Title:Honey: An Effective Regenerative Medicine Product in Wound Management
Volume: 26
Issue: 27
Author(s): Simona Martinotti*, Marcela Bucekova , Juraj Majtan and Elia Ranzato
Affiliation:
- DiSIT-Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, Alessandria, 15121,Italy
Keywords:
Honey, wound repair, regenerative medicine, tissue, immunomodulator, wound healing.
Abstract:
Honey has successfully been used in the treatment of a broad spectrum of injuries
including burns and non-healing wounds. It acts as an antibacterial and anti-biofilm agent
with anti/pro-inflammatory properties. However, besides these traditional properties, recent
evidence suggests that honey is also an immunomodulator in wound healing and contains several
bee and plant-derived components that may speed up wound healing and tissue regeneration
process. Identifying their exact mechanism of action allows better understanding of
honey healing properties and promotes its wider translation into clinical practice.
This review will discuss the physiological basis for the use of honey in wound management,
its current clinical uses, as well as the potential role of honey bioactive compounds in dermal
regenerative medicine and tissue re-modeling.