Title:Nanoliposome is a Promising Carrier of Protein and Peptide Biomolecule for the Treatment of Cancer
Volume: 16
Issue: 7
Author(s): Tapan Kumar Giri, Ayan Giri, Tapan Kumar Barman and Subhasis Maity
Affiliation:
Keywords:
Nanotechnology, protein, peptide, nanoliposome, targeting, cancer, parenteral delivery.
Abstract: Nano-liposomes are the newly developed delivery systems for cancer therapy that are finding a position
particularly suitable as peptide and protein carriers. These are three-layered self-assembled structures with
nanoparticulate carrier systems. The overall pharmacological properties of commonly used protein and peptide in
cancer therapy can be improved by the incorporation of protein and peptide into the nano-liposome. The surface
modifications can be made liposomes to make compatible with targeting ligands has made these nanocarriers for
targeted delivery. This review discusses the method of preparation and characterization of liposome based protein
peptide delivery for the treatment of cancer. This review also explores latest work intended for targeted treatment
of cancer by nano-liposomal protein and peptide delivery system. This type of delivery is targeting protein and
peptide to tumor site by avoiding the reticuloendothelial system. Methods of nano-liposome delivery containing protein and peptide are
also highlighted.
