Syntheses of 2-benzylsubstituted Imidazo[1,2-a]pyrimidines Via Coupling – Cyclization Under Pd-Cu Catalysis

Title: Syntheses of 2-benzylsubstituted Imidazo[1,2-a]pyrimidines Via Coupling – Cyclization Under Pd-Cu Catalysis

Volume: 8 Issue: 6

Author(s): Mohammad Bakherad, Ali Keivanloo, Marzieh Mohammadi and Saeideh Jajarmi

Affiliation:

Keywords: Sonogashira coupling, aryl iodide, imidazo[1,2-a]pyrimidines, Pd-catalyzed, copper, palladium, alkynes, aryl, carboannulation, heteroannulation

Abstract: The reaction of 1-(prop-2-yn-1yl)pyrimidin-2(1H)-imin with various halobenzenes in the presence of a palladium catalyst leads to the production of 2-benzylsubstituted imidazo[1,2-a]pyrimidines.

Cite this article as:

Bakherad Mohammad, Keivanloo Ali, Mohammadi Marzieh and Jajarmi Saeideh, Syntheses of 2-benzylsubstituted Imidazo[1,2-a]pyrimidines Via Coupling – Cyclization Under Pd-Cu Catalysis, Letters in Organic Chemistry 2011; 8 (6) . https://dx.doi.org/10.2174/157017811796064368