Bentham Science Logo

Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Volume 19, 18 Issues, 2019
ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)
This journal supports open access

Aims & Scope

Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.

Each issue contains a series of timely in-depth/mini reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.

Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.

Anti-Cancer Agents in Medicinal Chemistry

,

Volume 18

-

Number 15



Biography   Open Access



Review Article



Review Article

Cancer Nanotechnology-An Excursion on Drug Delivery Systems

, 18(15): 2078 - 2092

Mala Sharma, Chitranshu Pandey, Neha Sharma, Mohammad A. Kamal, Usman Sayeed and Salman Akhtar*


DOI: 10.2174/1871520618666180720164015


Review Article

The Role of Heat Shock Proteins in Cisplatin Resistance

, 18(15): 2093 - 2109

Zdzisław Krawczyk, Agnieszka Gogler-Pigłowska, Damian R. Sojka and Dorota Scieglinska*


DOI: 10.2174/1871520618666180817114952


Research Article



Research Article



Research Article



Research Article



Anti-Cancer Agents in Medicinal Chemistry, Volume 19 (2019) - Number 2


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 19 (2019) - Number 1


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Synthesis, Biological Investigation and Docking Study of Novel Chromen Derivatives as Anti-Cancer Agents


Pritam N. Dube, Nikhil S. Sakle, Sachin A. Dhawale, Shweta A. More and Santosh N. Mokale*


View Abstract View on PubMed


Synthesis, Characterization, Quantum-Chemical Calculations and Cytotoxic Activity of 1,8-Naphthalimide Derivatives with Non-Protein Amino Acids


Marin Neykov Marinov, Emilia Dimitrova Naydenova*, Georgi Tsvetanov Momekov, Rumyana Yordanova Prodanova, Nadezhda Vasileva Markova, Yulian Tenchev Voynikov and Neyko Marinov Stoyanov


View Abstract View on PubMed


Novel Curcumin Inspired Antineoplastic 1-Sulfonyl-4-Piperidones: Design, Synthesis and Molecular Modeling Studies


Nehmedo G. Fawzy, Siva S. Panda, Walid Fayad, May A. El-Manawaty, Aladdin M. Srour and Adel S. Girgis*


View Abstract View on PubMed




Cancer Therapy Based on Smart Drug Delivery with Advanced Nanoparticles


Xiangqi Kong, Yi Liu, Xueyan Huang, Shuai Huang, Feng Gao, Pengfei Rong, Shengwang Zhang, Kexiang Zhang and Wenbin Zeng*


View Abstract View on PubMed



Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives


Magda F. Mohamed*, Hamdi M. Hassaneen*, Emad M. Elzayat, Salwa M. El-Hallouty, May El-Manawaty, Fatma M. Saleh, Yasmin Mohamed, Dina El-Zohiry, Ghada Fahmy, Nesma Abdelaal, Nouran Hassanin and Nouran Hossam


View Abstract View on PubMed


GPER Overexpression in Cervical Cancer Versus Premalignant Lesions: Its Activation Induces Different forms of Cell Death


Christian David Hernández Silva, Annie Riera-Leal, Pablo César Ortiz-Lazareno, Luis Felipe Jave Suárez, Adrián Ramírez de Arellano, Edgar I. Lopez-Pulido, José G. Macías Barragan, Margarita Montoya Buelna, Judith R. Dávila Rodríguez, Paola Chabay, José Francisco Muñoz-Valle and Ana Laura Pereira-Suárez*


View Abstract View on PubMed


Abstracts Ahead of Print

A cytotoxic natural product from Patrinia villosa Juss


Yangcheng Liu, Wei Liu, Changlan Chen, Zheng Xiang and Hongwei Liu*


View Abstract


Bevacizumab Allows Preservation Of Liver Function and its Regenerative Capacity After Major Hepatectomy


Amparo Valverde, Rubén Ciria, Javier Caballero-Villarras*, Patricia Aguilar-Melero, Gustavo Ferrín, Isidora Ranchal, Clara Linares, Carmen Herencia, Sandra González-Rubio, Manuel de la Mata, Álvaro Naranjo and Javier Briceño


View Abstract



An Inventive Report of Inducing Apoptosis in Non-Small Cell Lung Cancer (NSCLC) Cell Lines by Transfection of MiR-4301


Abbas Jamshidi Avval, Ahmad Majd, Naghmeh Gholipour, Kambiz Akbari Noghabi, Anna Ohradanova-Repic and Ghasem Ahangari*


View Abstract


Prognosis Significance and Positive Correlation of Rab1A and p-S6K/Gli1 Expression in Gastric Cancer


Xinyu Shao, Zhengwu Cheng, Menglin Xu, Jiading Mao, Junfeng Wang* and Chunli Zhou*


View Abstract



Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves


Zouhaier Bouallagui*, Asma Mahmoudi, Amina Maalej, Fatma Hadrich, Hiroko Isoda and Sami Sayadi


View Abstract


LHRH Targeted Chonderosomes of Mitomycin C In Breast Cancer: An In Vitro / In Vivo Study


Jaleh Varshosaz*, Nasim Sarrami, Mahmoud Aghaei, Mehdi Aliomrani and Reza Azizi


View Abstract


The Opposite Effect of L-kynurenine and Ahr Inhibitor Ch223191 on Apoptotic Protein Expression in Pancreatic Carcinoma Cells (Panc-1)


Anna Leja-Szpak*, Marta Góralska, Paweł Link-Lenczowski, Urszula Czech, Katarzyna Nawrot-Porąbka, Joanna Bonior and Jolanta Jaworek


View Abstract



Editor's Choice


Biological Activity and Physicochemical Properties of Dipeptidyl Nitrile Derivatives Against Pancreatic Ductal Adenocarcinoma Cells

, 2019; 19(1): 112 - 120

José C. Quilles, Murillo D.L. Bernardi, Pedro H.J. Batista, Samelyn C.M. Silva, Camila M.R. Rocha, Carlos A. Montanari and Andrei Leitão*


DOI: 10.2174/1871520618666181029141649



Crocetin and Crocin from Saffron in Cancer Chemotherapy and Chemoprevention

, 2019; 19(1): 38 - 47

Alessandro Colapietro, Andrea Mancini, Anna Maria D`Alessandro and Claudio Festuccia*


DOI: 10.2174/1871520619666181231112453



Biomarkers in Non-Small Cell Lung Cancer: Perspectives of Individualized Targeted Therapy

, 2018; 18(15): 2070 - 2077

Mateus N. Aoki*, Marla K. Amarante, Carlos E.C. de Oliveira and Maria A.E. Watanabe


DOI: 10.2174/1871520618666180827102101





Association of Phytol with Toxic and Cytotoxic Activities in an Antitumoral Perspective: A Meta-Analysis and Systemic Review

, 2018; 18(13): 1828 - 1837

Marcus V.O.B. Alencar, Muhammad T. Islam*, Eunus S. Ali, José V.O. Santos, Márcia F.C.J. Paz, João M.C. Sousa, Sandra M.M.M. Dantas, Siddhartha K. Mishra* and Ana A.C.M. Cavalcante


DOI: 10.2174/1871520618666180821113830



One-Pot Synthesis of Triazolo-Heterolignans: Biological Evaluation and Molecular Docking Studies as Tubulin Inhibitors

, 2018; 18(12): 1702 - 1710

Chada Raji Reddy*, Muppidi Subbarao, Jonnalagadda Vijaykumar, Surender Singh Jadav, Nilesh Sasane, Reddi Rani Valleti, Bhukya Supriya and Ramesh Ummanni*


DOI: 10.2174/1871520618666180718104647



Selection of a GPER1 Ligand via Ligand-based Virtual Screening Coupled to Molecular Dynamics Simulations and Its Anti-proliferative Effects on Breast Cancer Cells

, 2018; 18(11): 1629 - 1638

Alberto Martínez-Muñoz, Berenice Prestegui-Martel, David Méndez-Luna, Manuel J. Fragoso-Vázquez*, José Rubén García-Sánchez, Martiniano Bello, Marlet Martínez-Archundia, Alma Chávez-Blanco, Alfonso Dueñas-González, Irene Mendoza-Lujambio, José Trujillo-Ferrara and José Correa-Basurto*


DOI: 10.2174/1871520618666180510121431




Open Access Articles

New Strategies for Therapeutic Cancer Vaccines

, 2019; 19(2): 213 - 221

Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang




Nicotinamide Overcomes Doxorubicin Resistance of Breast Cancer Cells through Deregulating SIRT1/Akt Pathway

, 2019; 19: 1 - 10 (E-Pub Ahead of Print)

Yingze Wei, Yan Guo, Jianyun Zhou, Kui Dai, Qiang Xu and Xiaoxia Jin*




Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*





Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi






Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment

, 2014; 14(8): 1121 - 1127

Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski




Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

, 2014; 14(6): 840 - 851

Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna




β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy

, 2014; 14(3): 343 - 352

Takeo Nomura, Wen-Chin Huang, Haiyen E. Zhau, Sajni Josson, Hiromitsu Mimata and Leland W. K. Chung





Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells

, 2014; 14(1): 170 - 180

Sunil Sagar, Luke Esau, Basem Moosa, Niveen M. Khashab, Vladimir B. Bajic and Mandeep Kaur





Most Cited Articles

Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways

, 2014; 14(1): 77-96.

Andrzej T. Slominski, Michal A. Zmijewski, Igor Semak, Blazej Zbytek, Alexander Pisarchik, Wei Li, Jordan Zjawiony and Robert C. Tuckey


DOI: 10.2174/18715206113139990308




Chemical Metabolic Inhibitors for the Treatment of Blood-Borne Cancers

, 2014; 14(2): 223-232.

Martin Villalba, Nuria Lopez-Royuela, Ewelina Krzywinska, Moeez G. Rathore, Robert A. Hipskind, Houda Haouas and Nerea Allende-Vega


DOI: 10.2174/18715206113136660374


CCL21 and IFNγ Recruit and Activate Tumor Specific T cells in 3D Scaffold Model of Breast Cancer

, 2014; 14(2): 204-210.

Vy Phan-Lai, Forrest M. Kievit, Stephen J. Florczyk, Kui Wang, Mary L. Disis and Miqin Zhang


DOI: 10.2174/18715206113136660375




Most Accessed Articles




Determination of the Apoptotic Effect and Molecular Docking of Benzamide Derivative XT5 in K562 Cells

, 2018; 18(11): 1521-1530.

Tulin Ozkan*, Yalda Hekmatshoar*, Tugba Ertan-Bolelli, Andry N. Hidayat, Meral Beksac, Esin Aki-Yalcin, Ismail Yalcin and Asuman Sunguroglu


DOI: 10.2174/1871520618666171229222534


Potential Pharmacological Inhibitors of Pim Kinase Under Clinical Trials

, 2018; 18(8): 1100-1114.

Gomathi P. Jeyapal, Moola J.N. Chandrasekar*, Rajendiran Krishnasamy, Jubie Selvaraj, Manal Mohammad and Moola J. Nanjan


DOI: 10.2174/1871520618666180131113519


Synthesis and Evaluation of a New Series of Arylidene Indanones as Potential Anticancer Agents

, 2018; 18(10): 1394-1404.

Ahmet Özdemir*, Sevtem Gökbulut, Belgin Sever, Gülşen A. Çiftçi and Mehlika D. Altıntop


DOI: 10.2174/1871520618666171206111923


The Role of Heat Shock Proteins in Cisplatin Resistance

, 2018; 18(15): 2093-2109.

Zdzisław Krawczyk, Agnieszka Gogler-Pigłowska, Damian R. Sojka and Dorota Scieglinska*


DOI: 10.2174/1871520618666180817114952



The Warburg Effect and the Hallmarks of Cancer

, 2017; 17(2): 164-170.

Khalid O. Alfarouk, Claudiu T. Supuran and Laurent Schwartz


DOI: 10.2174/1871520616666161031143301


Sorafenib as a Salvage Therapy in FLT3-ITD Negative Relapse/ Refractory Acute Myeloid Leukemia

, 2018; 18(10): 1489-1494.

Nan Yang, Zhenyang Gu, Zhanxiang Liu, Wenrong Huang, Shuhong Wang, Lili Wang and Chunji Gao*


DOI: 10.2174/1871520618666180307125544




Editor-in-Chief

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
France

Journal History

Current Medicinal Chemistry - Anti-Cancer Agents was launched in 2001 and later renamed in 2006 as Anti-Cancer Agents in Medicinal Chemistry.

Related Journals

Related eBooks

eBooks Catalog