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Endorsements

"All chemists and scientists will welcome Anti-Cancer Agents in Medicinal Chemistry as a fresh and vital source of information for this important field. The journal is highly recommended for essential reading."

Terrence C. Jenkins
YCR Laboratory of Drug Design, UK

Forthcoming Special Issues

Anti-Cancerous Heterocycles in Focus


Guest Editor(s): Girish Kumar Gupta, Vipin Saini, Prabodh Chander Sharma, Fidele Ntie-Kang
Tentative Publication Date: November, 2018
Submit Abstract via Email Download Description
Special Issues - In-Press
Please visit again after some time to view these Issues.
Published Special Issues

Radiopharmaceuticals for Cancer Therapy and Diagnosis


Anti-Cancer Agents in Medicinal Chemistry, Volume 17, Number 3
Guest Editor(s): Ralph Santos-Oliveira

Authors' Comments
Thank you for the services I got at Bentham Science. It was a great experience publishing my paper entitled" Doxycycline As Potential Anti-cancer Agent" in the Journal "Anti-Cancer Agents In Medicinal Chemistry

Isra Ali
(Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan)


Anti-Cancer Agents in Medicinal Chemistry

,

Volume 18

-

Number 7



Biography   Open Access



Editorial   Open Access



Review Article

Latest Evidence on the Role of Multiparametric Magnetic Resonance Imaging in Active Surveillance for Insignificant Prostate Cancer: A Systematic Review

, 18(7): 925 - 930

Francesco Cantiello*, Stefano Manno, Giorgio I. Russo, Sebastiano Cimino, Salvatore Privitera, Giuseppe Morgia, Antonio Cicione and Rocco Damiano


DOI: 10.2174/1871520618666180105105413




Review Article



Review Article

A Review on the Management of Small Renal Masses: Active Surveillance Versus Surgery

, 18(7): 940 - 950

Giancarlo Marra, Marco Oderda, Marco Allasia, Stefania Munegato, Steven Joniau and Paolo Gontero*


DOI: 10.2174/1871520617666171113123443




Research Article



Research Article

Active Surveillance for Low-risk Prostate Cancer: Are All Criteria Similar?

, 18(7): 958 - 963

Sebastiano Cimino, Salvatore Privitera, Vincenzo Favilla, Francesco Cantiello, Stefano Manno, Antonio Cicione, Rocco Damiano, Giorgio Ivan Russo* and Giuseppe Morgia


DOI: 10.2174/1871520618666180425121617




General Review Article



Anti-Cancer Agents in Medicinal Chemistry, Volume 18 (2018) - Number 10


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 18 (2018) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 18 (2018) - Number 8


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

What Makes Species Productive of Anti-Cancer Drugs? Clues from Drugs’ Species Origin, Druglikeness, Target and Pathway


Xiaofeng Li, Xiaoxu Li, Yinghong Li, Chunyan Yu, Weiwei Xue, Jie Hu*, Bo Li, Panpan Wang and Feng Zhu*


View Abstract View on PubMed



Biological Activity and Physicochemical Properties of Dipeptidyl Nitrile Derivatives Against Pancreatic Ductal Adenocarcinoma Cells


José Carlos Quilles, Murillo Dorileo Leite Bernardi, Pedro Henrique Jatai Batista, Samelyn da Costa Martins Silva, Camila de Melo Romero Rocha, Carlos Alberto Montanari and Andrei Leitão*


View Abstract View on PubMed



Synthesis of Asymmetric 1-Thiocarbamoyl Pyrazoles as Potent Anti- Colon Cancer, Antioxidant and Anti-Inflammatory Agent


Dattatraya G. Raut, Sandeep B. Patil, Vikas D. Kadu, Mahesh G. Hublikar and Raghunath B. Bhosale*


View Abstract View on PubMed


Hydroxyl Group Difference between Anthraquinone Derivatives Regulate Different Cell Death Pathways via Nucleo-Cytoplasmic Shuttling of p53


Mohd Kamil, Ejazul Haque, Snober S. Mir*, Safia Irfan, Adria Hasan, Saba Sheikh, Shamshad Alam, Kausar Mahmood Ansari and Aamir Nazir


View Abstract View on PubMed


Association of Phytol with Toxic and Cytotoxic Activities in an Antitumoral Perspective: A Meta-Analysis and Systemic Review


Mohammed Torequl Islam*, Marcus V.O.B. de Alencar, Eunus S. Ali, Jose V.O. Santos, Marcia F.C.J. Paz, Joao Marcelo de Castro e Sousa, Sandra M.M.M. Dantas, Siddhartha K. Mishra* and Ana Amelia C. Melo-Cavalcante


View Abstract View on PubMed


Evaluation of A Novel GLP-1R Ligand for PET Imaging of Prostate Cancer


Yuanyuan Yue, Yuping Xu, Lirong Huang, Donghui Pan, Zhicheng Bai, Lizhen Wang, Runlin Yang, Junjie Yan, Huizhu Song*, Xiaotian Li and Min Yang


View Abstract View on PubMed



Biochemical and Pharmacological Applications of Essential Oils in Human Health Especially in Cancer Prevention


Siddhartha Kumar Mishra*, Pir Mohammad Ishfaq , Swati Tripathi *, Archana Shukla and Satyaprakash Beraiya


View Abstract View on PubMed


Abstracts Ahead of Print

Let-7a could serve as a biomarker for chemoresistance against docetaxel in gastric cancer.


Tohid Kazemi*, Najibeh Shekari, Faezeh Asghari, Navideh Haghnavaz, Dariush Shanehbandi, Vahid Khaze and Behzad Baradaran


View Abstract


Berberine Effects on NFκB, HIF1A and NFE2L2/AP-1 Pathways in HeLa Cells


Anna Belanova , Darya Beseda , Victor Chmykhalo , Alisa Stepanova , Mariya Belousova , Vera Khrenkova , Nikolaos Gavalas and Peter Zolotukhin*


View Abstract


A Novel Camptothecin Derivative 3j Inhibits Nsclc Proliferation Via Induction of Cell Cycle Arrest By Topo I-Mediated DNA Damage


Yang Liu, Jingyin Zhang, Shuyun Feng, Tingli Zhao, Zhengzheng Li, Lai Wang, Puhai Wang, Hongzhi Du*, Shengtao Yuan* and Li Sun*


View Abstract


Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments.


Evgenii S. Mozhaitsev, Alexandra L. Zakharenko, Evgeniy V. Suslov*, Dina V. Korchagina, Olga D. Zakharova, Inna A. Vasil’eva, Arina A. Chepanova, Ellena Black, Jinal Patel, Raina Chand, Jóhannes Reynisson, Ivanhoe K. H. Leung, Konstantin P. Volcho, Nariman F. Salakhutdinov and Olga I. Lavrik


View Abstract




HOXA4-Dependent Transcriptional Activation of AXL Promotes Cisplatin-Resistance in Lung Adenocarcinoma Cells


Shuo Yu, Hui Ren, Yang Li, Xuan Liang, Qian Ning, Xue Chen, Mingwei Chen and Tinghua Hu*


View Abstract


Isolation of a New Sesquiterpene Lactone From Vernonia Zeylanica (L) Less and its Anti-Proliferative Effects in Breast Cancer Cell Lines.


Anuka S Mendis*, M. Ira Thabrew, Meran K. Ediriweer, Sameera R Samarakoon, Kamani H Tennekoon, Achyut Adhikari* and E. Dilip de Silva


View Abstract


Induction of Apoptosis by pierisin-6 in HPV positive HeLa and HepG2 Cancer Cells is mediated by the caspase-3 dependent mitochondrial pathway.


Subbarayan Sarathbabu, Satheesh Kumar Marimuthu, Souvik Ghatak, Subramanian Vidyalakshmi, Gurusubramanian Guruswami, Sankar Kumar Ghosh, Selvi Subramanian, Wenqing Zhang and Nachimuthu Senthil Kumar*


View Abstract


Synthesis of 3-Arylaminopropenone Linked 2-Arylbenzo[d]imidazo[2,1-b]thiazole Conjugates as Anticancer and Apoptotic Inducing Agents


Ahmed Kamal*, Siddiq Pasha Shaik, T. Srinivasa Reddy, Satish Sunkari, A. V. Subba Rao and Korrapati Suresh Babu


View Abstract


Editor's Choice

Design, Synthesis, and Biological Evaluation of New Azole Derivatives as Potent Aromatase Inhibitors with Potential Effects against Breast Cancer

, 2018; 18(7): 1016 - 1024

Fatemeh Kalalinia, Mohammad Jouya, Alireza K. Komachali, Seyed M. Aboutourabzadeh, Gholamreza Karimi*, Javad Behravan, Khalil Abnous, Leila Etemad, Hossein Kamali and Farzin Hadizadeh*


DOI: 10.2174/1871520618666180116105858





Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents

, 2018; 18(4): 556 - 564

Nikhil R. Madadi, Narsimha R. Penthala, Amit Ketkar, Robert L. Eoff, Vicenta Trujullo-Alonso, Monica L. Guzman and Peter A. Crooks*


DOI: 10.2174/1871521409666170412115703




Novel Findings of Anti-cancer Property of Propofol

, 2018; 18(2): 156 - 165

Jiaqiang Wang, Chien-shan Cheng, Yan Lu, Xiaowei Ding, Minmin Zhu, Changhong Miao* and Jiawei Chen*


DOI: 10.2174/1871520617666170912120327



Evaluation of the in vitro Chemosensitivity and Correlation with Clinical Outcomes in Lung Cancer using the ATP-TCA

, 2018; 18(1): 139 - 145

Zhiyao Chen, Shichao Zhang, Sheng Ma, Chang Li, Chun Xu, Yinfang Shen, Jun Zhao* and Liyan Miao*


DOI: 10.2174/1871520617666170419123713



4-aryl/heteroaryl-4H-fused Pyrans as Anti-proliferative Agents: Design, Synthesis and Biological Evaluation

, 2018; 18(1): 57 - 73

Dinesh Kumar*, Gurpreet Singh, Pooja Sharma, Arem Qayum, Girish Mahajan, M.J. Mintoo, Shashank Kumar Singh, Dilip Manikrao Mondhe, P.M.S. Bedi, Subheet K. Jain and Girish Kumar Gupta


DOI: 10.2174/1871520617666170918143911



Tetrazole Derivatives as Promising Anticancer Agents

, 2017; 17(14): 1856 - 1868

Elena A. Popova*, Aleksandra V. Protas and Rostislav E. Trifonov


DOI: 10.2174/1871520617666170327143148



The Oxime Derivatives of 1-R-1H-Naphtho[2,3-d][1,2,3]triazole-4,9-dione 2-oxides: Synthesis and Properties

, 2017; 17(13): 1814 - 1823

Leonid M. Gornostaev*, Vladimir B. Tsvetkov, Alina A. Markova, Tatyana I. Lavrikova, Yulia G. Khalyavina, Anastasia S. Kuznetsova, Dmitry N. Kaluzhny, Alexei V. Shunayev, Maria V. Tsvetkova, Valeria A. Glazunova, Vladimir V. Chernyshev and Alexander A. Shtil*


DOI: 10.2174/1871520617666170327112216



Open Access Articles

Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*




Tetrazole Derivatives as Promising Anticancer Agents

, 2017; 17(14): 1856 - 1868

Elena A. Popova*, Aleksandra V. Protas and Rostislav E. Trifonov




The Oxime Derivatives of 1-R-1H-Naphtho[2,3-d][1,2,3]triazole-4,9-dione 2-oxides: Synthesis and Properties

, 2017; 17(13): 1814 - 1823

Leonid M. Gornostaev*, Vladimir B. Tsvetkov, Alina A. Markova, Tatyana I. Lavrikova, Yulia G. Khalyavina, Anastasia S. Kuznetsova, Dmitry N. Kaluzhny, Alexei V. Shunayev, Maria V. Tsvetkova, Valeria A. Glazunova, Vladimir V. Chernyshev and Alexander A. Shtil*




Synthesis and Evaluation of Antioxidant and Cytotoxicity of the N-Mannich Base of Berberine Bearing Benzothiazole Moieties

, 2017; 17(12): 1652 - 1660

Bhupendra M. Mistry, Han-Seung Shin, Young-Soo Keum, Muthuraman Pandurangan, Doo Hwan Kim, So Hyun Moon, Avinash A. Kadam, Surendra K. Shinde and Rahul V. Patel*






Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi






Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment

, 2014; 14(8): 1121 - 1127

Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski




Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

, 2014; 14(6): 840 - 851

Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna




β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy

, 2014; 14(3): 343 - 352

Takeo Nomura, Wen-Chin Huang, Haiyen E. Zhau, Sajni Josson, Hiromitsu Mimata and Leland W. K. Chung





Most Cited Articles

Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways

, 2014; 14(1): 77-96.

Andrzej T. Slominski, Michal A. Zmijewski, Igor Semak, Blazej Zbytek, Alexander Pisarchik, Wei Li, Jordan Zjawiony and Robert C. Tuckey


DOI: 10.2174/18715206113139990308




Chemical Metabolic Inhibitors for the Treatment of Blood-Borne Cancers

, 2014; 14(2): 223-232.

Martin Villalba, Nuria Lopez-Royuela, Ewelina Krzywinska, Moeez G. Rathore, Robert A. Hipskind, Houda Haouas and Nerea Allende-Vega


DOI: 10.2174/18715206113136660374


CCL21 and IFNγ Recruit and Activate Tumor Specific T cells in 3D Scaffold Model of Breast Cancer

, 2014; 14(2): 204-210.

Vy Phan-Lai, Forrest M. Kievit, Stephen J. Florczyk, Kui Wang, Mary L. Disis and Miqin Zhang


DOI: 10.2174/18715206113136660375




Most Accessed Articles





Natural Compounds in the Chemoprevention of Malignant Melanoma

, 2018; 18(5): 631-644.

Corina Danciu*, Codruta Soica, Diana Antal, Ersilia Alexa, Ioana Z. Pavel, Roxana Ghiulai, Florina Ardelean, Roxana M. Babuta, Alexandra Popescu and Cristina A. Dehelean


DOI: 10.2174/1871520617666171121142522




BRCA1 as Target for Breast Cancer Prevention and Therapy

, 2015; 15(1): 4-14.

Alberto P.G. Romagnolo, Donato F. Romagnolo and Ornella I. Selmin


DOI: 10.2174/1871520614666141020153543


Natural Macromolecules with Protective and Antitumor Activity

, 2018; 18(5): 675-683.

Cioanca Oana, Trifan Adriana, Cornelia Mircea*, Scripcariu Dragos and Hancianu Monica


DOI: 10.2174/1871520618666180425115029



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