Title:Advances in Carbon Based Nanomaterials for Bio-Medical Applications
Volume: 26
Issue: 38
Author(s): Tejendra Kumar Gupta, Pattabhi Ramaiah Budarapu*, Sivakumar Reddy Chappidi, Sudhir Sastry Y.B., Marco Paggi and Stephane P. Bordas
Affiliation:
- School of Mechanical Sciences, Indian Institute of Technology Bhubaneswar, Bhubaneswar 752050,India
Keywords:
Carbon based nanomaterials, functionalization, drug delivery, biomedicine, toxicity, hybridization.
Abstract: The unique mechanical, electrical, thermal, chemical and optical properties of carbon
based nanomaterials (CBNs) like: Fullerenes, Graphene, Carbon nanotubes, and their derivatives
made them widely used materials for various applications including biomedicine.
Few recent applications of the CBNs in biomedicine include: cancer therapy, targeted drug
delivery, bio-sensing, cell and tissue imaging and regenerative medicine. However, functionalization
renders the toxicity of CBNs and makes them soluble in several solvents including
water, which is required for biomedical applications. Hence, this review represents the complete
study of development in nanomaterials of carbon for biomedical uses. Especially, CBNs
as the vehicles for delivering the drug in carbon nanomaterials is described in particular. The
computational modeling approaches of various CBNs are also addressed. Furthermore, prospectus,
issues and possible challenges of this rapidly developing field are highlighted.