Title: Three Components Coupling Catalysed by Na2CaP2O7: Synthesis of α-Amino Phosphonates Under Solvent-Free Conditions at Room Temperature
Volume: 2
Issue: 5
Author(s): M. Zahouily, A. Elmakssoudi, A. Mezdar, A. Rayadh, S. Sebti and H. B. Lazrek
Affiliation:
Keywords:
synthetic phosphate, amino phosphonates, heterogeneous catalysis, recyclable catalyst
Abstract: Synthetic phosphate Na2CaP2O7 has been utilized as an efficient catalyst for the three components coupling of carbonyl compounds, aromatic and aliphatic amines and dialkyl phosphite to produce α-amino phosphonates. The reaction was carried out under solvent-free conditions at room temperature. The by-product H2O formed during the reaction increases the catalytic activity of Na2CaP2O7.