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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of Novel Isoxazolidines and Medium-Ring Heterocycles Oxazocines and Oxazonines

Author(s): Brindaban Roy, Rajendra N. De and Somjit Hazra

Volume 8, Issue 6, 2011

Page: [391 - 400] Pages: 10

DOI: 10.2174/157017811796064502

Price: $65

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Abstract

A number of novel oxa-bridged and methylene oxa-bridged bicyclic isoxazolidines have been synthesized using intramolecular nitrone cycloaddition. The reductive cleavage of N-O bonds of the isoxazolidines to provide novel medium-ring heterocycles oxazocines and oxazonines is also described.

Keywords: Isoxazolidines, oxazocines, oxazonines, amino alcohols, medium-ring heterocycles, oxa-bridged, methylene, nitrone, cycloaddition, benzoxazocine


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