarhan and Amir Avan


DOI: 10.2174/1381612822666151112151924


Computer Aided Drug Design: Success and Limitations

, 2016; 22(5): 572-581.

Mohammad Hassan Baig, Khurshid Ahmad, Sudeep Roy, Jalaluddin Mohammad Ashraf, Mohd Adil, Mohammad Haris Siddiqui, Saif Khan, Mohammad Amjad Kamal, Ivo Provazník and Inho Choi


DOI: 10.2174/1381612822666151125000550


Herba Epimedii: An Ancient Chinese Herbal Medicine in the Prevention and Treatment of Osteoporosis

, 2016; 22(3): 328-349.

Lili Wang, Yu Li, Yubo Guo, Rufeng Ma, Min Fu, Jianzhao Niu, Sihua Gao and Dongwei Zhang


DOI: 10.2174/1381612822666151112145907


From Fangs to Pharmacology: The Future of Snakebite Envenoming Therapy

, 2016; 22(34): 5270-5293.

Andreas H. Laustsen, Mikael Engmark, Christina Milbo, Jónas Johannesen, Bruno Lomonte, José María Gutiérrez and Brian Lohse


DOI: 10.2174/1381612822666160623073438




Most Accessed Articles

Recent Advances in Cancer Therapy: An Overview

, 2010; 16(1): 3-10.

A. Urruticoechea, R. Alemany, J. Balart, A. Villanueva, F. Vinals and G. Capella


DOI: 10.2174/138161210789941847




Polyphenols: Potential Use in the Prevention and Treatment of Cardiovascular Diseases

, 2018; 24(2): 239-258.

Rosaria Vincenza Giglio, Angelo Maria Patti, Arrigo F.G. Cicero, Giuseppe Lippi, Manfredi Rizzo*, Peter P. Toth and Maciej Banach


DOI: 10.2174/1381612824666180130112652



The Transport Mechanism of Extracellular Vesicles at the Blood-Brain Barrier

, 2017; 23(40): 6206-6214.

Junichi Matsumoto, Tessandra Stewart, William A. Banks and Jing Zhang*


DOI: 10.2174/1381612823666170913164738


A Critical Review of the Antipsychotic Effects of Cannabidiol: 30 Years of a Translational Investigation

, 2012; 18(32): 5131-5140.

Antonio Waldo Zuardi, Jose Alexandre S. Crippa, Jaime E.C. Hallak, Sagnik Bhattacharyya, Zerrin Atakan, Rocio Martin-Santos, Philip K. McGuire and Francisco Silveira Guimaraes


DOI: 10.2174/138161212802884681




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