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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Research Article

Solvent-free Simplistic Synthesis of Bis(indolyl) Methanes Using Tulsion®- 8052 MP Resin

Author(s): Suhas Sadaphal, Sanjay Gaikwad, Shubham Dagale, Suryakant Sapkal*, Pratibha Randhavane and Jaishree Gawai

Volume 22, Issue 3, 2025

Published on: 23 July, 2024

Page: [222 - 227] Pages: 6

DOI: 10.2174/0115701786318532240722113525

Price: $65

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Abstract

Tulsion®-8052 MP cation resin catalyst accelerates chemical reaction by creating a suitable environment for the aldehyde and indole reactants to interact and form desired product bis(indolyl) methanes in solvent-free room temperature conditions. The uniqueness of this catalytic method is that it is eco-friendly, recyclable, selective, and operates on a variety of functional groups with good to excellent yield at room temperature conditions without the use of any hazardous solvents, high temperature, and inert atmosphere.

Keywords: Tulsion®-8052 MP resin, indoles, aldehydes, bis(indolyl)methanes (BIM’s), room temperature, solvent-free synthesis.


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