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Current Pharmaceutical Design

Volume 26, 46 Issues, 2020
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

,

Volume 26

-

Number 33



Editorial



Review Article

Catechins as Model Bioactive Compounds for Biomedical Applications

, 26(33): 4032 - 4047

Adriana N. dos Santos, Tatiana R. de L. Nascimento, Brenna L. C. Gondim, Marilia M. A. C. Velo, Renaly I. de A. Rêgo, José R. do C. Neto, Juliana R. Machado, Marcos V. da Silva, Helvia W. C. de Araújo, Maria G. Fonseca and Lúcio R. C. Castellano*


DOI: 10.2174/1381612826666200603124418


Review Article

Therapeutic Potential of Melaleuca alternifolia Essential Oil in New Drug Delivery Systems

, 26(33): 4048 - 4055

Karoll M. A. de Assis, Renaly I. de A. Rêgo, Demis F. de Melo, Laryssa M. da Silva, João A. Oshiro- Júnior, Fábio R. Formiga, Vinícius C. Pires, Ádley A. N. de Lima, Attilio Converti* and Bolívar P. G. de L. Damasceno


DOI: 10.2174/1381612826666200305124041


Review Article

Annona Genus: Traditional Uses, Phytochemistry and Biological Activities

, 26(33): 4056 - 4091

Debora O. D. Leite, Carla de F. A. Nonato, Cicera J. Camilo, Natália K. G. de Carvalho , Mário G. L. A. da Nóbrega, Rafael C. Pereira and José G. M. da Costa*


DOI: 10.2174/1381612826666200325094422


Review Article

Larvicidal Activity of Essential Oils Against Aedes aegypti (Diptera: Culicidae)

, 26(33): 4092 - 4111

Mikael A. de Souza, Larissa da Silva, Maria A. C. dos Santos, Márcia J. F. Macêdo, Luiz J. Lacerda-Neto, Henrique D. M. Coutinho*, Lígia C. C. de Oliveira and Francisco A. B. Cunha


DOI: 10.2174/1381612826666200806100500


Review Article

Bioprospecting of Nitrogenous Heterocyclic Scaffolds with Potential Action for Neglected Parasitosis: A Review

, 26(33): 4112 - 4150

Sonaly L. Albino, Jamire M. da Silva, Michelangela S. de C. Nobre, Yvnni M. S. de M. e Silva, Mirelly B. Santos, Rodrigo S. A. de Araújo, Maria do C. A. de Lima, Martine Schmitt and Ricardo O. de Moura*


DOI: 10.2174/1381612826666200701160904


Review Article

In silico Exploration of Bioactive Phytochemicals Against Neurodegenerative Diseases Via Inhibition of Cholinesterases

, 26(33): 4151 - 4162

Fawzi Mahomoodally*, Hassan H. Abdallah, Shanoo Suroowan, Sharmeen Jugreet, Yansheng Zhang and Xuebo Hu


DOI: 10.2174/1381612826666200316125517


Review Article

Physicochemical Characterization of Bioactive Compounds in Nanocarriers

, 26(33): 4163 - 4173

Rafaella M. Barros, Maísa S. de Oliveira, Kammila M. N. Costa, Mariana R. Sato, Karen L. M. Santos, Bolívar P. G. de L. Damasceno, Teresa Cuberes and Joáo A. Oshiro-Junior*


DOI: 10.2174/1381612826666200310144533


Current Pharmaceutical Design, Volume 26 (2020) - Number 38


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 26 (2020) - Number 37


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 26 (2020) - Number 36


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 26 (2020) - Number 35


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 26 (2020) - Number 34


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print






Significance of green synthetic chemistry from a pharmaceutical perspective


Haseeb Ahsan, Salman Ul Islam, Muhammad Bilal Ahmed, Young Sup Lee and Jong Kyung Sonn*


DOI: 10.2174/1381612826666200928160851
View Abstract


Medicinal Plants and Bioactive Compounds for Diabetes Management: Important Advances for Drug Discovery


Kondeti Ramudu Shanmugam*, Bhasha Shanmugam, Gangigunta Venkatasubbaiah, Sahukari Ravi and Kesireddy Sathyavelu Reddy


DOI: 10.2174/1381612826666200928160357
View Abstract


Berberine Exerts Anti-cancer Activity by Modulating Adenosine Monophosphate-Activated Protein Kinase (AMPK) and the Phosphatidylinositol 3-Kinase/Protein Kinase B (PI3K/AKT) Signaling Pathways


Jin Huang, Wei Feng, Shanshan Li, Huiling Tang, Siru Qin, Wei Li, Yinan Gong, Yuxin Fang, Yangyang Liu, Shenjun Wang, Yi Guo, Zhifang Xu* and Qian Shen


DOI: 10.2174/1381612826666200928155728
View Abstract


The Potential Role of Carbon Nanoparticles in Lymph Node Tracing, Recurrent Laryngeal Nerve Identification and Parathyroid Preservation During Thyroid Surgery: A Systematic Review


Eleftherios Spartalis*, Alexios Giannakodimos, Dimitrios I. Athanasiadis, Dimosthenis Chrysikos, Stavroula A. Paschou, Dimitrios Schizas, Nikolaos Patelis, Themistoklis Papasilekas, Konstantinos Themistoklis, Michael Spartalis, Theodore Troupis and Nikolaos Nikiteas


DOI: 10.2174/1381612826666200922154824
View Abstract View on PubMed


Beneficiary and Adverse Effects of Phytoestrogens: A Potential Constituent of Plant-Based Diet


Sridevi Vaadala, Naveen Ponneri, Venkat Shashank Karnam, Ramachandra Reddy Pamuru* and Mohammed Arifullah


DOI: 10.2174/1381612826999200917154747
View Abstract View on PubMed


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Catechins as Model Bioactive Compounds for Biomedical Applications

, 2020; 26(33): 4032 - 4047

Adriana N. dos Santos, Tatiana R. de L. Nascimento, Brenna L. C. Gondim, Marilia M. A. C. Velo, Renaly I. de A. Rêgo, José R. do C. Neto, Juliana R. Machado, Marcos V. da Silva, Helvia W. C. de Araújo, Maria G. Fonseca and Lúcio R. C. Castellano*


DOI: 10.2174/1381612826666200603124418




Precision Medicine Approach in Prostate Cancer

, 2020; 26(31): 3783 - 3798

Majid Assadi, Narges Jokar, Mojtaba Ghasemi, Iraj Nabipour, Ali Gholamrezanezhad and Hojjat Ahmadzadehfar*


DOI: 10.2174/1381612826666200218104921






Intranasal Lipid Particulate Drug Delivery Systems: An Update on Clinical Challenges and Biodistribution Studies of Cerebroactive Drugs in Alzheimer’s disease

, 2020; 26(27): 3281 - 3299

Deepshi Arora, Shailendra Bhatt , Manish Kumar, Hari D.C. Vattikonda, Yugam Taneja, Vishal Jain, Veenu Joshi and Chaitanya C. Gali*


DOI: 10.2174/1381612826666200331085854




Inflammatory Bowel Diseases: The Role of Gut Microbiota

, 2020; 26(25): 2951 - 2961

Cristiana De Musis, Lucia Granata, Marcello Dallio, Agnese Miranda, Antonietta G. Gravina and Marco Romano*


DOI: 10.2174/1381612826666200420144128



Artemia species: An Important Tool to Screen General Toxicity Samples

, 2020; 26(24): 2892 - 2908

Epole Ntungwe N, Eva M. Domínguez-Martín, Amilcar Roberto, Joana Tavares, Vera M. S. Isca, Paula Pereira, Maria-João Cebola and Patrícia Rijo*


DOI: 10.2174/1381612826666200406083035



Open Access Articles


Vaccinium myrtillus L. Fruits as a Novel Source of Phenolic Compounds with Health Benefits and Industrial Applications - A Review

, 2020; 26(16): 1917 - 1928

Tânia C. S. P. Pires , Cristina Caleja , Celestino Santos-Buelga , Lillian Barros* and Isabel C.F.R. Ferreira*






Circulating MicroRNAs and Blood-Brain-Barrier Function in Breast Cancer Metastasis

, 2020; 26(13): 1417 - 1427

Carolin J. Curtaz, Constanze Schmitt, Kinga G. Blecharz-Lang, Norbert Roewer, Achim Wöckel and Malgorzata Burek*




Role of microRNA and Long Non-Coding RNA in Hepatocellular Carcinoma

, 2020; 26(4): 415 - 428

Meenakshi Gupta, Kumari Chandan and Maryam Sarwat*




Burden and Prevention of HPV. Knowledge, Practices and Attitude Assessment Among Pre-Adolescents and their Parents in Italy

, 2020; 26(3): 326 - 342

Giancarlo Icardi, Claudio Costantino, Marcello Guido, Antonella Zizza, Vincenzo Restivo, Daniela Amicizia, Federico Tassinari, Maria Francesca Piazza, Chiara Paganino, Alessandra Casuccio, Francesco Vitale, Filippo Ansaldi and Cecilia Trucchi*




Specificity and Continuity of Schizophrenia and Bipolar Disorder: Relation to Biomarkers

, 2020; 26(2): 191 - 200

Yuji Yamada, Madoka Matsumoto, Kazuki Iijima and Tomiki Sumiyoshi*




RHPN1-AS1 Drives the Progression of Hepatocellular Carcinoma via Regulating miR-596/IGF2BP2 Axis

, 2019; 25(43): 4630 - 4640

Hu Fen, Zheng Hongmin, Wei Wei, Yang Chao, Yao Yang, Liu Bei and Sun Zhihua*




Probucol-induced hERG Channel Reduction can be Rescued by Matrine and Oxymatrine in vitro

, 2019; 25(43): 4606 - 4612

Yuan-Qi Shi, Pan Fan, Guo-Cui Zhang, Yu-Hao Zhang, Ming-Zhu Li, Fang Wang and Bao-Xin Li*





Nanomedicines to Treat Skin Pathologies with Natural Molecules

, 2019; 25(21): 2323 - 2337

Elisabetta Esposito*, Claudio Nastruzzi, Maddalena Sguizzato and Rita Cortesi




The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity

, 2019; 25(19): 2192 - 2198

Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*




Impact of Antioxidant Natural Compounds on the Thyroid Gland and Implication of the Keap1/Nrf2 Signaling Pathway

, 2019; 25(16): 1828 - 1846

Ana Paunkov, Dionysios V. Chartoumpekis, Panos G. Ziros, Niki Chondrogianni, Thomas W. Kensler and Gerasimos P. Sykiotis*






Most Cited Articles

General Review Article

Long non-coding RNAs as epigenetic regulators in cancer

, 2019; 25(33): 3563-3577.

Asma Vafadar, Zahra Shabaninejad, Ahmad Movahedpour, Soheila Mohammadi, Sima Fathullahzadeh, Hamid R. Mirzaei, Afshin Namdar, Amir Savardashtaki* and Hamed Mirzaei*


DOI: 10.2174/1381612825666190830161528


Review Article

NMDA receptor antagonists: Repositioning of memantine as a multitargeting agent for Alzheimer's therapy

, 2019; 25(33): 3506-3518.

Md. Tanvir Kabir, Mohammad A. Sufian, Md. Sahab Uddin*, Mst. Marium Begum, Shammi Akhter, Ariful Islam, Bijo Mathew, Md. Siddiqul Islam, Md. Shah Amran and Ghulam Md. Ashraf*


DOI: 10.2174/1381612825666191011102444


Review Article

Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning

, 2019; 25(33): 3519-3535.

Md. Tanvir Kabir, Md. Sahab Uddin*, Mst. Marium Begum, Shanmugam Thangapandiyan, Md. Sohanur Rahman, Lotfi Aleya, Bijo Mathew, Muniruddin Ahmed, George E. Barreto and Ghulam Md. Ashraf


DOI: 10.2174/1381612825666191008103141


Review Article

Synthesis of silver nanoparticles and their biomedical applications a comprehensive review

, 2019; 25(24): 2650-2660.

Rajasree Shanmuganathan, Indira Karuppusamy, Muthupandian Saravanan, Harshiny Muthukumar, Kumar Ponnuchamy, Vijayan Sri Ramkumar and Arivalagan Pugazhendhi*


DOI: 10.2174/1381612825666190708185506



Review Article

Emerging potential of naturally occurring autophagy modulators against neurodegeneration

, 2020; 26(7): 772-779.

Md. Ataur Rahman*, Md Rezanur Rahman, Toyfiquz Zaman, Md. Sahab Uddin, Rokibul Islam, Mohamed M. Abdel-Daim and Hyewhon Rhim*


DOI: 10.2174/1381612826666200107142541



Review Article

Expression profile of MicroRNA: An emerging hallmark of cancer

, 2019; 25(6): 642-653.

Uzma Zaheer, Muhammed Faheem, Ishtiaq Qadri, Nargis Begum, Hadi M. Yassine, Asmaa A. Al Thani and Shilu Mathew*


DOI: 10.2174/1386207322666190325122821


Review Article

Alginate nanoparticles for drug delivery and targeting

, 2019; 25(11): 1312-1334.

Patricia Severino, Classius F. da Silva, Luciana N. Andrade, Daniele de Lima Oliveira, Joana Campos and Eliana B. Souto*


DOI: 10.2174/1381612825666190425163424




Review Article

Novel pathways in the treatment of major depression: Focus on the glutamatergic system

, 2019; 25(4): 381-387.

Carmine Tomasetti , Chiara Montemitro, Annastasia L. C. Fiengo , Cristina Santone , Laura Orsolini , Alessandro Valchera, Alessandro Carano, Maurizio Pompili , Gianluca Serafini , Giampaolo Perna, Federica Vellante, Giovanni Martinotti, Massimo Di Giannantonio , Yong-Ku Kim, Marco D. Nicola , Antonello Bellomo, Antonio Ventriglio , Michele Fornaro and Domenico D. Berardis*


DOI: 10.2174/1381612825666190312102444


General Review Article

Ethnobotany, phytochemistry and traditional uses of curcuma spp. and pharmacological profile of two important species (C. longa and C. zedoaria): A Review

, 2019; 25(8): 871-935.

Zahra Ayati, Mahin Ramezani , Mohammad Sadegh Amiri, Ali Tafazoli Moghadam, Hoda Rahimi, Aref Abdollahzade, Amirhossein Sahebkar * and Seyed Ahmad Emami *


DOI: 10.2174/1381612825666190402163940


Review Article

Metal/metal oxide nanoparticles: Toxicity, applications, and future prospects

, 2019; 25(37): 4013-4029.

Ratiram G. Chaudhary*, Ganesh S. Bhusari, Ashish D. Tiple, Alok R. Rai, Subhash R. Somkuvar, Ajay K. Potbhare, Trimurti L. Lambat, Prashant P. Ingle and Ahmed A. Abdala*


DOI: 10.2174/1381612825666191111091326


Review Article

Recent advances of in-silico modeling of potent antagonists for the adenosine receptors

, 2019; 25(7): 750-773.

Pabitra Narayan Samanta, Supratik Kar* and Jerzy Leszczynski*


DOI: 10.2174/1381612825666190304123545



Most Accessed Articles

Signaling Pathways in Inflammation and Anti-inflammatory Therapies

, 2018; 24(14): 1449-1484.

Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*


DOI: 10.2174/1381612824666180327165604



The Clinical Applications of Curcumin: Current State and the Future

, 2013; 19(11): 2011-2031.

Xia Fan, Chun Zhang, Dong-bo Liu, Jun Yan and Hua-ping Liang


DOI: 10.2174/1381612811319110005


Histone Modifications, Stem Cells and Prostate Cancer

, 2014; 20(11): 1687-1697.

Francesco Crea, Pier-Luc Clermont, Antonello Mai and Cheryl D. Helgason


DOI: 10.2174/13816128113199990522


Therapeutic Potential of Agonists and Antagonists of A1, A2a, A2b and A3 Adenosine Receptors

, 2019; 25(26): 2892-2905.

Sumit Jamwal, Ashish Mittal, Puneet Kumar*, Dana M. Alhayani and Amal Al-Aboudi


DOI: 10.2174/1381612825666190716112319


The Therapeutic Target Hsp90 and Cancer Hallmarks

, 2013; 19(3): 347-365.

Yoshihiko Miyata, Hitoshi Nakamoto and Len Neckers


DOI: 10.2174/1381612811306030347




Colchicine Pharmacokinetics and Mechanism of Action

, 2018; 24(6): 659-663.

Christos Angelidis*, Zoi Kotsialou, Charalampos Kossyvakis, Agathi-Rosa Vrettou, Achilleas Zacharoulis, Fotios Kolokathis, Vasilios Kekeris and Georgios Giannopoulos


DOI: 10.2174/1381612824666180123110042


Epidemiology of Non-alcoholic Fatty Liver Disease in North America

, 2020; 26(10): 993-997.

Tamoore Arshad, Pegah Golabi, Linda Henry and Zobair M. Younossi*


DOI: 10.2174/1381612826666200303114934



Executive Editor

Atta-ur-Rahman, FRS
(29381 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
(UK)
Biography

View Full Editorial Board

Nobel Laureate on Editorial Board

Andrew V. Schally
(USA)

Journal History

Current Pharmaceutical Design was introduced in 1995 with the assistance of Dr. William A. Banks.
Scopus CiteScore Metrics: 2.32

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