Title:Medicinal Electrochemistry: Integration of Electrochemistry, Medicinal Chemistry and Computational Chemistry
Volume: 21
Issue: 20
Author(s): M.O. Almeida, V.G. Maltarollo, R.A. de Toledo, H. Shim, M.C. Santos and K.M. Honorio
Affiliation:
Keywords:
Computational chemistry, electrochemistry, medicinal chemistry, QSAR, QSPR.
Abstract: Over the last centuries, there were many important discoveries in medicine that were crucial for gaining a better
understanding of several physiological processes. Molecular modelling techniques are powerful tools that have been successfully
used to analyse and interface medicinal chemistry studies with electrochemical experimental results. This special
combination can help to comprehend medicinal chemistry problems, such as predicting biological activity and understanding
drug action mechanisms. Electrochemistry has provided better comprehension of biological reactions and, as a result
of many technological improvements, the combination of electrochemical techniques and biosensors has become an appealing
choice for pharmaceutical and biomedical analyses. Therefore, this review will briefly outline the present scope
and future advances related to the integration of electrochemical and medicinal chemistry approaches based on various
applications from recent studies.