Title:Anti-Psoriasis Agents from Natural Plant Sources
Volume: 23
Issue: 12
Author(s): Marco Bonesi, Monica Rosa Loizzo, Eugenio Provenzano, Francesco Menichini and Rosa Tundis
Affiliation:
Keywords:
Psoriasis, skin, botanicals, medicinal plants, mechanism of action.
Abstract: Psoriasis is a chronic inflammatory immune-mediated skin disease. It affects most
races, does not have any sexual predilections and can manifest at any age of life. Psoriasis is
more frequent in certain racial groups and geographical areas. For these reasons, both genetic
and environmental factors could be considered. In this review, we discuss promising
natural compounds, their molecular targets and mechanisms, which may help the further design
of new anti-psoriasis agents. Literature documents the widespread use of herbal remedies
worldwide, and the presence of some phytochemicals supports the efficacy of some botanical treatments.
The research on natural products has greatly contributed to the progress in the treatment of skin diseases such
as psoriasis and many of these compounds are now being used. Understanding the mechanism of these molecules
will contribute to the development of more specific preventive strategies for the treatment of psoriasis.
