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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Volume 20, 18 Issues, 2020
ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.

Each issue contains a series of timely in-depth/mini reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.

Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.

Anti-Cancer Agents in Medicinal Chemistry

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Volume 20

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Number 13



Biography   Open Access



Research Article

Molecular Docking, Antioxidant, Anticancer and Antileishmanial Effects of Newly Synthesized Quinoline Derivatives

, 20(13): 1516 - 1529

Zoonish Malghani, Arif-Ullah Khan*, Muhammad Faheem, Muhammad Z. Danish, Humaira Nadeem, Sameen F. Ansari and Madeeha Maqbool


DOI: 10.2174/1871520620666200516145117


Research Article



Research Article



Research Article



Research Article



Research Article

The Apoptosis Mechanism of Epirubicin Combined with BCG on Human Bladder Cancer Cells

, 20(13): 1571 - 1581

Yang Luo, Xiaoyi Fu, Bin Han, Fafu Zhang, Lihong Yuan, Hongsheng Men, Shulin Zhang, Sujuan Tian, Bin Dong* and Minjie Meng*


DOI: 10.2174/1871520620666200502004002


Research Article



Anti-Cancer Agents in Medicinal Chemistry, Volume 20 (2020) - Number 16


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 20 (2020) - Number 15


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 20 (2020) - Number 14


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Anti-Cancer Activity of Curcumin on Multiple Myeloma


Hamed Mirzaei*, Hossein Bagheri, Faezeh Ghasemi, Jaber M. Khoi, Mohammad H. Pourhanifeh, Yvan V. Heyden, Erfan Mortezapour, Ali Nikdast, Philippe Jeandet, Haroon Khan and Amirhossein Sahebkar


DOI: 10.2174/1871520620666200918113625
View Abstract



Identification of 3-Bromo-1-Ethyl-1H-Indole as a Potent Anticancer Agent with Promising Inhibitory Effects on GST Isozymes


Can Yılmaz, Sevki Arslan*, Dogukan Mutlu, Metin Konus, Abdussamet Kayhan, Aslıhan KurtKızıldoğan, Çiğdem Otur, Omriye Ozok and Arif Kivrak


DOI: 10.2174/1871520620666200918111940
View Abstract


Pharmaceutical aspects of green synthesized silver nanoparticles: A boon to cancer treatment


Vijay Mishra*, Pallavi Nayak, Manvendra Singh, Murtaza M. Tambuwala, Alaa A. Aljabali, Dinesh K. Chellappan and Kamal Dua


DOI: 10.2174/1871520620666200918111024
View Abstract


Antiproliferative and Genotoxic Action of an Underexploited Organoteluran Derivative on Sarcoma 180 Cells


Maria L.L. Barreto do Nascimento, Antonielly Campinho dos Reis, José V.O. Santos, Helber A. Negreiros, Felipe C. Carneiro da Silva, Paulo M.P. Ferreira, Juan C.R. Gonçalves, Dalton Dittz, Débora C. Braz, Adriana M.V. Nunes, Rodrigo L.O.R. Cunha, Ana A.C. MeloCavalcante and João Marcelo de Castro e Sousa*


DOI: 10.2174/1871520620666200918110152
View Abstract



The Chemosensitizing Role of Metformin in Anticancer Therapy


Zhimin Tang, Nan Tang, Shanshan Jiang, Yangjinming Bai, Chenxi Guan, Wansi Zhang, Shipan Fan, Yonghong Huang, Hui Lin and Ying Ying*


DOI: 10.2174/1871520620666200918102642
View Abstract



Anti-Cancer Effect of Gingerol in Cancer Prevention and Treatment


Sana Nafees, Md. Zafaryab, Syed H. Mehdi, Bushra Zia, Moshahid A. Rizvi and Md. Asad Khan*


DOI: 10.2174/1871520620666200918100833
View Abstract


A Study on the Effect and Mechanism of Xiaoaiping (XAP) Injection and S-1 Combination Therapy in Inhibiting the Invasion and Metastasis of Human GC Cells


Peiyu Wen*, Haibo Wang, Tengyang Ni, Xiaojun Dai, Zewen Chu, Shuang Ma, Liangliang Xiang, Zhen Zhou, Yayun Qian, Masataka Sunagawa and Yanqing Liu


DOI: 10.2174/1871520620666200918100422
View Abstract


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice


Concise Synthesis of 1,1-Diarylvinyl Sulfones and Investigations on their Antiproliferative Activity via Tubulin Inhibition

, 2020; 20(12): 1469 - 1474

Lavanya Reddy, Suja T. Dharmabalan*, Kanakaraju Manupati, Ragini Yeeravalli, Lakshmi D. Vijay, Kavitha Donthiboina, Vadithe Lakshma Naik and Amitava Das


DOI: 10.2174/1871520620666200423075630










Insights into Nano-Photo-Thermal Therapy of Cancer: The Kinetics of Cell Death and Effect on Cell Cycle

, 2020; 20(5): 612 - 621

Mousa Tabei, Elham Zeinizade, Jaber Beik, S. Kamran Kamrava, Zahra Nasiri, Habib Ghaznavi* and Ali Shakeri-Zadeh*


DOI: 10.2174/1871520620666200129111332



Open Access Articles

The Killing of Human Neuroblastoma Cells by the Small Molecule JQ1 Occurs in a p53-Dependent Manner

, 2020; 20(13): 1613 - 1625

Joseph Mazar*, Caleb Gordon, Varun Naga and Tamarah J. Westmoreland




Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells

, 2020; 20(6): 687 - 699

Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang




Possible Enhancement of Photodynamic Therapy (PDT) Colorectal Cancer Treatment when Combined with Cannabidiol

, 2020; 20: 1 - 12 (E-Pub Ahead of Print)

Nkune W. Nkune, Cherie A. Kruger* and Heidi Abrahamse





Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis

, 2019; 19(10): 1253 - 1261

Naipeng Cui, Dan-Dan Lin, Yang Shen, Jian-Guo Shi, Bing Wang, Ming-Zhi Zhao, Lishuang Zheng, Hua Chen* and Jian-Hong Shi*





New Strategies for Therapeutic Cancer Vaccines

, 2019; 19(2): 213 - 221

Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang




Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*





Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi







Most Cited Articles


Research Article

Synthesis and biological evaluation of novel heterocyclic imines linked coumarin- thiazole hybrids as anticancer agents

, 2019; 19(4): 557-566.

Nerella S. Goud, Mahammad S. Ghouse, Jatoth Vishnu, Jakkula Pranay, Ravi Alvala, Venu Talla, Insaf A. Qureshi and Mallika Alvala*


DOI: 10.2174/1871520619666190207140120


Review Article

Phytochemicals in anticancer drug development

, 2019; 19(2): 172-183.

Rohit Dutt, Vandana Garg, Naveen Khatri and Anil K. Madan*


DOI: 10.2174/1871520618666181106115802


Review Article

Crocetin and crocin from saffron in cancer chemotherapy and chemoprevention

, 2019; 19(1): 38-47.

Alessandro Colapietro, Andrea Mancini, Anna Maria D'Alessandro and Claudio Festuccia*


DOI: 10.2174/1871520619666181231112453



Research Article

Let-7a could serve as a biomarker for chemo-responsiveness to docetaxel in gastric cancer

, 2019; 19(3): 304-309.

Najibeh Shekari, Faezeh Asghari, Navideh Haghnavaz, Dariush Shanehbandi, Vahid Khaze, Behzad Baradaran and Tohid Kazemi*


DOI: 10.2174/1871520619666181213110258


Research Article

Novel inhibitors of DNA repair enzyme TDP1 combining monoterpenoid and adamantane fragments

, 2019; 19(4): 463-472.

Evgenii S. Mozhaitsev, Alexandra L. Zakharenko, Evgeniy V. Suslov*, Dina V. Korchagina, Olga D. Zakharova, Inna A. Vasil'eva, Arina A. Chepanova, Ellena Black, Jinal Patel, Raina Chand, Jóhannes Reynisson, Ivanhoe K.H. Leung, Konstantin P. Volcho, Nariman F. Salakhutdinov and Olga I. Lavrik


DOI: 10.2174/1871520619666181207094243



Research Article

[10]-gingerol affects multiple metastatic processes and induces apoptosis in MDA-MB-231 breast tumor cells

, 2019; 19(5): 645-654.

Angelina M. Fuzer, Ana C.B.M. Martin, Amanda B. Becceneri, James A. da Silva, Paulo C. Vieira and Marcia R. Cominetti*


DOI: 10.2174/1871520618666181029125607


Research Article

What makes species productive of anti-cancer drugs? Clues from drugs’ species origin, druglikeness, target and pathway

, 2019; 19(2): 194-203.

Xiaofeng Li, Xiaoxu Li, Yinghong Li, Chunyan Yu, Weiwei Xue, Jie Hu*, Bo Li, Panpan Wang and Feng Zhu*


DOI: 10.2174/1871520618666181029132017


Review Article

Immunotherapy in patients with recurrent and metastatic squamous cell carcinoma of the head and neck

, 2019; 19(3): 290-303.

Izabela Łasińska*, Tomasz Kolenda, Anna Teresiak, Katarzyna M. Lamperska, Łukasz Galus and Jacek Mackiewicz


DOI: 10.2174/1871520618666180910092356



Review Article

Garlic and its active compounds: A potential candidate in the prevention of cancer by modulating various cell signalling pathways

, 2019; 19(11): 1314-1324.

Saleh A. Almatroodi, Mohammed A. Alsahli, Ahmad Almatroudi and Arshad H. Rahmani*


DOI: 10.2174/1871520619666190409100955



Research Article

Hydroxytyrosol and oleuropein inhibit migration and invasion of MDA-MB-231 triple-negative breast cancer cell via induction of autophagy

, 2019; 19(16): 1983-1990.

Hui-Yuan Lu*, Jian-Sheng Zhu, Zhan Zhang, Wei-Jian Shen, Shan Jiang, Yun-Feng Long, Bin Wu, Tao Ding, Fei Huan and Shou-Lin Wang


DOI: 10.2174/1871520619666190722101207



Most Accessed Articles


Inhibitors of Cancer Stem Cells

, 2016; 16(10): 1230-1239.

María E. García-Rubiño, César Lozano-López and Joaquín M. Campos


DOI: 10.2174/1871520616666160330104715



Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells

, 2020; 20(6): 687-699.

Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang


DOI: 10.2174/1871520620666200213102849


Chemotherapeutic Targeting of Cell Death Pathways

, 2012; 12(3): 226-238.

Sylvia Mansilla, Laia Llovera and Jose Portugal


DOI: 10.2174/187152012800228805


The Warburg Effect and the Hallmarks of Cancer

, 2017; 17(2): 164-170.

Khalid O. Alfarouk, Claudiu T. Supuran and Laurent Schwartz


DOI: 10.2174/1871520616666161031143301


Role of Stem Cells in Normal Liver and Cancer

, 2011; 11(6): 522-528.

Chi Keung Lau, Zhen Fan Yang and Sheung Tat Fan


DOI: 10.2174/187152011796011091


Anticancer Potential of Dietary Natural Products: A Comprehensive Review

, 2020; 20(2): 122-236.

Rumana Ahmad*, Mohsin A. Khan, A.N. Srivastava, Anamika Gupta, Aditi Srivastava, Tanvir R. Jafri, Zainab Siddiqui, Sunaina Chaubey, Tahmeena Khan and Arvind K. Srivastava


DOI: 10.2174/1871520619666191015103712



Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer

, 2020; 20(1): 70-83.

Mohamed A. Tantawy, Farid M. Sroor*, Magda F. Mohamed*, Mostafa E. El-Naggar, Fatma M. Saleh, Hamdi M. Hassaneen and Ismail A. Abdelhamid*


DOI: 10.2174/1871520619666191024121116



Editor-in-Chief

Yong Sang Song
Seoul National University
College of Medicine
Seoul
(South Korea)
View Full Editorial Board

Journal History

Current Medicinal Chemistry - Anti-Cancer Agents was launched in 2001 and later renamed in 2006 as Anti-Cancer Agents in Medicinal Chemistry.

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