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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Volume 20, 18 Issues, 2020
ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.

Each issue contains a series of timely in-depth/mini reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.

Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.

Anti-Cancer Agents in Medicinal Chemistry

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Volume 20

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Number 8



Biography   Open Access



Review Article

Anti-Tumor Effects of Osthole on Different Malignant Tissues: A Review of Molecular Mechanisms

, 20(8): 918 - 931

Milad Ashrafizadeh, Reza Mohammadinejad, Saeed Samarghandian, Habib Yaribeygi*, Thomas P. Johnston and Amirhossein Sahebkar*


DOI: 10.2174/1871520620666200228110704


Research Article



Research Article



Research Article

In Vitro Inhibitory Effect of Recombinant Human Calprotectin on Nalm6 Leukemia Cell Line

, 20(8): 951 - 962

Samira Charkhizadeh, Mehdi Imani, Nematollah Gheibi, Fateme Shabaani, Akbar Nikpajouh and Mohammad R. Rezvany*


DOI: 10.2174/1871520620666200331101209


Research Article



Research Article



Research Article



Anti-Cancer Agents in Medicinal Chemistry, Volume 20 (2020) - Number 13


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 20 (2020) - Number 12


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 20 (2020) - Number 11


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 20 (2020) - Number 10


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 20 (2020) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print




Anticancer Activity Assessment and DNA Binding Properties of Two Binuclear Platinum (II) Complexes using Spectroscopic and Molecular Simulation Approaches


M. Mehdi Alavianmehr, Abolfazal Ashrafi*, Reza Yousefi, Mohsen G. Haghighi, Samira S. Abolmaali, Mohammad N.S. Rad and Ali A. Moosavi-Movahedi


DOI: 10.2174/1871520620666200705221325
View Abstract View on PubMed


Natural Products: Implication in Cancer Prevention and Treatment through Modulating Various Biological Activities


Shehwaz Anwar, Ahmad Almatroudi, Mohammed A. Alsahli, Masood A. Khan, Amjad A. Khan and Arshad H. Rahmani*


DOI: 10.2174/1871520620666200705220307
View Abstract View on PubMed




HCA587 protein vaccine induces specific antitumor immunity mediated by CD4+ T-cells expressing granzyme B in a mouse model of melanoma


Weiming Yang, Weiheng Zhang, Xiaozhong Wang, Liming Tan, Hua Li, Jiemin Wu, Qiong Wu, Wanlei Sun, Juanjuan Chen* and Yanhui Yin


DOI: 10.2174/1871520620666200728131951
View Abstract



Apoptotic Effects of N-(2-hydroxyphenyl)-2-propylpentanamide on U87-MG and U-2 OS Cells and Antiangiogenic Properties


Paola Castillo-Juárez, Sebastián C. Sanchez, Alma D. Chávez-Blanco*, Humberto Mendoza-Figueroa and José Correa-Basurto


DOI: 10.2174/1871520620666200728125356
View Abstract


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice





Insights into Nano-Photo-Thermal Therapy of Cancer: The Kinetics of Cell Death and Effect on Cell Cycle

, 2020; 20(5): 612 - 621

Mousa Tabei, Elham Zeinizade, Jaber Beik, S. Kamran Kamrava, Zahra Nasiri, Habib Ghaznavi* and Ali Shakeri-Zadeh*


DOI: 10.2174/1871520620666200129111332



The Antitumor Activity of a Novel Fluorobenzamidine against Dimethylhydrazine- Induced Colorectal Cancer in Rats

, 2020; 20(4): 450 - 463

Mohammed Abdel-Rasol, Nadia M. El-Beih, Shaymaa M.M. Yahya, Mohamed A. Ismail and Wael M. El-Sayed*


DOI: 10.2174/1871520619666191021162411



New Uracil Analogs with Exocyclic Methylidene Group as Potential Anticancer Agents

, 2020; 20(3): 359 - 368

Angelika Długosz-Pokorska, Joanna Drogosz, Marlena Pięta, Tomasz Janecki, Urszula Krajewska, Marek Mirowski and Anna Janecka*


DOI: 10.2174/1871520619666191211104128



Radio-thermo-sensitivity Induced by Gold Magnetic Nanoparticles in the Monolayer Culture of Human Prostate Carcinoma Cell Line DU145

, 2020; 20(3): 315 - 324

Zhila Rajaee, Samideh Khoei*, Alireza Mahdavian, Sakine Shirvalilou*, Seied R. Mahdavi and Marzieh Ebrahimi


DOI: 10.2174/1871520620666191216113052



Anticancer Potential of Dietary Natural Products: A Comprehensive Review

, 2020; 20(2): 122 - 236

Rumana Ahmad*, Mohsin A. Khan, A.N. Srivastava, Anamika Gupta, Aditi Srivastava, Tanvir R. Jafri, Zainab Siddiqui, Sunaina Chaubey, Tahmeena Khan and Arvind K. Srivastava


DOI: 10.2174/1871520619666191015103712



Oxidative Stress Modulation and Radiosensitizing Effect of Quinoxaline-1,4-Dioxides Derivatives

, 2020; 20(1): 111 - 120

Liliana Silva, Pedro Coelho, Dulce Teixeira, Armanda Monteiro, Gabriela Pinto, Raquel Soares, Cristina Prudêncio and Mónica Vieira*


DOI: 10.2174/1871520619666191028091547



Open Access Articles

The Killing of Human Neuroblastoma Cells by the Small Molecule JQ1 Occurs in a p53-Dependent Manner

, 2020; 20(13): 1613 - 1625

Joseph Mazar*, Caleb Gordon, Varun Naga and Tamarah J. Westmoreland




Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells

, 2020; 20(6): 687 - 699

Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang





Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis

, 2019; 19(10): 1253 - 1261

Naipeng Cui, Dan-Dan Lin, Yang Shen, Jian-Guo Shi, Bing Wang, Ming-Zhi Zhao, Lishuang Zheng, Hua Chen* and Jian-Hong Shi*





New Strategies for Therapeutic Cancer Vaccines

, 2019; 19(2): 213 - 221

Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang




Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*





Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi






Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment

, 2014; 14(8): 1121 - 1127

Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski





Most Cited Articles


Research Article

Let-7a could serve as a biomarker for chemo-responsiveness to docetaxel in gastric cancer

, 2019; 19(3): 304-309.

Najibeh Shekari, Faezeh Asghari, Navideh Haghnavaz, Dariush Shanehbandi, Vahid Khaze, Behzad Baradaran and Tohid Kazemi*


DOI: 10.2174/1871520619666181213110258


Review Article

Phytochemicals in anticancer drug development

, 2019; 19(2): 172-183.

Rohit Dutt, Vandana Garg, Naveen Khatri and Anil K. Madan*


DOI: 10.2174/1871520618666181106115802


Review Article

Crocetin and crocin from saffron in cancer chemotherapy and chemoprevention

, 2019; 19(1): 38-47.

Alessandro Colapietro, Andrea Mancini, Anna Maria D'Alessandro and Claudio Festuccia*


DOI: 10.2174/1871520619666181231112453


Research Article

What makes species productive of anti-cancer drugs? Clues from drugs’ species origin, druglikeness, target and pathway

, 2019; 19(2): 194-203.

Xiaofeng Li, Xiaoxu Li, Yinghong Li, Chunyan Yu, Weiwei Xue, Jie Hu*, Bo Li, Panpan Wang and Feng Zhu*


DOI: 10.2174/1871520618666181029132017


Review Article

Immunotherapy in patients with recurrent and metastatic squamous cell carcinoma of the head and neck

, 2019; 19(3): 290-303.

Izabela Łasińska*, Tomasz Kolenda, Anna Teresiak, Katarzyna M. Lamperska, Łukasz Galus and Jacek Mackiewicz


DOI: 10.2174/1871520618666180910092356


Research Article

Novel inhibitors of DNA repair enzyme TDP1 combining monoterpenoid and adamantane fragments

, 2019; 19(4): 463-472.

Evgenii S. Mozhaitsev, Alexandra L. Zakharenko, Evgeniy V. Suslov*, Dina V. Korchagina, Olga D. Zakharova, Inna A. Vasil'eva, Arina A. Chepanova, Ellena Black, Jinal Patel, Raina Chand, Jóhannes Reynisson, Ivanhoe K.H. Leung, Konstantin P. Volcho, Nariman F. Salakhutdinov and Olga I. Lavrik


DOI: 10.2174/1871520619666181207094243



Research Article

Hydroxytyrosol and oleuropein inhibit migration and invasion of MDA-MB-231 triple-negative breast cancer cell via induction of autophagy

, 2019; 19(16): 1983-1990.

Hui-Yuan Lu*, Jian-Sheng Zhu, Zhan Zhang, Wei-Jian Shen, Shan Jiang, Yun-Feng Long, Bin Wu, Tao Ding, Fei Huan and Shou-Lin Wang


DOI: 10.2174/1871520619666190722101207


Research Article

[10]-gingerol affects multiple metastatic processes and induces apoptosis in MDA-MB-231 breast tumor cells

, 2019; 19(5): 645-654.

Angelina M. Fuzer, Ana C.B.M. Martin, Amanda B. Becceneri, James A. da Silva, Paulo C. Vieira and Marcia R. Cominetti*


DOI: 10.2174/1871520618666181029125607


Research Article

Synthesis and biological evaluation of novel heterocyclic imines linked coumarin- thiazole hybrids as anticancer agents

, 2019; 19(4): 557-566.

Nerella S. Goud, Mahammad S. Ghouse, Jatoth Vishnu, Jakkula Pranay, Ravi Alvala, Venu Talla, Insaf A. Qureshi and Mallika Alvala*


DOI: 10.2174/1871520619666190207140120



Research Article

Novel curcumin inspired antineoplastic 1-sulfonyl-4-piperidones: Design, synthesis and molecular modeling studies

, 2019; 19(8): 1069-1078.

Nehmedo G. Fawzy, Siva S. Panda, Walid Fayad, May A. El-Manawaty, Aladdin M. Srour and Adel S. Girgis*


DOI: 10.2174/1871520619666190408131639


Review Article

Integrins as a new target for cancer treatment

, 2019; 19(5): 580-586.

Izabela Łasiñska* and Jacek Mackiewicz


DOI: 10.2174/1871520618666181119103413


Research Article

3, 3'-Dimethylquercetin inhibits the proliferation of human colon cancer RKO cells through inducing G2/M cell cycle arrest and apoptosis

, 2019; 19(3): 402-409.

Jianguo Wu, Jun Yi, Yanbin Wu, Xuzheng Chen, Jianwei Zeng, Jinzhong Wu* and Wei Peng*


DOI: 10.2174/1871520618666181106120718



Most Accessed Articles


The Warburg Effect and the Hallmarks of Cancer

, 2017; 17(2): 164-170.

Khalid O. Alfarouk, Claudiu T. Supuran and Laurent Schwartz


DOI: 10.2174/1871520616666161031143301


Inhibitors of Cancer Stem Cells

, 2016; 16(10): 1230-1239.

María E. García-Rubiño, César Lozano-López and Joaquín M. Campos


DOI: 10.2174/1871520616666160330104715



Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer

, 2020; 20(1): 70-83.

Mohamed A. Tantawy, Farid M. Sroor*, Magda F. Mohamed*, Mostafa E. El-Naggar, Fatma M. Saleh, Hamdi M. Hassaneen and Ismail A. Abdelhamid*


DOI: 10.2174/1871520619666191024121116



Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells

, 2020; 20(6): 687-699.

Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang


DOI: 10.2174/1871520620666200213102849


Anticancer Potential of Dietary Natural Products: A Comprehensive Review

, 2020; 20(2): 122-236.

Rumana Ahmad*, Mohsin A. Khan, A.N. Srivastava, Anamika Gupta, Aditi Srivastava, Tanvir R. Jafri, Zainab Siddiqui, Sunaina Chaubey, Tahmeena Khan and Arvind K. Srivastava


DOI: 10.2174/1871520619666191015103712


Recent Advances in Characterizing Natural Products that Regulate Autophagy

, 2019; 19(18): 2177-2196.

Qian Zhao, Cheng Peng, Chuan Zheng, Xiang-Hong He, Wei Huang* and Bo Han*


DOI: 10.2174/1871520619666191015104458




Editor-in-Chief

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
(France)
Biography
View Full Editorial Board

Journal History

Current Medicinal Chemistry - Anti-Cancer Agents was launched in 2001 and later renamed in 2006 as Anti-Cancer Agents in Medicinal Chemistry.

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