Title: Synthesis of Novel Isoxazolidines and Medium-Ring Heterocycles Oxazocines and Oxazonines
Volume: 8
Issue: 6
Author(s): Brindaban Roy, Rajendra N. De and Somjit Hazra
Affiliation:
Keywords:
Isoxazolidines, oxazocines, oxazonines, amino alcohols, medium-ring heterocycles, oxa-bridged, methylene, nitrone, cycloaddition, benzoxazocine
Abstract: A number of novel oxa-bridged and methylene oxa-bridged bicyclic isoxazolidines have been synthesized using intramolecular nitrone cycloaddition. The reductive cleavage of N-O bonds of the isoxazolidines to provide novel medium-ring heterocycles oxazocines and oxazonines is also described.