Synthesis and Anticoccidial Activity of 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) Quinazolinone Derivatives

Title: Synthesis and Anticoccidial Activity of 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) Quinazolinone Derivatives

Volume: 7 Issue: 6

Author(s): Yuanyuan Zhang, Guangmin Chen, Yabiao Weng, Renliang Li, Yuliang Wang and Yuzhong Wang

Affiliation:

Keywords: 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) quinazolinone, Derivatives, Synthesis, Anticoccidial activity, Eimeria tenella

Abstract: A series of 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) quinazolinone derivatives (8a-k) were designed and synthesized. Their anticoccidial activities were evaluated against Eimeria tenella in vivo. The results indicated that compounds 8a, 8b and 8e exhibited anticoccidial activity against Eimeria tenella in the chickens diet with a dose of 18 mg/Kg.

Cite this article as:

Zhang Yuanyuan, Chen Guangmin, Weng Yabiao, Li Renliang, Wang Yuliang and Wang Yuzhong, Synthesis and Anticoccidial Activity of 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) Quinazolinone Derivatives, Letters in Drug Design & Discovery 2010; 7 (6) . https://dx.doi.org/10.2174/157018010791306498

DOI https://dx.doi.org/10.2174/157018010791306498	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X