Title:Allergy and Inflammation: An Immunological and Therapeutic Approach
Volume: 7
Issue: 2
Author(s): Shyamji Shukla, Harshita Shukla, Suneel Kumar, Ravindra P. Aharwal, Vaibhav K. Gupta and Sardul S. Sandhu
Affiliation:
Keywords:
Allergy, antibodies, hypersensitivity, IgE, inflammation, macrophage, therapeutic.
Abstract: All organisms are protected by their immune system but occasionally this system overreacts leading to allergic
and inflammatory reactions in the body. These reactions are the starting points of various diseases like asthma, eczema
and urticaria etc. They involve activation of T cells, release of histamines, toxic chemicals from mast cells and eosinophils
respectively. Several chemically and naturally synthesized therapeutic agents are available for the treatment of these immunological
diseases. The present review provides a detailed account of mechanism of allergic and inflammatory reactions,
its types and various treatment strategies with a special focus on some recent patents in this field.