Title: Gold-Catalyzed Coupling of Alkynes and Acyl Iminiums
Volume: 2
Issue: 5
Author(s): Chunmei Wei and Chao-Jun Li
Affiliation:
Keywords:
propargyl amines, enantioselective synthesis, copper-catalyzed addition, solid-phase mannich condensation, copper-mediated coupling, diisopropylethylamine
Abstract: A gold-catalyzed direct addition of alkynes to active acyl iminium ion, which was generated in situ with an acid chloride, to afford a propargylamides in excellent yields.
