![conference banner](/images/conference-banner.jpeg)
Abstract
The genus Marrubium (Lamiaceae) is comprised of about forty species, distributed in Europe, Asia and Brazil. Some species are traditionally used to treat various diseases, including asthma, pulmonary infections, inflammation and hypotension, as cholagogues and sedative agents, and for pain relief. A literature review on the chemical and biological aspects of these plants indicates antimicrobial activity against gram positive bacteria, analgesic properties, and anti-hypertensive, antidiabetic, antioxidant properties, among others, particularly related to the presence of diterpenes, sterols, phenylpropanoids and flavonoids. This review shows the main chemical and pharmacological aspects of the genus Marrubium, with emphasis on M. vulgare, which grows in Brazil and has been studied by us and other authors.
Keywords: Marrubium, ethnopharmacology, chemical composition, M. vulgare, labdane terpenes, essential oils, analgesic and anti-inflammatory effects, antimicrobial, Lamiaceae, asthma, pulmonary infections, inflammation, hypotension, cholagogues, gram positive bacteria, analgesic properties, anti-hypertensive, antidiabetic, antioxidant properties, diterpenes, sterols, phenylpropanoids, flavonoids, analgesic andchemical, anti-inflammatory effects, antimicrobial, Marrubium vulgare, polyphenols, Marrubium alysson L, sitosterol glucoside (1), apigenin-7-O-arabonoside, apigenin-7-O-glucoside, verbascoside, leucosceptoside A, forsythoside B, leucosceptoside B, M. alysson, Candida glabrata, C. albicans, C. parapsilosis, C. kreusei, oleanolic, Lamiaceae family, Marrubium alternidens Rech, tannins, alkaloids, Marrubium astracanicum Jacq, beta-caryophyllene, valeranone, Marrubium bourgaei Boiss. ssp Caricum P.H., Eugenol, bisabolene, saponins, prefuranic labdane diterpene
Current Pharmaceutical Design
Title: A Review of the Chemical and Pharmacological Aspects of the Genus Marrubium
Volume: 16 Issue: 31
Author(s): Christiane Meyre-Silva and Valdir Cechinel-Filho
Affiliation:
Keywords: Marrubium, ethnopharmacology, chemical composition, M. vulgare, labdane terpenes, essential oils, analgesic and anti-inflammatory effects, antimicrobial, Lamiaceae, asthma, pulmonary infections, inflammation, hypotension, cholagogues, gram positive bacteria, analgesic properties, anti-hypertensive, antidiabetic, antioxidant properties, diterpenes, sterols, phenylpropanoids, flavonoids, analgesic andchemical, anti-inflammatory effects, antimicrobial, Marrubium vulgare, polyphenols, Marrubium alysson L, sitosterol glucoside (1), apigenin-7-O-arabonoside, apigenin-7-O-glucoside, verbascoside, leucosceptoside A, forsythoside B, leucosceptoside B, M. alysson, Candida glabrata, C. albicans, C. parapsilosis, C. kreusei, oleanolic, Lamiaceae family, Marrubium alternidens Rech, tannins, alkaloids, Marrubium astracanicum Jacq, beta-caryophyllene, valeranone, Marrubium bourgaei Boiss. ssp Caricum P.H., Eugenol, bisabolene, saponins, prefuranic labdane diterpene
Abstract: The genus Marrubium (Lamiaceae) is comprised of about forty species, distributed in Europe, Asia and Brazil. Some species are traditionally used to treat various diseases, including asthma, pulmonary infections, inflammation and hypotension, as cholagogues and sedative agents, and for pain relief. A literature review on the chemical and biological aspects of these plants indicates antimicrobial activity against gram positive bacteria, analgesic properties, and anti-hypertensive, antidiabetic, antioxidant properties, among others, particularly related to the presence of diterpenes, sterols, phenylpropanoids and flavonoids. This review shows the main chemical and pharmacological aspects of the genus Marrubium, with emphasis on M. vulgare, which grows in Brazil and has been studied by us and other authors.
Export Options
About this article
Cite this article as:
Meyre-Silva Christiane and Cechinel-Filho Valdir, A Review of the Chemical and Pharmacological Aspects of the Genus Marrubium, Current Pharmaceutical Design 2010; 16 (31) . https://dx.doi.org/10.2174/138161210793563392
DOI https://dx.doi.org/10.2174/138161210793563392 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
Call for Papers in Thematic Issues
Blood-based biomarkers in large-scale screening for neurodegenerative diseases
Disease biomarkers are necessary tools that can be employ in several clinical context of use (COU), ranging from the (early) diagnosis, prognosis, prediction, to monitor of disease state and/or drug efficacy. Regarding neurodegenerative diseases, in particular Alzheimer’s disease (AD), a battery of well-validated biomarkers are available, such as cerebrospinal fluid ...read more
Current Pharmaceutical challenges in the treatment and diagnosis of neurological dysfunctions
Neurological dysfunctions (MND, ALS, MS, PD, AD, HD, ALS, Autism, OCD etc..) present significant challenges in both diagnosis and treatment, often necessitating innovative approaches and therapeutic interventions. This thematic issue aims to explore the current pharmaceutical landscape surrounding neurological disorders, shedding light on the challenges faced by researchers, clinicians, and ...read more
Diabetes mellitus: advances in diagnosis and treatment driving by precision medicine
Diabetes mellitus (DM) is a chronic degenerative metabolic disease with ever increasing prevalence worldwide which is now an epidemic disease affecting 500 million people worldwide. Insufficient insulin secretion from pancreatic β cells unable to maintain blood glucose homeostasis is the main feature of this disease. Multifactorial and complex nature of ...read more
Emerging and re-emerging diseases
Faced with a possible endemic situation of COVID-19, the world has experienced two important phenomena, the emergence of new infectious diseases and/or the resurgence of previously eradicated infectious diseases. Furthermore, the geographic distribution of such diseases has also undergone changes. This context, in turn, may have a strong relationship with ...read more
![Wayfinder Image](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Headache: One of the Most Common and Troublesome Adverse Reactions to Drugs
Current Drug Safety Neuroprotective Role of Agmatine in Neurological Diseases
Current Neuropharmacology Targeting Established Tumor Vasculature: A Novel Approach to Cancer Treatment
Current Cancer Therapy Reviews Radiolabeled Probes Targeting Tyrosine-Kinase Receptors For Personalized Medicine
Current Pharmaceutical Design Safety Limits of Antidepressant Use Plus Combinations: Focus on Cardiovascular Function
Current Drug Metabolism Interventions Against Sarcopenia in Older Persons
Current Pharmaceutical Design The Trigeminocardiac Reflex as Oxygen Conserving Reflex in Humans: Its Ischemic Tolerance Potential
Vascular Disease Prevention (Discontinued) Regulation of Adrenomedullin and its Family Peptide by RAMP System – Lessons from Genetically Engineered Mice
Current Protein & Peptide Science Atypical Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children: A Systematic Review
Current Pediatric Reviews Isolation and Identification of an Angiotensin-I Converting Enzyme Inhibitory Peptide from Yeast (Saccharomyces cerevisiae)
Current Analytical Chemistry Neurogenesis and Sensorimotor Gating: Bridging a Microphenotype and an Endophenotype
Current Molecular Medicine Management of Anaphylaxis in Pediatric Population
Current Pharmaceutical Design Natriuretic Peptide Family: New Aspects
Current Medicinal Chemistry - Cardiovascular & Hematological Agents The Use of Nitric Oxide Synthase Inhibitors in Inflammatory Diseases: A Novel Class of Anti-Inflammatory Agents
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents Neurohypophyseal Dysfunction During Septic Shock
Endocrine, Metabolic & Immune Disorders - Drug Targets Development of Poly(lactide-co-glicolide) Nanoparticles Incorporating Morphine Hydrochloride to Prolong its Circulation in Blood
Current Pharmaceutical Design Comparative Biochemical Studies of Myotoxic Phospholipase A2 From Bothrops Venom
Protein & Peptide Letters Bioorganic Compounds Produced by the Fungus Monascus and their Use in Health Sciences and Medicine
Mini-Reviews in Organic Chemistry Omega-3 and Renal Function in Older Adults
Current Pharmaceutical Design Emerging Roles for Connexins in Hypertension
Current Hypertension Reviews