Title: Suzuki-Miyaura Cross-Coupling Reaction in the Functionalization of the C Ring of Morphinans
Volume: 4
Issue: 2
Author(s): Attila Sipos and Sandor Berenyi
Affiliation:
Keywords:
Suzuki-Miyaura cross-coupling of tosylates and mesylates, spatially hindered position, 14-arylmorphinan, opioid receptor binding affinity, microwave activation
Abstract: New methods have been developed for the functionalization of the non-aromatic C ring of morphinans with Suzuki-Miyaura cross-coupling of sulfonates and bromides.