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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Volume 20, 18 Issues, 2020
ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)
This journal supports open access

Ranking and Category

  • 39th of 61 in

    Chemistry, Medicinal

  • 172nd of 229 in

    Oncology

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Aims & Scope

Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.

Each issue contains a series of timely in-depth/mini reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.

Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.

Anti-Cancer Agents in Medicinal Chemistry

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Volume 19

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Number 18



Biography   Open Access



Review Article



Review Article



Research Article



Research Article



Research Article



Research Article

Effect of Hsp90 Inhibitor KW-2478 on HepG2 Cells

, 19(18): 2231 - 2242

Xiaomin Chang, Xuerong Zhao, Jianping Wang, Shi Ding, Lijun Xiao*, Enhong Zhao and Xin Zheng


DOI: 10.2174/1871520619666191023094610


Research Article



Anti-Cancer Agents in Medicinal Chemistry, Volume 20 (2020) - Number 1


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print






The effect of Phase Transition Temperature on Therapeutic Efficacy of Liposomal Bortezomib


Mitra Korani, Sara Nikoofal-Sahlabadi, Amin R. Nikpoor, Solmaz Ghaffari, Hossein Attar, Mohammad Mashreghi and Mahmoud R. Jaafari*


DOI: 10.2174/1871520620666200101150640
View Abstract View on PubMed


Synthesis, Biological Evaluation and Molecular Docking Study of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics


Yang Lu, Hyunji Jo, Md Arifuzzaman, Hwa-Jong Lee, Wencui Yin, Mohammad S. Alam, Moinul Karim, Adnan A. Kadi, Yurngdong Jahng, Youngjoo Kwon and A.F.M. Motiur Rahman*


DOI: 10.2174/1871520619666191125130237
View Abstract View on PubMed





Abstracts Ahead of Print

Synthesis of Dihydrazones as Potential Anticancer and DNA Binding Candidates: A Validation by Molecular Docking Studies


Malavalli B. Sridhara, Kodagahalli P. Rakesh, Honnayakanahalli M. Manukumar, Chavalmane S. Shantharam, H.K. Vivek, H.K. Kumara, Yasser H.E. Mohammed and D. Channe Gowda*


DOI: 10.2174/1871520620666200225104558
View Abstract






CDK1 in Breast Cancer: Implications for Theranostic Potential


Sepideh Izadi, Afshin Nikkhoo, Mohammad Hojjat-Farsangi, Afshin Namdar, Gholamreza Azizi, Hamed Mohammadi, Mehdi Yousefi and Farhad Jadidi-Niaragh*


DOI: 10.2174/1871520620666200203125712
View Abstract



Metalloproteinases Suppression Driven by the Curcumin Analog DM-1 Modulates Invasion in BRAF-Resistant Melanomas


Nayane de Souza*, Érica Aparecida de Oliveira*, Fernanda Faião-Flores, Luciana A. Pimenta, José A.P. Quincoces, Sandra C. Sampaio and Silvya S. Maria-Engler


DOI: 10.2174/1871520620666200218111422
View Abstract



Ruxolitinib Regulates the Autophagy Machinery in Multiple Myeloma Cells


Alican Kusoglu*, Bakiye G. Bagca*, Neslihan P. Ozates Ay, Guray Saydam and Cigir B. Avci


DOI: 10.2174/1871520620666200218105159
View Abstract


Published Contents

Editor's Choice



Zoning in on Tankyrases: A Brief Review on the Past, Present and Prospective Studies

, 2019; 19(16): 1920 - 1934

Xylia Q. Peters, Thembeka H. Malinga, Clement Agoni, Fisayo A. Olotu and Mahmoud E.S. Soliman*


DOI: 10.2174/1871520619666191019114321








Synthesis, Spectroscopic Properties, Crystal Structure And Biological Evaluation of New Platinum Complexes with 5-methyl-5-(2-thiomethyl)ethyl Hydantoin

, 2019; 19(10): 1243 - 1252

Adriana G. Bakalova*, Rossen T. Buyukliev, Rositsa P. Nikolova, Boris L. Shivachev, Rositsa A. Mihaylova and Spiro M. Konstantinov


DOI: 10.2174/1871520619666190214103345




Open Access Articles


Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis

, 2019; 19(10): 1253 - 1261

Naipeng Cui, Dan-Dan Lin, Yang Shen, Jian-Guo Shi, Bing Wang, Ming-Zhi Zhao, Lishuang Zheng, Hua Chen* and Jian-Hong Shi*





New Strategies for Therapeutic Cancer Vaccines

, 2019; 19(2): 213 - 221

Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang




Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*





Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi






Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment

, 2014; 14(8): 1121 - 1127

Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski




Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

, 2014; 14(6): 840 - 851

Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna




β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy

, 2014; 14(3): 343 - 352

Takeo Nomura, Wen-Chin Huang, Haiyen E. Zhau, Sajni Josson, Hiromitsu Mimata and Leland W. K. Chung





Most Cited Articles

Research Article

Let-7a could serve as a biomarker for chemo-responsiveness to docetaxel in gastric cancer

, 2019; 19(3): 304-309.

Najibeh Shekari, Faezeh Asghari, Navideh Haghnavaz, Dariush Shanehbandi, Vahid Khaze, Behzad Baradaran and Tohid Kazemi*


DOI: 10.2174/1871520619666181213110258


Research Article

Novel inhibitors of DNA repair enzyme TDP1 combining monoterpenoid and adamantane fragments

, 2019; 19(4): 463-472.

Evgenii S. Mozhaitsev, Alexandra L. Zakharenko, Evgeniy V. Suslov*, Dina V. Korchagina, Olga D. Zakharova, Inna A. Vasil'eva, Arina A. Chepanova, Ellena Black, Jinal Patel, Raina Chand, Jóhannes Reynisson, Ivanhoe K.H. Leung, Konstantin P. Volcho, Nariman F. Salakhutdinov and Olga I. Lavrik


DOI: 10.2174/1871520619666181207094243



Research Article

What makes species productive of anti-cancer drugs? Clues from drugs’ species origin, druglikeness, target and pathway

, 2019; 19(2): 194-203.

Xiaofeng Li, Xiaoxu Li, Yinghong Li, Chunyan Yu, Weiwei Xue, Jie Hu*, Bo Li, Panpan Wang and Feng Zhu*


DOI: 10.2174/1871520618666181029132017


Review Article

Phytochemicals in anticancer drug development

, 2019; 19(2): 172-183.

Rohit Dutt, Vandana Garg, Naveen Khatri and Anil K. Madan*


DOI: 10.2174/1871520618666181106115802


Research Article

3, 3'-Dimethylquercetin inhibits the proliferation of human colon cancer RKO cells through inducing G2/M cell cycle arrest and apoptosis

, 2019; 19(3): 402-409.

Jianguo Wu, Jun Yi, Yanbin Wu, Xuzheng Chen, Jianwei Zeng, Jinzhong Wu* and Wei Peng*


DOI: 10.2174/1871520618666181106120718



Review Article

Immunotherapy in patients with recurrent and metastatic squamous cell carcinoma of the head and neck

, 2019; 19(3): 290-303.

Izabela Łasińska*, Tomasz Kolenda, Anna Teresiak, Katarzyna M. Lamperska, Łukasz Galus and Jacek Mackiewicz


DOI: 10.2174/1871520618666180910092356


Research Article

[10]-gingerol affects multiple metastatic processes and induces apoptosis in MDA-MB-231 breast tumor cells

, 2019; 19(5): 645-654.

Angelina M. Fuzer, Ana C.B.M. Martin, Amanda B. Becceneri, James A. da Silva, Paulo C. Vieira and Marcia R. Cominetti*


DOI: 10.2174/1871520618666181029125607



Research Article

Induction of apoptosis by pierisin-6 in HPV Positive HeLa and HepG2 cancer cells is mediated by the caspase-3 dependent mitochondrial pathway

, 2019; 19(3): 337-346.

Subbarayan Sarathbabu, Satheesh K. Marimuthu, Souvik Ghatak, Subramanian Vidyalakshmi, Guruswami Gurusubramanian, Sankar K. Ghosh, Selvi Subramanian*, Wenqing Zhang and Nachimuthu S. Kumar*


DOI: 10.2174/1871520619666181127113848



Review Article

Crocetin and crocin from saffron in cancer chemotherapy and chemoprevention

, 2019; 19(1): 38-47.

Alessandro Colapietro, Andrea Mancini, Anna Maria D'Alessandro and Claudio Festuccia*


DOI: 10.2174/1871520619666181231112453


General Research Article

Biological activity and physicochemical properties of dipeptidyl nitrile derivatives against pancreatic ductal adenocarcinoma cells

, 2019; 19(1): 112-120.

José C. Quilles Jr, Murillo D.L. Bernardi, Pedro H.J. Batista, Samelyn C.M. Silva, Camila M.R. Rocha, Carlos A. Montanari and Andrei Leitão*


DOI: 10.2174/1871520618666181029141649


Research Article

Hydroxytyrosol and oleuropein inhibit migration and invasion of MDA-MB-231 triple-negative breast cancer cell via induction of autophagy

, 2019; 19(16): 1983-1990.

Hui-Yuan Lu*, Jian-Sheng Zhu, Zhan Zhang, Wei-Jian Shen, Shan Jiang, Yun-Feng Long, Bin Wu, Tao Ding, Fei Huan and Shou-Lin Wang


DOI: 10.2174/1871520619666190722101207



Most Accessed Articles


Nitrogen Mustards as Alkylating Agents: A Review on Chemistry, Mechanism of Action and Current USFDA Status of Drugs

, 2019; 19(9): 1080-1102.

Ghansham S. More*, Asha B. Thomas, Sohan S. Chitlange, Rabindra K. Nanda and Rahul L. Gajbhiye


DOI: 10.2174/1871520619666190305141458



The Warburg Effect and the Hallmarks of Cancer

, 2017; 17(2): 164-170.

Khalid O. Alfarouk, Claudiu T. Supuran and Laurent Schwartz


DOI: 10.2174/1871520616666161031143301


Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis

, 2019; 19(10): 1253-1261.

Naipeng Cui, Dan-Dan Lin, Yang Shen, Jian-Guo Shi, Bing Wang, Ming-Zhi Zhao, Lishuang Zheng, Hua Chen* and Jian-Hong Shi*


DOI: 10.2174/1871520619666190404155230









Editor-in-Chief

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
France

Biography View Full Editorial Board

Journal History

Current Medicinal Chemistry - Anti-Cancer Agents was launched in 2001 and later renamed in 2006 as Anti-Cancer Agents in Medicinal Chemistry.

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