Title: A Simple Asymmetric Synthesis of 4-Substituted-2-Oxazolidinones
Volume: 2
Issue: 7
Author(s): V. J. Sattigeri, A. S.S.V. Srinivas, A. Soni, J. M. Khanna and A. Mehta
Affiliation:
Keywords:
chiral, substituted -oxazolidinones, asymmetric dihydroxylation, intramolecular cyclisation
Abstract: A novel and efficient synthesis of 4-substituted 2-oxazolidinones is described; the synthesis utilizes Sharpless asymmetric dihydroxylation (AD) of appropriately substituted O-allylcarbamates and intramolecular cyclisation as key steps.