Ceric Ammonium Nitrate: An Efficient Catalyst for One-Pot Synthesis of 2,2,4-Trimethyl-1,2-dihydroquinolines

Title: Ceric Ammonium Nitrate: An Efficient Catalyst for One-Pot Synthesis of 2,2,4-Trimethyl-1,2-dihydroquinolines

Volume: 7 Issue: 4

Author(s): Shylaprasad Durgadas, Vijay K. Chatare, Khagga Mukkanti and Sarbani Pal

Affiliation:

Keywords: CAN, catalysis, aniline, dihydroquinoline

Abstract: Ceric ammonium nitrate (CAN) catalyzed the one-pot synthesis of 2,2,4-trimethyl-1,2-dihydroquinoline derivatives from substituted anilines and acetone via a modified Skraup reaction. The methodology was used to synthesize a novel dihydroquinoline-based compound derived from an anti-inflammatory agent nimesulide.

Cite this article as:

Durgadas Shylaprasad, K. Chatare Vijay, Mukkanti Khagga and Pal Sarbani, Ceric Ammonium Nitrate: An Efficient Catalyst for One-Pot Synthesis of 2,2,4-Trimethyl-1,2-dihydroquinolines, Letters in Organic Chemistry 2010; 7 (4) . https://dx.doi.org/10.2174/157017810791130586