Title:Novel Topical Nanocarriers for Treatment of Psoriasis: An Overview
Volume: 24
Issue: 33
Author(s): Ankita Dadwal, Neeraj Mishra and Raj K. Narang*
Affiliation:
- Department of Pharmaceutics; I.S.F. College of Pharmacy, Ghal Kalan, Ferozpur, G.T road, Moga- 146001, Punjab,India
Keywords:
Dermal drug delivery, liposomes, microemulsions, nanoemulsion, nanoparticles, phospholipids.
Abstract: Background: Psoriasis is an autoimmune disease of the skin with lapsing episodes of hyperkeratosis,
irritation and inflammation. Numerous methodologies and utilization of different antipsoriatic drugs with various
activity methods and routes of administration have been investigated to treat this terrifying sickness. In any case,
till date, there is no remedy for psoriasis because of the absence of an ideal carrier for effective and safe delivery
of antipsoriatic drugs.
Objective: Among the different methods of medications for psoriasis, in the greater part of patients, topical treatment
is most commonly utilized. For topical formulations, utilization of conventional excipients could fill the
need just to a restricted degree. With the revelation of more up to date biocompatible and biodegradable materials
like phospholipids, and Novel drug delivery technologies like liposomes, solid lipid nanoparticles (SLNs), microemulsions,
and nanoemulsions, the possibility to enhance the efficiency and safety of the topical products has
expanded to a great extent. Understanding the topical delivery aspects and that of outlining and creating different
carrier systems have been enhanced that got further novelty to this approach.
Conclusion: Present review is an attempt to contemplate on psoriasis as far as improved comprehension of the
dermal delivery perspectives and at present accessible treatment alternatives, significant preventions in psoriasis
treatment, late advancements in the conveyance of different antipsoriatic drugs through novel colloidal drug
transporters.
