Title:Quaternary Ammonium Ionic Liquid as a Dual Solvent-Catalyst in Biginelli Reaction
Volume: 13
Issue: 7
Author(s): Imane Tebabel, Taoues Boumoud, Boudjemaa Boumoud and Debache Abdelmadjid
Affiliation:
Keywords:
4-Aryl-5-ethoxycarbonyl-3, 4-dihydro-6-methylpyrimidin-2(1H)-ones, Biginelli compounds, Brønsted acidic ionic
liquid, dual solvent-catalyst, L-valine sulfate 1:1, multi-component reactions.
Abstract: Multi-component reactions (MCRs) utilizing unconventional solvents like ionic liquids have
become a new research direction that has emerged as an important facet of green chemistry. The present
work deals constructively with the MC one pot synthesis of 4-aryl-5-ethoxycarbonyl-3,4-dihydro-6-
methylpyrimidin-2(1H)-ones using L-valine sulfate 1:1 [H-Val][HSO4], a cheap, non-corrosive, and
eco-friendly ionic liquid as a dual solvent-catalyst.
