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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Volume 21, 18 Issues, 2021
ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.

Each issue contains a series of timely in-depth/mini reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.

Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.

Anti-Cancer Agents in Medicinal Chemistry

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Volume 21

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Number 5



Biography   Open Access







Review Article

Anticancer Active Heterocyclic Chalcones: Recent Developments

, 21(5): 558 - 566

Prasad Dandawate, Khursheed Ahmed, Subhash Padhye, Aamir Ahmad* and Bernhard Biersack*


DOI: 10.2174/1871520620666200705215722




Review Article

Anti-Cancer Activity of Curcumin on Multiple Myeloma

, 21(5): 575 - 586

Hamed Mirzaei, Hossein Bagheri, Faezeh Ghasemi, Jaber M. Khoi, Mohammad H. Pourhanifeh, Yvan V. Heyden, Erfan Mortezapour, Ali Nikdasti, Philippe Jeandet, Haroon Khan and Amirhossein Sahebkar*


DOI: 10.2174/1871520620666200918113625


Review Article



Research Article

New Spirocyclic Hydroxamic Acids as Effective Antiproliferative Agents

, 21(5): 597 - 610

Margarita E. Neganova, Sergey G. Klochkov, Yulia R. Aleksandrova, Vasily N. Osipov, Dmitry V. Avdeev, Sergey A. Pukhov, Alexandr V. Gromyko and Gjumrakch Aliev*


DOI: 10.2174/1871520620666200527132420


Anti-Cancer Agents in Medicinal Chemistry, Volume 21 (2021) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 21 (2021) - Number 8


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 21 (2021) - Number 7


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 21 (2021) - Number 6


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


1,3,4-Thiadiazolo (3,2-Α) Pyrimidine-6-Carbonitrile Scaffold as PARP1 Inhibitors


Elizabeth Eldhose, Kaviarasan Lakshmanan, Praveen T. Krishnamurthy, Kalirajan Rajagopal, Manal Mohammed, Pulla Prudviraj and Gowramma Byran*


DOI: 10.2174/1871520621666201216095018
View Abstract View on PubMed





Antimutagenic, Antiproliferative and Antioxidant Properties of Sea Grape Leaf Extract Fractions (Coccoloba uvifera L.)


Jorge A. Ramos-Hernández, Montserrat Calderón-Santoyo, Armando Burgos-Hernández, Joel S. García- Romo, Arturo Navarro-Ocaña, María G. Burboa-Zazueta, Edgar Sandoval-Petris and Juan A. Ragazzo- Sánchez*


DOI: 10.2174/1871520621999210104201242
View Abstract View on PubMed



Antineoplastic Activity of an Old Natural Antidiabetic Biguanide on the Human Thyroid Carcinoma Cell Line


Zahra Nozhat, Maryam Zarkesh, Enke Baldini, Samira Mohammadi-Yeganeh*, Feridoun Azizi and Mehdi Hedayati*


DOI: 10.2174/1871520621666210118093532
View Abstract View on PubMed




Abstracts Ahead of Print

Diagnostic and Therapeutic Applications of Exosome Nanovesicles in Lung Cancer: State-of-The-Art


Rezvan Mohammadi, Seyede A. Hosseini, Somaye Noruzi, Ailin Ebrahimzadeh and Amirhossein Sahebkar*


DOI: 10.2174/1871520621666210301085318
View Abstract


Radioprotective Potential of Nutraceuticals and their Underlying Mechanism of Action


Shabnoor Iqbal, Muhammad A. Shah*, Azhar Rasul, Malik Saadullah, Sobia Tabassum, Shujat Ali, Muhammad Zafar, Haji Muhammad, Md Sahab Uddin, Gaber El-Saber Batiha and Celia Vargas-De-La-Cruz


DOI: 10.2174/1871520621666210223101246
View Abstract


Xanthohumol: A Metabolite with Promising Anti-Neoplastic Potential


Hardeep S. Tuli*, Vaishali Aggarwal, Gaurav Parashar, Diwakar Aggarwal, Nidarshana C. Parashar, Muobarak J. Tuorkey, Mehmet Varol, Katrin Sak, Manoj Kumar and Harpal S. Buttar


DOI: 10.2174/1871520621666210223095021
View Abstract




Anti-Tumor Efficacy of Pyrvinium Pamoate Nanoliposomes in an Experimental Model of Melanoma.


Mahdi Hatamipour, Mahmoud R. Jaafari, Mahtab Zangui, Neda Shakour and Amirhossein Sahebkar*


DOI: 10.2174/1871520621666210217095627
View Abstract


Emerging molecular functions of microRNA-9: Cancer pathology and therapeutic implications


Behnam E.G. Tapeh , Bashir Mosayyebi, Behzad Mansoori , Zahra A. Gravand, Hamzeh Sarvnaz and Ali Mohammadi *


DOI: 10.2174/1871520621666210217094839
View Abstract



Antiproliferative Activity of Cissus quadrangularis L. Extract against Human Cervical Cancer Cells: In Vitro and In Silico Analysis


Sahabjada Siddiqui*, Qamar Zia, Mohd Abbas, Sushma Verma, Asif Jafri, Deepika Misra, Suaib Luqman, Maqusood Ahamed, Mohd Sultan Ahmad and Md Arshad


DOI: 10.2174/1871520621666210210103729
View Abstract



Published Contents

Editor's Choice

Anticancer Active Heterocyclic Chalcones: Recent Developments

, 2021; 21(5): 558 - 566

Prasad Dandawate, Khursheed Ahmed, Subhash Padhye, Aamir Ahmad* and Bernhard Biersack*


DOI: 10.2174/1871520620666200705215722



Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid

, 2021; 21(4): 462 - 467

Agnieszka Siebert, Milena Deptuła, Mirosława Cichorek, Anna Ronowska, Grzegorz Cholewiński* and Janusz Rachon


DOI: 10.2174/1871520620666200516151456



Benzimidazole Derivative Ameliorates Opioid-Mediated Tolerance during Anticancer- Induced Neuropathic Pain in Mice

, 2021; 21(3): 365 - 371

Sana Akhtar, Muzaffar Abbas*, Komal Naeem, Muhammad Faheem, Humaira Nadeem and Amber Mehmood


DOI: 10.2174/1871520620999200818155031




Therapy Resistance in Cancers: Phenotypic, Metabolic, Epigenetic and Tumour Microenvironmental Perspectives

, 2020; 20(18): 2190 - 2206

Tasnim Zahan, Plabon K. Das, Syeda F. Akter, Rowshanul Habib, Md. Habibur Rahman, Md. Rezaul Karim* and Farhadul Islam*


DOI: 10.2174/1871520620999200730161829








Open Access Articles


The Killing of Human Neuroblastoma Cells by the Small Molecule JQ1 Occurs in a p53-Dependent Manner

, 2020; 20(13): 1613 - 1625

Joseph Mazar*, Caleb Gordon, Varun Naga and Tamarah J. Westmoreland




Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells

, 2020; 20(6): 687 - 699

Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang





Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis

, 2019; 19(10): 1253 - 1261

Naipeng Cui, Dan-Dan Lin, Yang Shen, Jian-Guo Shi, Bing Wang, Ming-Zhi Zhao, Lishuang Zheng, Hua Chen* and Jian-Hong Shi*





New Strategies for Therapeutic Cancer Vaccines

, 2019; 19(2): 213 - 221

Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang




Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*





Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi







Most Cited Articles



Research Article

Beta-caryophyllene suppresses ovarian cancer proliferation by inducing cell cycle arrest and apoptosis

, 2020; 20(13): 1530-1537.

Santhosh Arul, Harinee Rajagopalan, Jivitesh Ravi and Haripriya Dayalan*


DOI: 10.2174/1871520620666200227093216


Review Article

Cdk1 in breast cancer: Implications for theranostic potential

, 2020; 20(7): 758-767.

Sepideh Izadi, Afshin Nikkhoo, Mohammad Hojjat-Farsangi, Afshin Namdar, Gholamreza Azizi, Hamed Mohammadi, Mehdi Yousefi and Farhad Jadidi-Niaragh*


DOI: 10.2174/1871520620666200203125712


Research Article

Molecular docking study, cytotoxicity, cell cycle arrest and apoptotic induction of novel chalcones incorporating thiadiazolyl isoquinoline in cervical cancer

, 2020; 20(1): 70-83.

Mohamed A. Tantawy, Farid M. Sroor*, Magda F. Mohamed*, Mostafa E. El-Naggar, Fatma M. Saleh, Hamdi M. Hassaneen and Ismail A. Abdelhamid*


DOI: 10.2174/1871520619666191024121116


Review Article

Nanoformulations of coumarins and the hybrid molecules of coumarins with potential anticancer effects

, 2020; 20(15): 1797-1816.

Mukerrem Betul Yerer*, Serkan Dayan, M. Ihsan Han, Ajay Sharma, Hardeep S. Tuli and Katrin Sak


DOI: 10.2174/1871520620666200310094646


Review Article

Recent advances of silver nanoparticles in cancer diagnosis and treatment

, 2020; 20(11): 1276-1287.

Tran Q. Huy*, Pham T.M. Huyen, Anh-Tuan Le and Matteo Tonezzer*


DOI: 10.2174/1871520619666190710121727


Research Article

Ruxolitinib regulates the autophagy machinery in multiple myeloma cells

, 2020; 20(18): 2316-2323.

Alican Kusoglu*, Bakiye G. Bagca, Neslihan P.O. Ay, Guray Saydam and Cigir B. Avci


DOI: 10.2174/1871520620666200218105159



Research Article

Anti-metastatic effects of lupeol via the inhibition of MAPK/ERK pathway in lung cancer

, 2021; 21(2): 201-206.

Mital Bhatt, Mitesh Patel*, Mohd Adnan and Mandadi N. Reddy


DOI: 10.2174/1871520620666200424131548


Review Article

Aromatase inhibitors for the treatment of breast cancer: A journey from the scratch

, 2020; 20(17): 1994-2004.

Pooja Ratre, Keerti Mishra, Amit Dubey, Amber Vyas, Akhlesh Jain* and Suresh Thareja*


DOI: 10.2174/1871520620666200627204105




Research Article

Molecular docking, antioxidant, anticancer and antileishmanial effects of newly synthesized quinoline derivatives

, 2020; 20(13): 1516-1529.

Zoonish Malghani, Arif-Ullah Khan*, Muhammad Faheem, Muhammad Z. Danish, Humaira Nadeem, Sameen F. Ansari and Madeeha Maqbool


DOI: 10.2174/1871520620666200516145117




Most Accessed Articles



On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids against Breast Tumor Cells (MDA-231 and MCF-7)

, 2021; 21(9): 1172-1182.

Celisnolia M. Leite*, João Honorato de Araujo-Neto, Rodrigo S. Corrêa, Legna Colina-Vegas, Diego Martínez-Otero, Paulo R. Martins, Cristiane G. Silva and Alzir A. Batista*


DOI: 10.2174/1871520620666200824114816



A New Series of Antileukemic Agents: Design, Synthesis, In Vitro and In Silico Evaluation of Thiazole-Based ABL1 Kinase Inhibitors

, 2021; 21(9): 1099-1109.

Ebru Zeytün, Mehlika D. Altıntop*, Belgin Sever, Ahmet Özdemir, Doha E. Ellakwa, Zeynep Ocak, Halil I. Ciftci, Masami Otsuka, Mikako Fujita* and Mohamed O. Radwan*


DOI: 10.2174/1871520620666200824100408



The Engaged Role of Tumor Microenvironment in Cancer Metabolism: Focusing on Cancer-Associated Fibroblast and Exosome Mediators

, 2021; 21(2): 254-266.

Khandan Ilkhani, Milad Bastami, Soheila Delgir, Asma Safi, Shahrzad Talebian and Mohammad-Reza Alivand*


DOI: 10.2174/1871520620666200910123428





A Review of Chemotherapy and Photodynamic Therapy for Lung Cancer Treatment

, 2021; 21(2): 149-161.

Ahmed El-Hussein*, Sello L. Manoto, Saturnin Ombinda-Lemboumba, Ziya A. Alrowaili and Patience Mthunzi-Kufa


DOI: 10.2174/1871520620666200403144945


New Hybrid Scaffolds Based on Carbazole-Chalcones as Potent Anticancer Agents

, 2021; 21(9): 1082-1091.

Faisal Rashid, Sumera Zaib, Aliya Ibrar*, Syeda A. Ejaz, Aamer Saeed, Imtiaz Khan* and Jamshed Iqbal*


DOI: 10.2174/1871520620666200721110732


Synthesis and in vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents

, 2021; 21(9): 1127-1140.

Upasana Yadav, Yogesh Vanjari, Kritika Laxmikeshav, Ramya Tokala, Praveen K. Niggula, Manoj Kumar, Venu Talla*, Ahmed Kamal and Nagula Shankaraiah*


DOI: 10.2174/1871520620666200714142931


Antibody-Based Targeted Interventions for the Diagnosis and Treatment of Skin Cancers

, 2021; 21(2): 162-186.

Suresh Madheswaran, Neelakshi Mungra, Fleury A.N. Biteghe, Jean De la Croix Ndong, Afolake T. Arowolo, Henry A. Adeola, Dharanidharan Ramamurthy, Krupa Naran, Nonhlanhla P. Khumalo and Stefan Barth*


DOI: 10.2174/1871520620666200728123006


New Formulation and Evaluation of Camptothecin Encapsulated and/or Dispersed Suppository

, 2021; 21(9): 1183-1190.

Sofiane Fatmi*, Lamia Taouzinet, Malika Lahiani-Skiba, Mohamed Skiba and Mokrane Iguer-Ouada


DOI: 10.2174/1871520620666200903150635



Editor-in-Chief

graphic
Simone Carradori
Department of Pharmacy
“G. d’Annunzio” University of Chieti-Pescara
Chieti
(Italy)
Biography
View Full Editorial Board

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Journal History

Current Medicinal Chemistry - Anti-Cancer Agents was launched in 2001 and later renamed in 2006 as Anti-Cancer Agents in Medicinal Chemistry.

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