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General Review Article

镧，镓及其对氧化应激的影响

卷 26, 期 22, 2019

页: [4280 - 4295] 页: 16

弟呕挨: 10.2174/0929867326666190104165311

价格: $65

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摘要

金属在活生物体中扮演的角色已得到充分确立，并需要进行广泛的研究。其中一些参与电子交换反应。由于氧化应激，此类反应会导致自由基产生，从而对生物系统产生不利影响。由于“非生物”金属在现代文明中起着至关重要的作用，因此也值得一提。镧系元素（Ln）被广泛用于现代技术中。结果，人类对它们的暴露正在增加。它们具有许多已建立的医学应用，并且因其潜在的抗病毒，抗癌和抗炎特性而受到广泛研究。目前的审查集中在镧（La）及其对氧化应激的影响。镓（Ga）是另一种在现代高科技中广泛使用的金属。在某些方面，它显示出与La的某些相似之处，因此它也是本综述的主题。两种金属均表现出离子拟态，使其能够特异性靶向恶性细胞，引发细胞凋亡，从而使其简单的盐和配位复合物有望成为未来抗癌药物的候选物。

关键词: 镧，镓，氧化应激，抗氧化剂，抗癌剂，细胞凋亡。

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