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Current Pharmaceutical Design

Volume 28, 46 Issues, 2022
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth reviews/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

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Volume 28

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Number 8



Review Article

Therapeutic Application of Microsponges-based Drug Delivery Systems

, 28(8): 595 - 608

Mahfoozur Rahman, Waleed H. Almalki, Sunil K. Panda, Aman K. Das, Saad Alghamdi, Kriti Soni, Abdul Hafeez, Mayank Handa, Sarwar Beg* and Ziyaur Rahman*


DOI: 10.2174/1381612828666220118121536


Review Article

Hydrogels for Modified-release Drug Delivery Systems

, 28(8): 609 - 618

Aleksandra Zielińska, Piotr Eder, Lucas Rannier, Juliana C. Cardoso, Patrícia Severino, Amélia M. Silva and Eliana B. Souto*


DOI: 10.2174/1381612828666211230114755


Review Article



Review Article

Plant based Bioavailability Enhancers

, 28(8): 642 - 654

Sweta Patel, Shruti Chopra, Simran Chaurasia and Maryam Sarwat*


DOI: 10.2174/1381612828666220112141355


General Research Article

Evaluation of Gastroprotective Activity of Linoleic Acid on Gastric Ulcer in a Mice Model

, 28(8): 655 - 660

José L.R. Martins*, Dayane M. Silva, Emerson H. Gomes, Samuel A. Fava, Murilo F. Carvalho, Isaac Y.L. Macedo, Eric S. Gil, Paulo C. Ghedini, Fábio F. Rocha, Osmar N. Silva*, James O. Fajemiroye, Emerith M.H. Pinto and Elson A. Costa


DOI: 10.2174/1381612826666200908144053


General Research Article

S-Allylcysteine (SAC) Exerts Renoprotective Effects via Regulation of TGF- β1/Smad3 Pathway Mediated Matrix Remodeling in Chronic Renal Failure

, 28(8): 661 - 670

Ramkumar Samynathan, Umadevi Subramanian, Baskar Venkidasamy, Mohammad Ali Shariati, Ill-Min Chung and Muthu Thiruvengadam*


DOI: 10.2174/1381612828666220401114301


General Research Article

Protective Effect of Panax Notoginseng Saponins on Apolipoprotein-E-deficient Atherosclerosis-prone Mice

, 28(8): 671 - 677

He Yang, Zuodong Liu, Xiangka Hu, Xiaojuan Liu, Liuming Gui, Zengxiaorui Cai and Chunmei Dai*


DOI: 10.2174/1381612828666220128104636


Current Pharmaceutical Design, Volume 28 (2022) - Number 10


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 28 (2022) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print











Abstracts Ahead of Print

HNF1A-AS1:A tumor-associated long non-coding RNA


Yuling Liu, Fangnan Zhao, Fangshun Tan, Lu Tang, Zhuoying Du, Jie Mou, Gang Zhou* and Chengfu Yuan*


DOI: 10.2174/1381612828666220520113846
View Abstract



Review on Artificial Intelligence Based Ophthalmic Application


Sudhakar Kothandan, Arun Radhakrishana and Gowthamarajan Kuppusamy*


DOI: 10.2174/1381612828666220520112240
View Abstract


Immunopathogenesis and immunogenetic variants in COVID-19


Pakorn Sagulkoo, Kitiporn Plaimas*, Apichat Suratanee, Andrea Name Colado Simão, Edna Maria Vissoci Reiche and Michael Maes*


DOI: 10.2174/1381612828666220519150821
View Abstract



Immune Checkpoint Inhibitor-Induced Thyroid Disorders: a Single Center Experience


Armando Patrizio, Poupak Fallahi*, Alessandro Antonelli and Silvia Martina Ferrari


DOI: 10.2174/1381612828666220518151509
View Abstract




Alginate-based Composites Microspheres: Preparations and Applications for Bone Tissue Engineering


Jayachandran Venkatesan*, Sesha Subramanian Murugan, Pandurang AD, Yashaswini DGV and Gi Hun Seong*


DOI: 10.2174/1381612828666220518142911
View Abstract


Docosahexaenoic acid ester of phloridzin reduces inflammation and insulin resistance via AMPK


Jingqing Chen, Zhenlong Wu, Jin Wang, Xuemeng Si, Rui Zhang, Tianqi Sun, Qiaoyan Dong, Wenqing Wu* and Yefeng Qiu*


DOI: 10.2174/1381612828666220518102440
View Abstract


Published Contents

Editor's Choice





Outer Membrane Vesicles of Bordetella pertussis Encapsulated into Sodium Alginate Nanoparticles as Novel Vaccine Delivery System

, 2021; 27(42): 4341 - 4354

Abbas Rami, Fatemeh Kazemi-Lomedasht, Ali Mirjalili, Mojtaba Noofeli, Fereshteh Shahcheraghi* and Naser M. Dounighi*


DOI: 10.2174/1381612827666210907154715



Anticholinergic Exposure in Elderly Complex Chronic Patients: A Cross-Sectional Study

, 2021; 27(40): 4186 - 4194

Ángela Tristancho-Pérez, Ángela Villalba-Moreno, María D. Santos-Rubio, María D. López-Malo, Bernardo Santos-Ramos and Susana Sánchez-Fidalgo*


DOI: 10.2174/1381612827666210830164054






Hypertension in Pregnancy: Unanswered Questions

, 2021; 27(36): 3795 - 3803

Vasilios Papademetriou *, Konstantinos Stavropoulos , Dimitrios Patoulias, Christodoulos Papadopoulos, Kerpiniotis Georgios, Maria Toumpourleka and Alexandros Sachinidis


DOI: 10.2174/1381612827666210830091652



Open Access Articles

The Pathogenic Subpopulation of Th17 Cells in Obesity

, 2021; 27(37): 3924 - 3938

Natalia Todosenko, Maria Vulf*, Kristina Yurova, Daria Skuratovskaia, Olga Khaziakhmatova, Natalia Gazatova, Olga Melashchenko, Olga Urazova and Larisa Litvinova





Exosome Limitations in the Treatment of Inflammatory Diseases

, 2021; 27(28): 3105 - 3121

Daria Skuratovskaia*, Maria Vulf, Olga Khaziakhmatova, Vladimir Malashchenko, Aleksandra Komar, Egor Shunkin, Natalia Gazatova and Larisa Litvinova




Marine Bioactive Peptides in Supplements and Functional Foods - A Commercial Perspective

, 2021; 27(11): 1353 - 1364

Ragnhild Dragøy Whitaker*, Themis Altintzoglou, Kjersti Lian and Estefania Noriega Fernandez








A New Look at an Old Drug: Cumulative Effects of Low Ribavirin Doses in Amphetamine-Sensitized Rats

, 2020; 26(31): 3884 - 3894

Branka Petković*, Srđan Kesić, Slavica Ristić, Željko Pavković, Jelena Podgorac, Gordana Stojadinović and Vesna Pešić





γ-Aminobutyric Acid and Derivatives Reduce the Incidence of Acute Pain after Herpes Zoster - A Systematic Review and Meta-analysis

, 2020; 26(25): 3026 - 3038

Wuttapon Sadaeng, Katalin Márta, Péter Mátrai, Péter Hegyi, Barbara Tóth, Balázs Németh, László M. Czumbel, Thanyaporn Sang-Ngoen, Zoltán Gyöngyi, Gábor Varga*, Péter Révész, István Szanyi, Kázmér Karádi and Gábor Gerber




Effects of Chlorine Dioxide on Oral Hygiene - A Systematic Review and Meta-analysis

, 2020; 26(25): 3015 - 3025

Beáta Kerémi, Katalin Márta, Kornélia Farkas, László M. Czumbel, Barbara Tóth, Zsolt Szakács, Dezső Csupor, József Czimmer, Zoltán Rumbus, Péter Révész, Adrienn Németh, Gábor Gerber, Péter Hegyi and Gábor Varga*






Circulating MicroRNAs and Blood-Brain-Barrier Function in Breast Cancer Metastasis

, 2020; 26(13): 1417 - 1427

Carolin J. Curtaz, Constanze Schmitt, Kinga G. Blecharz-Lang, Norbert Roewer, Achim Wöckel and Malgorzata Burek*





Most Cited Articles

Review Article

Pollution, toxicity and carcinogenicity of organic dyes and their catalytic bio-remediation

, 2019; 25(34): 3645-3663.

Muhammad Ismail, Kalsoom Akhtar, M.I. Khan, Tahseen Kamal, Murad A. Khan, Abdullah M. Asiri, Jongchul Seo and Sher B. Khan*


DOI: 10.2174/1381612825666191021142026


General Review Article

Long non-coding RNAs as epigenetic regulators in cancer

, 2019; 25(33): 3563-3577.

Asma Vafadar, Zahra Shabaninejad, Ahmad Movahedpour, Soheila Mohammadi, Sima Fathullahzadeh, Hamid R. Mirzaei, Afshin Namdar, Amir Savardashtaki* and Hamed Mirzaei*


DOI: 10.2174/1381612825666190830161528


Review Article

Synthesis of silver nanoparticles and their biomedical applications a comprehensive review

, 2019; 25(24): 2650-2660.

Rajasree Shanmuganathan, Indira Karuppusamy, Muthupandian Saravanan, Harshiny Muthukumar, Kumar Ponnuchamy, Vijayan Sri Ramkumar and Arivalagan Pugazhendhi*


DOI: 10.2174/1381612825666190708185506


Review Article

Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning

, 2019; 25(33): 3519-3535.

Md. Tanvir Kabir, Md. Sahab Uddin*, Mst. Marium Begum, Shanmugam Thangapandiyan, Md. Sohanur Rahman, Lotfi Aleya, Bijo Mathew, Muniruddin Ahmed, George E. Barreto and Ghulam Md. Ashraf


DOI: 10.2174/1381612825666191008103141


Review Article

NMDA receptor antagonists: Repositioning of memantine as a multitargeting agent for Alzheimer's therapy

, 2019; 25(33): 3506-3518.

Md. Tanvir Kabir, Mohammad A. Sufian, Md. Sahab Uddin*, Mst. Marium Begum, Shammi Akhter, Ariful Islam, Bijo Mathew, Md. Siddiqul Islam, Md. Shah Amran and Ghulam Md. Ashraf*


DOI: 10.2174/1381612825666191011102444


Review Article

Alginate nanoparticles for drug delivery and targeting

, 2019; 25(11): 1312-1334.

Patricia Severino, Classius F. da Silva, Luciana N. Andrade, Daniele de Lima Oliveira, Joana Campos and Eliana B. Souto*


DOI: 10.2174/1381612825666190425163424



Review Article

Emerging potential of naturally occurring autophagy modulators against neurodegeneration

, 2020; 26(7): 772-779.

Md. Ataur Rahman*, Md Rezanur Rahman, Toyfiquz Zaman, Md. Sahab Uddin, Rokibul Islam, Mohamed M. Abdel-Daim and Hyewhon Rhim*


DOI: 10.2174/1381612826666200107142541


Review Article

Composition and potential health benefits of pomegranate: A review

, 2019; 25(16): 1817-1827.

Vesna Vučić*, Milkica Grabež, Armen Trchounian and Aleksandra Arsić


DOI: 10.2174/1381612825666190708183941


Review Article

Metal/metal oxide nanoparticles: Toxicity, applications, and future prospects

, 2019; 25(37): 4013-4029.

Ratiram G. Chaudhary*, Ganesh S. Bhusari, Ashish D. Tiple, Alok R. Rai, Subhash R. Somkuvar, Ajay K. Potbhare, Trimurti L. Lambat, Prashant P. Ingle and Ahmed A. Abdala*


DOI: 10.2174/1381612825666191111091326



General Review Article

Ethnobotany, phytochemistry and traditional uses of curcuma spp. and pharmacological profile of two important species (C. longa and C. zedoaria): A Review

, 2019; 25(8): 871-935.

Zahra Ayati, Mahin Ramezani , Mohammad Sadegh Amiri, Ali Tafazoli Moghadam, Hoda Rahimi, Aref Abdollahzade, Amirhossein Sahebkar * and Seyed Ahmad Emami *


DOI: 10.2174/1381612825666190402163940


Review Article

Extracellular vesicles as drug delivery systems - Methods of production and potential therapeutic applications

, 2019; 25(2): 132-154.

Magdalena Surman, Anna Drożdż, Ewa Stępień and Małgorzata Przybyło*


DOI: 10.2174/1381612825666190306153318





Most Accessed Articles

Natural Agents Modulating ACE-2: A Review of Compounds with Potential against SARS-CoV-2 Infections

, 2021; 27(13): 1588-1596.

Gasparotto Junior, Arquimedes; Lima Tolouei, Sara Emilia; dos Reis Livero, Francislaine Aparecida; Gasparotto, Francielli; Boeing, Thaise; de Souza, Priscila


DOI: 10.2174/1381612827666210114150607


Anti-Neuroinflammatory Potential of Polyphenols by Inhibiting NF-kappa B to Halt Alzheimer's Disease

, 2021; 27(3): 402-414.

Uddin, Md Sahab; Hasana, Sharifa; Ahmad, Jamil; Hossain, Md Farhad; Rahman, Md Mosiqur; Behl, Tapan; Rauf, Abdur; Ahmad, Ausaf; Hafeez, Abdul; Perveen, Asma; Ashraf, Ghulam Md


DOI: 10.2174/1381612826666201118092422



Hepatoprotective Effects of Resveratrol in Non-Alcoholic Fatty Live Disease

, 2021; 27(22): 2558-2570.

Tejada, Silvia; Capo, Xavier; Mascaro, Catalina M.; Monserrat-Mesquida, Margalida; Quetglas-Llabres, M. Magdalena; Pons, Antoni; Tur, Josep A.; Sureda, Antoni


DOI: 10.2174/1381612826666200417165801


Exploring Potential of Alkaloidal Phytochemicals Targeting Neuroinflammatory Signaling of Alzheimer's Disease

, 2021; 27(3): 357-366.

Uddin, Md Sahab; Kabir, Md Tanvir; Al Mamun, Abdullah; Behl, Tapan; Mansouri, Rasha A.; Aloqbi, Akram Ahmed; Perveen, Asma; Hafeez, Abdul; Ashraf, Ghulam Md


DOI: 10.2174/1381612826666200531151004



Phytosterols: Targeting Neuroinflammation in Neurodegeneration

, 2021; 27(3): 383-401.

Dash, Raju; Mitra, Sarmistha; Ali, Md Chayan; Oktaviani, Diyah Fatimah; Hannan, Md Abdul; Choi, Sung Min; Moon, Il Soo


DOI: 10.2174/1381612826666200628022812





Repurposing Drugs for the Management of Patients with Confirmed Coronavirus Disease 2019 (COVID-19)

, 2021; 27(1): 115-126.

Wietzikoski Lovato, Evellyn Claudia; Barboza, Lorena Neris; Wietzikoski, Samantha; Vasques de Souza, Amanda Nascimento; Auth, Pablo Alvarez; Gasparotto Junior, Arquimedes; dos Reis Livero, Francislaine Aparecida


DOI: 10.2174/1381612826666200707121636


miRNAs in SARS-CoV 2: A Spoke in the Wheel of Pathogenesis

, 2021; 27(13): 1628-1641.

Satyam, Rohit; Bhardwaj, Tulika; Goel, Sachin; Jha, Niraj Kumar; Jha, Saurabh Kumar; Nand, Parma; Ruokolainen, Janne; Kamal, Mohammad Amjad; Kesari, Kavindra Kumar


DOI: 10.2174/1381612826999201001200529







Editor-in-Chief

graphic
Alessandro Antonelli
(12,288 citations)
Department of Clinical and Experimental Medicine
Laboratory of Primary Human Cells
University of Pisa
Pisa
(Italy)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

graphic
Andrew V. Schally
(USA)

COPE Compliant

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Journal History

Current Pharmaceutical Design was introduced in 1995. Prof. Alessandro Antonelli serves as the Editor-in-Chief of the journal.

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