Title:Design of multifunctional nanocarriers for delivery of anti-cancer therapy
Volume: 21
Issue: 42
Author(s): Neelesh Kumar Mehra, Keerti Jain and Narendra Kumar Jain
Affiliation:
Keywords:
Chemotherapy, multifunctional, dendrimers, carbon nanotubes, drug delivery, drug targeting.
Abstract: Chemotherapy is the major and most widely used therapeutic strategy for the treatment of a wide variety
of cancers. The non-specific/non-targeted drug delivery in chemotherapy leads to undesired side effects in
normal and healthy tissues, and insufficient dosages to kill cancerous cells. Now-a-days, smart and intelligent multifunctional
targeted nanomedicines based on various nanocarriers (dendrimers, carbon nanotubes, graphene,
nanoparticles, quantum dots, self-emuslifying lipidic systems and carbon nanohorns etc) are being investigated
promisingly in cancer treatment. In this article, we review the role of smart and intellegent multifucntional nanocarriers
in delivery of chemotherapeutic agents with the aim to develop promising treatment strategy to combat
with one of the killer of man kind i.e. cancer.