Abstract
Inflammation is a protective response to eliminate cytotoxic agents and pathogens. Various factors are thought to be involved in the pathological changes in tissues caused by inflammation. Interleukin 1, an inflammatory cytokine, is thought to have diverse physiological functions and to play an important role in inflammatory disease. In this review, we discuss interleukin-1 as a target of inflammatory disease.
Keywords: Infectious diseases, inflammasome, inflammation, interleukin-1β, receptors, tissue.
Endocrine, Metabolic & Immune Disorders - Drug Targets
Title:IL-1 as a target in inflammation
Volume: 15 Issue: 3
Author(s): Yuki Ito, Naoe Kaneko, Tomoyuki Iwasaki, Shinnosuke Morikawa, Kentaro Kaneko and Junya Masumoto
Affiliation:
Keywords: Infectious diseases, inflammasome, inflammation, interleukin-1β, receptors, tissue.
Abstract: Inflammation is a protective response to eliminate cytotoxic agents and pathogens. Various factors are thought to be involved in the pathological changes in tissues caused by inflammation. Interleukin 1, an inflammatory cytokine, is thought to have diverse physiological functions and to play an important role in inflammatory disease. In this review, we discuss interleukin-1 as a target of inflammatory disease.
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Cite this article as:
Ito Yuki, Kaneko Naoe, Iwasaki Tomoyuki, Morikawa Shinnosuke, Kaneko Kentaro and Masumoto Junya, IL-1 as a target in inflammation, Endocrine, Metabolic & Immune Disorders - Drug Targets 2015; 15 (3) . https://dx.doi.org/10.2174/1871530315666150316123657
DOI https://dx.doi.org/10.2174/1871530315666150316123657 |
Print ISSN 1871-5303 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3873 |
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