Title:Synthesis of New and Known Dicoumarols in Aqueous Media: A Green and Convenient Procedure Promoted by Titanium(IV) Oxide Nanoparticles
Volume: 11
Issue: 8
Author(s): Saeed Khodabakhshi, Mozhgan Shahamirian and Mojtaba Baghernejad
Affiliation:
Keywords:
Titanium(IV) oxide nanoparticles, chemoselectivity, 3, 3'-(2-aryl-2-oxoethylidene)bis[4-hydroxycoumarin]s, catalysts,
arylglyoxal.
Abstract: A simple and green method is reported for the completely chemoselective synthesis of some new dicoumarol
derivatives {3,3'-(2-aryl-2-oxoethylidene)bis[4-hydroxycoumarin]s} from the reaction of 4-hydroxycoumarin with arylglyoxals
in a molar ratio of 2:1 respectively. The reactions efficiently promoted by titanium(IV) oxide nanoparticles as a
heterogeneous catalyst via an on water process. Catalyst loading is very low and it shows recyclability.
