Abstract
Currently, many novel therapies are available for physicians treating cancer; some of them are associated with adverse cardiac events. One of the most worrisome cardiac event is QT prolongation, which is a risk factor for developing the potentially fatal torsade de pointe. Many classes of drugs, both anticancer and concomitant agents, are involved in this issue. We report a review of old and new commonly used agents with torsadogenic potential.
Keywords: Adverse cardiac events, cancer, QT prolongation, through QT study, torsade de point.
Reviews on Recent Clinical Trials
Title:QT Prolongation and Anticancer Drugs: Is it a Cardiologist’s Worry? The Oncologist’s Point of View
Volume: 11 Issue: 3
Author(s): Francesca Aroldi, Tiziana Prochilo, Elena Bonini and Alberto Zaniboni
Affiliation:
Keywords: Adverse cardiac events, cancer, QT prolongation, through QT study, torsade de point.
Abstract: Currently, many novel therapies are available for physicians treating cancer; some of them are associated with adverse cardiac events. One of the most worrisome cardiac event is QT prolongation, which is a risk factor for developing the potentially fatal torsade de pointe. Many classes of drugs, both anticancer and concomitant agents, are involved in this issue. We report a review of old and new commonly used agents with torsadogenic potential.
Export Options
About this article
Cite this article as:
Aroldi Francesca, Prochilo Tiziana, Bonini Elena and Zaniboni Alberto, QT Prolongation and Anticancer Drugs: Is it a Cardiologist’s Worry? The Oncologist’s Point of View, Reviews on Recent Clinical Trials 2016; 11 (3) . https://dx.doi.org/10.2174/1574887111666160226150650
DOI https://dx.doi.org/10.2174/1574887111666160226150650 |
Print ISSN 1574-8871 |
Publisher Name Bentham Science Publisher |
Online ISSN 1876-1038 |
![](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Molecularly Imprinted Sol-Gel Materials for Medical Applications
Current Topics in Medicinal Chemistry Pleiotropic Effects of Statins - Clinical Evidence
Current Pharmaceutical Design Pharmacological Innovations for Posttraumatic Stress Disorder and Medication- Enhanced Psychotherapy
Current Pharmaceutical Design Efficacy of the Newest COX-2 Selective Inhibitors in Rheumatic Disease
Current Pharmaceutical Design Increased Paternal Age and Child Health and Development
Current Pediatric Reviews Diagnosis and Management of Chronic Coronary Artery Disease
Current Cardiology Reviews Berberine as a Potential Multi-Target Agent for Metabolic Diseases: A Review of Investigations for Berberine
Endocrine, Metabolic & Immune Disorders - Drug Targets Cardiac Toxicity in the Treatment of Light Chain Amyloidosis: Systematic Review of Clinical Studies
Current Drug Safety COVID-19: Our Current Knowledge of Epidemiology, Pathology, Therapeutic Approaches, and Diagnostic Methods
Anti-Cancer Agents in Medicinal Chemistry Editorial [Hot Topic: New Medicinal Chemistry Approaches for the Treatment of Cardiovascular Disease (Guest Editor: Dennis Lee)]
Current Topics in Medicinal Chemistry Chronotherapeutic Drug Delivery Systems - An Approach to Circadian Rhythms Diseases
Current Drug Delivery Evaluation of the Atherogenic Effect of Covid-19 Pneumonia on Coronary and Carotid Arteries in Patients who Recovered from the Disease
Current Medical Imaging Inflammasome and Atherogenesis
Current Pharmaceutical Design Small Molecule Antagonists of Chemokine Receptors - is Promiscuity a Virtue?
Current Topics in Medicinal Chemistry Respiratory Syncytial Virus Bronchiolitis and Asthma – Insights from Recent Studies and Implications for Therapy
Inflammation & Allergy - Drug Targets (Discontinued) Proinflammatory Gene Polymorphisms and Ischemic Stroke
Current Pharmaceutical Design Clinical Profile of Mortality among Chronic Schizophrenic Patients: A Local Pilot Survey in Iran
Current Psychiatry Research and Reviews Pulmonary Hypertension: Types and Treatments
Current Cardiology Reviews ICT for Telemedicine and Health Care Innovation
Recent Patents on Biomedical Engineering (Discontinued) Nanotechnology and Antioxidant Therapy: An Emerging Approach for Neurodegenerative Diseases
Current Medicinal Chemistry