Title:Opioid Free Anaesthesia and Cancer
Volume: 25
Issue: 28
Author(s): Alfredo Malo-Manso*, Aida Raigon-Ponferrada*, Julia Diaz-Crespo, Juan J. Escalona-Belmonte, Jose Cruz-Mañas and Jose L. Guerrero-Orriach
Affiliation:
- Department of Anaesthesiology, Virgen de la Victoria University Hospital, Malaga,Spain
- Department of Anaesthesiology, Virgen de la Victoria University Hospital, Malaga,Spain
Keywords:
Opioid free anaesthesia, cancer, opioids, anaesthesia, metastases, recurrence, oncology, surgery.
Abstract:
Opioid-free anesthesia is revolutionizing anesthetic practices for its potential benefits in selected patients.
Opioid-free anesthesia represents a step forward in anesthetic practice as it has been suggested to provide
potential clinical benefits for selected patients. Opioid-free anesthesia spares the use of opioids and involves the
administration of multiple adjuvant anesthetics, which may have an impact on cancer progression. All this have
added to the growing interest in the immune response to anesthetics, making opioid-free anesthesia a promising
avenue for future research.
Assessing the role of anesthetics in immunomodulation in the surgical setting is challenging, and results are often
contradictory. Indeed, there is a scarcity of data of studies on humans, which hinder the interpretation of results.
However, promising evidence has been published that cancer progression can be delayed by the administration of
specific anesthetic agents.