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Review Article

用于神经元相关应用的光触发药物输送系统

卷 26, 期 8, 2019

页: [1406 - 1422] 页: 17

弟呕挨: 10.2174/0929867325666180622121801

价格: $65

摘要

材料，化学和遗传学的发展创造了大量用于神经科学研究中向神经元递送抗生素，神经肽或其他药物的系统，并且还在神经元相关应用中提供了重要且强大的工具。尽管这些药物递送系统可以促进神经科学研究的进步，但是由于各种缺点，例如难以将递送分子或药物控制到目标区域，以及以可预测的方式释放它们的麻烦，它们仍然具有有限的应用。光学和药物递送系统的组合具有很大的潜力来解决这些问题，并通过由光触发的非凡的时空选择性将分子或药物递送至神经系统。在这篇综述中，我们将介绍神经科学研究中光触发药物输送系统的发展及其神经元相关应用，包括调节神经活动，治疗神经疾病和诱导神经再生。

关键词: 光触发药物输送系统，神经元，微流体系统，水凝胶，纳米针，脂质体，光学镊子，光遗传学。

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