Title:Acute Renal Failure in Different Malignant Tumors
Volume: 23
Issue: 19
Author(s): Sanja Radojevic-Skodric, Ljiljana Bogdanovic, Milena Jovanovic, Ivana Baralic, Zoran Dzamic, Ron Gordon, Simona Ognjanovic and Gordana Basta-Jovanovic
Affiliation:
关键词:
急性肾功能衰竭，肿瘤溶解综合征，肝细胞癌，多发性骨髓瘤，淋巴瘤。
摘要: Acute renal failure (ARF) represents a severe complication of malignancies,
that causes significant morbidity and mortality. ARF is a common part
of multiple organ dysfunction in critically ill patients with cancer with reported
mortality rates from 72% to 85% in patients who need renal replacement therapy.
The pathways leading to ARF in cancer patients are common to the development
of ARF in other conditions. However, certain factors leading to the development
of ARF may be associated to the tumor or to the tumor therapy. The
purpose of this review is to give specific aspects of renal disease in critically ill
cancer patients (CICPs), to overview the causes of ARF in CICPs and to describe
recent progress in the management of these complications, including
treatment toxicity and bone marrow transplantation (BMT). The prevention of ARF is obligatory
and therefore the possible treatments of ARF in CICPs are also discussed.
