Anti-Cancer Agents in Medicinal Chemistry

Authors are requested to electronically submit their papers to this journal for evaluation and submission at https://bentham.manuscriptpoint.com/journals/acamc/ View Submission Instructions. The Manuscript Processing System (MPS) has been designed to ensure step-by-step online processing and tracking of manuscripts for authors, editors and the publisher from submission to acceptance and final reproduction.

Through the submission process, this website will guide authors through each stage of the submission process. The text, tables, and artwork should be uploaded at (https://bentham.manuscriptpoint.com/journals/acamc) in electronic format by the authors. However, the authors who are unable to provide an electronic version or who are facing other difficulties must contact the editorial office by emailing at [email protected] to discuss any alternatives. Submissions that do not adhere to these guidelines will unfortunately not be taken into consideration.

Manuscripts must be submitted by one of the authors of the manuscript, and should not be submitted by anyone on their behalf. The principal/corresponding author will be required to submit a Copyright Letter along with the manuscript, on behalf of all the co-authors (if any). The author(s) will confirm that the manuscript (or any part of it) has not been published previously or is not under consideration for publication elsewhere. Furthermore, any illustration, structure, or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained.

The author's time is valuable and should not be wasted on research formatting. Free Format Submission makes it easier and faster to prepare text for submission.

When submitting to any Bentham journal, authors are not required to follow any formatting guidelines. When an article is accepted for publication, authors can submit it in the format of their choice, and Bentham will convert it into a journal-specific format for them.

If the submission is accepted for publication, Bentham will format it in accordance with the style and format of the journal.

For all online submissions, please provide soft copies ofall the materials (main text in MS Word or Tex/LaTeX), figures/illustrations in TIFF, PDF or JPEG, and chemical structures drawn in ChemDraw (CDX)/ISISDraw (TGF) as separate files, while a PDF version of the entire manuscript must also be included, embedded with all the figures/illustrations/tables /chemical, structures, etc ., It is advisable that the document files related to a manuscript submission should always have the name of the corresponding author as part of the file name, i.e., "Cilli MS text.doc," "Cilli MS Figure 1", etc.

It is imperative that before submission, authors should carefully proofread the files for special characters, mathematical symbols, Greek letters, equations, tables, references and images, to ensure that they appear in a proper format.

References, figures, tables, chemical, structures, etc., should be referred to in the text at the appropriate place where they have been first discussed. Figure legends/captions should also be provided.

Successful electronic submission of a manuscript will be followed by a system-generated acknowledgements to the principal/corresponding author. Any queries therein should be addressed to [email protected]

The journal publishes original research, peer-reviewed mini- and full-length review articles, and written in English. Single topic/ thematic issues may also be considered for publication.

The manuscript should be written in English in a clear, direct and active style. All pages must be numbered sequentially, facilitating in the reviewing and editing of the manuscript.

Any research assistants or other individuals who assisted with the research but do not meet all criteria for authorship, such as those who carried out the literature review, produced, computerized, and analyzed the data, or helped with the language, writing, or proofreading of the article, or offered any comments or suggestions, should be acknowledged. Briefly, everyone who has contributed significantly to the improvement of the paper should be acknowledged. It is recommended to mention the "Declared None" if there is no acknowledgement for the study.

The specific requirements for authorship have been defined by the International Committee of Medical Journal Editors (ICMJE). The examples of authors' contributions are 'designed research/study', 'performed research/study', 'contributed important reagents', 'collected data', 'analyzed data', 'wrote paper' etc. This information must be included in the submitted manuscript as a separate paragraph under the heading ‘Authors' Contribution’. The corresponding author is responsible for obtaining permission from all co-authors for the submission of any version of the manuscript and making any changes in the authorship.

IMPORTANT: An Author Contribution CRediT (Contributor Roles Taxonomy) statement is now a strict requirement for all submissions to Anti-Cancer Agents in Medicinal Chemistry. . This policy aims to address past inconsistencies in the provision of "Author Contribution" statements by authors. Authors are encouraged to clearly define and document their contributions to promote transparency and accountability in the research process.

Compliance with the guidelines of the International Committee of Medical Journal Editors (www.icmje.org) is recommended, in accordance with the patient’s consent for research or participation in a study as per the applicable laws and regulations regarding the privacy and/or security of personal information, including, but not limited to, the Health Insurance Portability and Accountability Act of 1996 ("HIPAA") and other U.S. federal and state laws relating to confidentiality and security of personally distinguishable evidence, the General Data Protection Regulation (GDPR) (EU) 2016/679 and member state implementing legislation, Canada's Personal Information Protection and Electronic Documents Act, India's Information Technology Act and related Privacy Rules, (together "Data Protection and Privacy Laws").

It is the responsibility of the author to ensure that:

Editors may request that authors provide documentation of the formal review and recommendation from the institutional review board or ethics committee responsible for oversight of the study. The editors reserve the right to reject manuscripts that do not comply with the above-mentioned requirements. The author will be held responsible for false statements or failure to fulfill the above-mentioned requirements.

For research involving animals, the authors should indicate whether the procedures followed were in accordance with the standards set forth in the eighth edition of “Guide for the Care and Use of Laboratory Animals” (grants.nih.gov/grants/olaw/guide-for-the-care-and-use-of-laboratory-animals_prepub.pdfpublished by the National Academy of Sciences, The National Academies Press, Washington, D.C.).

Research work on animals should be carried out in accordance with the NC3Rs ARRIVE Guidelines. For In VivoExperiments, please visit https://www.nc3rs.org.uk/arrive-guidelines

Authors should clearly state the name of the approval committee, highlighting that legal and ethical approvals were obtained prior to initiation of the research work carried out on animals, and that the experiments were performed in accordance with the relevant guidelines and regulations stated below.

All experimental research on plants (either cultivated or wild), should comply with international guidelines. The manuscript should include a declaration of compliance of field studies with relevant guidelines and/or relevant permissions or licenses obtained by the IUCN Policy Statement on Research Involving Species at Risk of Extinction and the Convention on the Trade in Endangered Species of Wild Fauna and Flora.

All experimental research on plants (either cultivated or wild), should comply with international guidelines. The manuscript should include a declaration of compliance of field studies with relevant guidelines and/or relevant permissions or licenses obtained by the IUCN Policy Statement on Research Involving Species at Risk of Extinction and the Convention on the Trade in Endangered Species of Wild Fauna and Flora.

Any unusual risks associated with the use of any chemicals, procedures, or equipment used in the work must be explicitly stated by the author in the manuscript, preferably in both the materials and methods section and the declaration section. For more information, visit The World Medical Association (https://www.wma.net/what-we-do/public-health/chemicals)

We strive to promote gender and sex equity in research and adhere to the guidelines of Sex and Gender Equity in Research (SAGER) to ensure inclusivity and rigor of the work. All authors submitting research papers are required to follow the Sex and Gender Equity in Research (SAGER) guidelines. These guidelines are intended to encourage the inclusion of sex and gender considerations in research in order to improve the rigor and relevance of our publications.

The SAGER guidelines for reporting sex and gender information in methodology or study design, data analysis, results, and interpretation of findings are strongly encouraged. Authors of review articles are advised to address the methods used for selecting, locating, extracting, and synthesizing data; systematic reviews are required to do so.

Bentham Science expects all contributors to respect values of justice, benevolence, and autonomy when conducting research. We understand that certain situations such as medical emergencies or humanitarian crises may differ from non-emergency scenarios. Bentham Science recommends that research efforts should not hurt human subjects/respondents or the researchers, and should be conducted with sufficient scientific rigor as permissible in these situations, respectively. Care should be taken to address potential problems faced by persons who may be victims of disasters or involved in a medical emergency. These are vulnerable individuals and their privacy and dignity should be respected. Researchers should make note of this in their research and identify potential issues in their work that may arise because of such situations. Research directed in emergency circumstances should be to the greatest advantage of survivors involved in the research and with the goal of minimizing any future casualties. For guidance, the essential requirements of research in emergency situation are the preservation of human life, wellbeing and security, along with the rights to protection, privacy and confidentiality of subjects.

Unethical behavior and misconduct may be pointed out by anyone to the Editor and Publisher with sufficient evidences. The Editor, in consultation with the Publisher, will initiate investigation against this Unethical misconduct, complete the procedure till an unbiased decision is reached, and maintain confidentiality throughout the process of the investigation. The Author should be given the opportunity to reply to all minor or major accusations.

In case of serious breaches, the employer may be informed where appropriate, by the Editor/Publisher, after reviewing all available information and evidences or after seeking help from experts in that field.

If the manuscript has an individuals’ data, such as personal detail, audio-video material etc., consent should be obtained from that individual.

A specific declaration of such approval and consent-to-disclose form must be made in the copyright letter and in a stand-alone paragraph at the end of the article especially in the case of human studies where inclusion of a statement regarding obtaining the written informed consent from each subject or subject's guardian is a must. The original should be retained by the guarantor or corresponding author. Editors may request to provide the original forms by fax or email.

Post-publication discussions are well-timed and engaging scientific remarks and justifications on research articles published in "Anti-Cancer Agents in Medicinal Chemistry". These remarks must be based on the information concurrent with the original study and not on the scientific advancements being made subsequently.

Manuscript Preparation, Submission & Editorial Process:

• Post-publication discussion should commence with a short paragraph that outlines the summary of the article.
• Authors are advised to avoid using inciting tone in the comments and keep the message clear and concise.
• The main text should not exceed 1200 words with up to 15 references and may include one or two figures and/or tables.
• References should be submitted in the ACS or Vancouver style.
• The correspondents are recommended to contact the original authors first prior to submitting their comments to the journal as this may resolve the issues that may have arisen due to some misunderstanding.
• The correspondence that has been done with the authors should also be submitted as an attachment with the manuscript.

Any queries therein should be addressed to [email protected]

In ACS style, all references should be numbered sequentially [in square brackets] in the text and listed in the same numerical order in the reference section. Superscript in the in-text citations and reference section should be avoided.

In Vancouver style, all references should be numbered sequentially [in square brackets] in the text and listed in the same numerical order in the reference section. Punctuation should be properly applied as mentioned in the examples given above.

The four types of research data policies are mentioned below.

Wherever appropriate and possible, the journal encourages authors to publish data to support their research findings in a public repository. Any datasets mentioned in the article that are available in external repositories should be cited.

How to Cite the Data?

Whether the data was developed by the author(s) or researcher(s), all publicly available data referenced in the preparation of an article should be cited in the text and reference list. The references relating to the data availability should be presented in the following format:

Example: Name of author(s), the title of data set, data repository, document version (e.g., most recent updated version), Digital Object Identifier (DOI), and Bentham Science reference style should be included in data citations.

When authors submit a paper to a journal, the authors agree that the data provided in the publication, including the relevant raw data, will be freely available to any researcher who wants to use these for non-commercial reasons without jeopardising participant anonymity.

Data availability declarations are required under Bentham Science research data policy types.

The statement relating to the data availability should be presented in the following format under a separate section for ‘Availability of Data and Materials’ in the manuscript:

Additional Data Availability Statements

Authors can add or change the statement(s) above, to fit their work the best. Depending on the nature of the research, several assertions may need to be merged.

All datasets on which the paper's conclusions are based must be made accessible to reviewers and readers, according to the journal's rules. Prior to peer review, authors must either deposit their datasets in publicly accessible repositories or provide them as supplementary materials with their submission. For further details, please visit complete guidelines at: http://www.icmje.org/recommendations/browse/publishing-and-editorial-issues/clinical-trial-registration.html

Authors may provide the raw data in connection with a paper for editorial review, and should be prepared to provide public access to such data. if practicable, and should in any event be prepared to retain such data for a reasonable time after publication.

All authors must strictly follow the guidelines below for preparing illustrations for publication in Anti-Cancer Agents in Medicinal Chemistry . If the figures are found to be sub-standard, then the manuscripts will be rejected.

The authors are expected to submit good quality figure(s) in PDF, PPT, MS Word, TIFF or JPEG versions, which, if required, should be improved yourself or by professional graphic designers of your organization/country. You may even consider approaching our contracted service provider Eureka Science for Graphics Enhancement Services.

The Graphics Designing team at Eureka Science can assist in improving the quality of your images at affordable rates. Eureka Science has contracted special rates with us of US $155 for the improvement of up to five figures, with any additional figures being charged at US $25 each.

The quality of Graphic Enhancement Services offered by Eureka Science can be viewed at http://www.eureka-science.com/images/Binder1.pdf, along with valuable feedback on their services at http://www.eureka-science.com/testimonials.php. You may contact Eureka Science at [email protected]

Note: Availing Graphics Enhancement Services does not guarantee acceptance of the manuscript for publication. The final acceptance/decision on the manuscript is taken by the EiC.

Chemical structures must be prepared in ChemDraw (CDX file) and provided as separate file.

Bentham Science Publishers requires that all individuals listed as authors must have made a substantial contribution to the design, performance, analysis, or reporting of the work. The role of authors is judged on the basis of ICMJE and COPE guidelines.

All contributing authors are required to sign a copyright letter, mentioning complete details, including full name, affiliation, email address, ORCID ID and their role in the article. After successful electronic submission of a manuscript, a system-generated acknowledgements will be sent to all authors on their provided email addresses.

The Corresponding Author must provide a final list of authors at the time of submission, ensuring the correct sequence of the names of authors, which will not be considered for any addition, deletion or rearrangement after final submission of the manuscript. The email address of the principal author should be provided with an asterisk. However, the complete address, business telephone numbers, fax numbers and e-mail address of the corresponding author must be stated to receive correspondence and galley proofs. Bentham Science Publishers recommends that all contributors regularly update their profiles on SCOPUS/ORCID and other databases.

The corresponding author must have the approval of all other listed authors for the submission and publication of all versions of the manuscript.

Authors are strongly recommended to use their ORCID ID when submitting an article for consideration. Alternatively, they can acquire an ORCID ID via the submission process. For more information about ORCID IDs, visit here.

At the time of initial submission, the finalized list of authors in the correct sequence should be provided, which will not be changed once the publication process starts.

In exceptional cases, requests for the addition/deletion of an author may be considered by the publisher subject to a) written approval from all co-authors and b) a strong justification (which may or may not be accepted by the Publisher).

Here is some advice from COPE on authorship issues. Bentham strives to follow these guidelines.

Advice on how to spot authorship problems

Corresponding author requests addition of extra author before publication

Corresponding author requests removal of the author before publication

Request for addition of extra author after publication

Request for removal of author after publication

Manuscripts containing language inconsistencies will not be published. Authors should seek professional assistance for correction of grammatical, scientific and typographical errors before submission of the revised version of the article for publication. Professional editing services may also be sought by the team available at Bentham Science.

Extend the scope and visibility of your research by creating an animated abstract. Bentham Science has collaborated with Focus Medica, one of the world’s largest publishers of expert animated atlases and videos in medicine and science.

An animated abstract will help summarise the essential discoveries/ key findings of your published research or review article. Each professionally produced full-coloured animated abstract in video format (length 3 – 5 minutes) is accompanied by an English spoken or foreign language commentary. The animated abstract will be published online along with the published article.

The payment for an animated abstract will be US $1320. Initially, an advance amount of US $800 will be payable to the Publisher to start work on the Animated Abstract, while the balance of US $520 will be payable on completion of the Animated Abstract.

Authors who opt for the “Animated Abstract” option and also wish to have their article made available on an “Open Access Plus (Gold Open Access)” basis will be entitled to a 50% discount only on the Animated Abstract fee and, in addition, pay the normal Open Access Plus (Gold Open Access) fee.

Authors will be asked whether they wish to opt-in for this paid animated abstract service, and if not, the article will be published as normal. Animated abstracts are available as open access (free viewing) for maximum visibility and awareness to readers at anytime, anywhere. The animated abstracts are licensed under the terms of the Creative Commons Attribution – NonCommercial-NoDerivatives 4.0 International Public License (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/

For a sample of an animated abstract please access here https://www.benthamscience.com/pages/animated-abstract-video

Bentham Science offers discounts to those corresponding authors who are based in low-income countries*.

The authors who wish to avail this offer should request for a discount at the time of submission of their manuscripts to Bentham Science.

All papers submitted to Bentham Science for publication are immediately subjected to preliminary editorial scrutiny by the Editorial Staff and Editor-in-Chief in connection with their suitability. The Editor-in-Chief determines if the manuscript:

(a) falls within the scope of the journal and

(b) meets the editorial criteria of Bentham Science Publishers in terms of originality and quality.

Manuscripts that appear to be suitable are then subjected to double-blind peer review by, usually two to three, neutral eminent experts. The services of eminent international experts are sought through invitations to conduct the peer review of a submitted manuscript, keeping in view the scope of the manuscript and the expertise of the reviewers. The identities of both the reviewer and author are kept undisclosed to each other, ensuring anonymity and maintaining confidentiality throughout the entire review procedure. The anonymity of reviewers ensures an objective and unbiased assessment of the manuscript by the reviewers.

Before sending the manuscripts to reviewers, Bentham Science seeks consent from potential reviewers about their availability and willingness to review. Correspondence between the editorial office of the journal and the reviewers is kept confidential. The reviewers are expected to provide their reports in a timely fashion since a prompt review leads to the timely publication of a manuscript which is beneficial not only to the authors but to the scientific community as well.

The editorial process and peer-review workflow for each journal are taken care of by a team of Senior Editors, Editorial Board Members (EBMs) and dedicated Journal managers who have the required expertise in their specific fields.

Bentham Science Publishers carries out independent reviews of all articles. The reviewers are selected according to their expertise, from our, regularly updated, referee database.

On the basis of reviewer comments, the Editors may recommend acceptance, revision or rejection of a manuscript.

After a review of the manuscript by at least two or three independent experts, in addition to the views of the Editor, the decision is relayed to the authors, which may be categorized as:

If an article receives two contradictory reports, the Editor-in-Chief retains the right to request additional comments and the discretion to make the final decision without waiting for additional reports, taking into consideration the content and conclusions presented in all reports. This proactive approach ensures promptness in conveying the Editor's decision, thereby facilitating swift communication with the author.

Bentham Science requests not to have the manuscripts peer-reviewed by those experts who may have competing interest with the author(s) of a submitted manuscript. It is not possible for Editors to be aware of all competing interests; it is therefore expected that the reviewers would inform the Editor-in-Chief/Handling Editor if they notice any potential competing interest during the course of review of a manuscript. Moreover, the reviewers are expected to inform the Editors or editorial office of the journal if they have a conflict of interest in carrying out the review of a manuscript submitted by any author/contributor of the manuscript.

The authors are usually requested to resubmit the revised paper within 15 days and it will then be returned to the reviewers for further evaluation. The publishers normally allow one round of revision and, in exceptional cases, a second round of revision may be allowed. If further revision is needed, then the manuscript is rejected and the author is requested to resubmit the manuscript for fresh processing.

The final decision regarding acceptance or rejection is that of the Editor-in-Chief, depending on the quality of the revision and his assessment of the quality of the manuscript. In rare cases, manuscripts recommended for publication by the referees may be rejected in the final assessment by the Editor-in-Chief.

The time frame for revision of any article may vary from one to four weeks, depending on the nature of the revision required (minor or major). However, authors who need extra time for revision should consult the Editor-in-Chief/Handling Editor with valid reasons and the submission date of the revised manuscript may be extended if the request is genuine.

After the successful completion of the review and acceptance of the article, the articles are typeset and proofs are dispatched to authors for any corrections prior to final publication.

Plagiarism means copying or paraphrasing another writer's content, be it a text, a result or an observation, and stating it as one's own, without citing a reference to the original source. Therefore, authors should acknowledge and cite references to the work of other scientists in their manuscripts. The author should ensure that all the sources are authentic and that there is no discrepancy in the content of the manuscript.

Bentham Science is vigilant in checking and identifying the primary sources of the data within the content by using the iThenticate software to detect instances of overlapping and similarity of text in submitted manuscripts. iThenticate software verifies the content against a database of periodicals, materials on the Internet, and a comprehensive article database. The software generates a similarity report in percentage that matches the article in process and the published material. This similarity is further scrutinized for suspected plagiarism according to the publisher's Editorial Policies. The generated report comprises the overall percentage of the content reused.

To ensure the scholarly integrity of every article, Bentham Science will publish post-publication notices. The authors of the published articles, or those who have submitted the manuscripts with false information, or fabricated the supporting data or images, will be liable for sanctions, and their papers will be retracted. For further details, please visit complete guidelines at: https://www.benthamscience.net/fabricating-stating-false-information

Bentham Science is a publishing partner of Kudos. All authors who publish in this journal will receive an invitation to join the Kudos platform, an entirely free service for authors. Kudos enables authors to help broaden their audience and readers, increase their professional profile and reputation, and establish an impact for their publications. The website link is www.growkudos.com.

Kudos provides a free platform to researchers to have their publications accessible, read and cited across multiple networks and channels available to researchers for the dissemination of their work. It takes on average 15 minutes and leads to 23% higher growth in full-text downloads.

Authors are encouraged to explain their work in clear English and to attract researchers of the relevant communities, share a trackable link that you can email to your existing network of contacts, or share on social media and academic websites, and track how well the articles are performing through the summary of views, downloads, citations, and altmetrics on the Kudos dashboard.

Authors may also use the new shareable PDF (S-PDF) service. The S-PDF provides researchers with the means to write and share a high-level overview for each of their publications. Kudos thereby provides researchers, and their publishers and institutions, with a rich understanding of which channels and activities are most effective for broadening the reach and impact of published science.

Committee on Publication Ethics (COPE) is an advisory body that ensures the highest standards of editorial practice in scholarly publishing, by providing guidance to editors and publishers in all aspects of publication ethics.

Anti-Cancer Agents in Medicinal Chemistry is committed to upholding ethical standards in scholarly publishing. This journal is affiliated with COPE and adheres to its guidelines. To learn more about COPE guidelines, visit COPE website.

Bentham Science Publishers is pleased to offer electronic publication of accepted papers prior to scheduled publication. These peer-reviewed papers can be cited using the date of access and the unique DOI number. Any final changes in manuscripts will be made at the time of print publication and will be reflected in the final electronic version of the issue. Articles in Early View may be ordered by pay-per-view from the relevant links given by each article stated via the Early View

Generally, the editorial decisions are not reverted. However, authors who think that their manuscript was rejected due to a misunderstanding or mistake may seek an explanation for the decision. Appeals must give sound reasoning and compelling evidence against the criticism raised in the rejection letter. A difference of opinion as to the interest, novelty, or suitability of the manuscript for the journal will not be considered as an appeal. The EIC and other relevant editors will consider the appeal and the decision thereafter taken by the journal will be deemed final. Acceptance of the manuscript is not guaranteed even if the journal agrees to reconsider the manuscript, and the reconsideration process may involve previous or new reviewers or editors and substantive revision.

Authors who wish to make a complaint should refer them to the Editor-in-Chief of the journal concerned. Complaints to the Publisher may be emailed to [email protected]