Title: Rapid Synthesis of Taxifolione and Taxifolial D, Two Metabolites from the Marine Alga Caulerpa taxifolia
Volume: 6
Issue: 1
Author(s): Fabien Fecourt, Cedric Carlier and Patrick Pale
Affiliation:
Keywords:
Terpenoids, enynes, cross-coupling, antitumor agents
Abstract: The synthesis of two natural products - Taxifolione and Taxifolial D – isolated from the marine alga Caulerpa taxifolia invading the Mediterranean Sea was performed. Coupling reactions allowed for a rapid synthesis. The surprising Z configuration of Taxifolial D was confirmed after synthesis and comparison of each synthetic stereoisomer.