Title: Design Features that Affect Psychopharmacology Trials
Volume: 2
Issue: 7
Author(s): Arif Khan and Kelly Schwartza
Affiliation:
Keywords:
investigational psychopharmacological agent, Antidepressant, placebo, Clinical Trials, obsessive compulsive disorder (OCD)
Abstract: The patients psychiatric diagnoses play a large role in the design and outcome of psychopharmacology clinical trials. Among antidepressant trials, magnitude of placebo response, initial severity of depression, dosing regimen, number of treatment arms and duration of trial, choice of rating scales, and sex of the patient may influence antidepressant trial outcome.
