Title:PEG-600 Mediated Facile and Green Synthesis of Novel Imide Derivatives and Their Biological Activity Evaluation
Volume: 10
Issue: 3
Author(s): Yervala Dathu Reddy, Padam Praveen Kumar, Bhoomireddy Rama Devi, Pramod Kumar Dubey and Yalamanchili Bharathi Kumari
Affiliation:
Keywords:
Environmental sustainable synthesis; Antibacterial activity; Sodium salt of saccharin; Potassium salt of
phthalimide.
Abstract: Facile and green syntheses of novel 2-(1,2-benzisothiazole-3-one-1,1-dioxide)-N-arylacetamides, 2-(1,3-
dioxoisoindolin-2-yl)-N-arylacetamides and 2-(N-(2-oxo-2-(arylamino)ethyl)sulfamoyl (or) carbamoyl)benzoic acids have
been developed and tested for their biological activities against Baccilus megaterieum, Escherichia coli, Providencia
stuartii, Pseudomonas putida. Some of the synthesized compounds possess good activity against Escherichia coli and
Baccilus megaterieum compared to standard drugs.