Title:Biology of Circulating Nucleic Acids and Possible Roles in Diagnosis and Treatment in Diabetes and Cancer
Volume: 12
Issue: 5
Author(s): Peter B. Gahan
Affiliation:
Keywords:
Circulating DNA/RNA, plasma/serum, diabetes, cancer, diagnosis, nucleic acid uptake/expression, recipient cells, human plasma, human blood, severe sepsis, clinical patients, systemic lupus erythematosus patients, cancer patients, tumour cell derived, cardiovascular disease
Abstract: The presence of DNA and RNA circulating in human plasma and serum is described. The possible sources of
the DNA/RNA in blood, their ability to enter other cells and to express in the recipient cells are discussed and the relationship
with metastases considered. The possible role(s) of the DNA/RNA in clinical diagnosis, in monitoring treatment
and in prognosis are considered for diabetes and oncology.
