Title:Paeonol, a Powerful Natural Product with Broad Biological Spectra by Inhibiting Inflammatory Pathway
Volume: 2
Issue: 2
Author(s): Bixi Tang, Cai-Yun Peng, Kwame Oteng Darko, Ting Tao, Yanjun Huang, Qiongli Su and Xiaoping Yang
Affiliation:
Keywords:
Antitumor, anti-inflammatory, anticancer, in vivo, in vitro, paeonol.
Abstract: Paeonol, a naturally existing compound found in Chinese traditional medicinal
herb Cortex Moutan, the root bark of Paeonia suffruticosa Andr., has shown anticancer, antiinflammatory
and anti-cardiovascular disease activities. These biological activities largely
rely on the mechanisms underlying. It has been shown that these biological activities of
paeonol are largely related to the inflammatory NF-κB cell signaling pathways. In this minireview,
we are the first to summarize biological activities and associated pathways of paeonol.