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Review Article

用于光声成像引导光疗的有机纳米诊断学

卷 26, 期 8, 2019

页: [1389 - 1405] 页: 17

弟呕挨: 10.2174/0929867324666170921103152

价格: $65

摘要

包括光热疗法（PTT）和光动力疗法（PDT）在内的光疗法已成为癌症治疗的前卫策略之一。 光声（PA）成像是一种新的混合成像模式，对于具有深部组织穿透和高空间分辨率的生物过程的实时体内监测显示出巨大的希望。 为了提高治疗效果，减少副作用并最大限度地减少过度用药的可能性，有必要使用成像和诊断方法来确定理想的治疗窗并跟踪治疗结果。 在这方面，具有进行PA成像和PTT / PDT的能力的纳米诊断学正在出现。 本综述总结了近红外（NIR）染料和半导体聚合物纳米粒子（SPNs）等有机纳米材料在PA成像引导癌症光疗中的最新进展，并阐述了它们目前在临床应用中面临的挑战和潜力。

关键词: 光热疗法，光动力疗法，光声成像，纳米疗法，近红外染料，半导体聚合物。

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