Title: Gene Regulation in Cancer Gene Therapy Strategies
Volume: 10
Issue: 20
Author(s): Ian Scanlon, Panos Lehouritis, Ion Niculescu-Duvaz, Richard Marais and Caroline J. Springer
Affiliation:
Keywords:
transcriptional control, regulated expression, gdept, suicide gene
Abstract: Regulation of expression in gene therapy is considered to be a very desirable goal, preventing toxic effects and improving biological efficacy. A variety of systems have been reported in an ever widening range of applications, this paper describes these systems with specific reference to cancer gene therapy.