Title:Alginate Based Nanocarriers for Drug Delivery Applications
Volume: 22
Issue: 22
Author(s): Sougata Jana, Kalyan Kumar Sen and Arijit Gandhi
Affiliation:
Keywords:
Alginate, Nanoparticles, Nano-aggregates, Nanocapsules, Nanospheres, Drug delivery.
Abstract: Background: Now a day’s natural polymer based nanoparticulate system have been widely studied as
particulate vehicles in the bio-medical and pharmaceutical area. Alginate, a natural biopolymer show good biodegradability,
biocompatibility and non toxic, has received attention to utilise as a carrier for preparation of polymeric
nanoparticles. Chemically and physically alginate can modified easily and obtained various structure having
various properties, and versatile applications. Various properties and structure such as biodegradability, gelling
property, mechanical strength and cell affinity can be obtained through combination of alginate with other biopolymers,
immobilization of specific molecules such as sugar molecules and peptide through chemical or physical
cross-linking. Conclusion: In this article, we report different method of preparation of alginate nanoparticles, and
also focus on recent advances of nanoparticles made of alginate and its modified form in the field of drug delivery
applications.
