Title:A Brief Overview on Chemistry and Biology of Benzoxepine
Volume: 14
Issue: 9
Author(s): Naveen Kuntala, Jhonsee R. Telu, Jaya S. Anireddy and Sarbani Pal*
Affiliation:
- Department of Chemistry, MNR Degree & PG College, Kukatpally, Hyderabad-500072,India
Keywords:
Benzoxepine, heterocycles, synthesis, medicinal importance, chemistry, biology.
Abstract: Background: The present review article is related to the synthesis and medicinal
importance of benzoxepine and its derivatives. The study of heterocycles is an evergreen field in the
branch of organic / medicinal chemistry and always attracts the attention of chemists working not
only in the area of organic synthesis but also in natural products.
Methodology: The derivatives of benzoxepine exhibit a wide range of pharmacological properties
such as antibacterial, anticancer, antioxidants, anti-inflammatory, anti-diabetic, antiviral, antiproliferative,
antituberculosis, antispermetogenic and antipsychotic activities. Consequently, their syntheses have
attracted significant interest. Various methodologies have been developed for the synthesis and
functionalization of this class of compounds.
Conclusion: In the present article, the relevant and recent advances in the field will be briefly
covered.