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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Gene Delivery with Organic Electronic Biomaterials

Author(s): Kathryn F.A. Clancy and John G. Hardy*

Volume 23, Issue 24, 2017

Page: [3614 - 3625] Pages: 12

DOI: 10.2174/1381612823666170710124137

Price: $65

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Abstract

Gene therapy may be capable of treating a variety of diseases, a prerequisite of which is the successful delivery of polynucleic acids (e.g., DNA, RNA) to a patient’s cells. Delivery can be achieved technologically (e.g., using electroporation), using viruses (natural gene delivery vectors) or non-viral vectors (e.g., lipids, nanoparticles, polymers). This article aims to give the reader an overview of the use of organic electronic materials (i.e., fullerenes, graphenes and conjugated polymers) as non-viral gene delivery vectors.

Keywords: Organic electronics, carbon nanotubes, fullerene, graphene, conjugated polymer, gene delivery, gene therapy, biodegradable.

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