Title:Nanofibre Based Smart Pharmaceutical Scaffolds for Wound Repair and Regenerations
Volume: 22
Issue: 11
Author(s): Charu Dwivedi, Himanshu Pandey, Avinash C. Pandey and Pramod W. Ramteke
Affiliation:
Keywords:
Chronic wounds, ulcer management, electrospun, nanofibrous scaffolds, wound healing, electrospinning, wound dressing, growth
factors.
Abstract: Chronic wounds and ulcers are posing a devastating manifestation on the socioeconomic status across
the globe along with the patient compliance. It reinforces a need for the development of successful alternative
treatments for the chronic wound care and ulcer management practices. This review explores the progressive
developments being made in the fabrication of electrospun nanofibrous scaffolds towards elimination of microbial
infection from chronic wounds to accelerate the wound healing process. Functional three dimensional nanofibrous
scaffolds produced by electrospinning have great potential in a wide spectrum of biomedical practices, such as
tissue engineering, drug/gene delivery and wound dressing. Moreover, this review also highlights the materials and
post modification methods, such as the functionaliation of electrospun nanofibrous scaffolds using growth factors, so that such smart and
bioactive nanofibrous scaffolds could be made suitable for wound healing applications.
