Title:Utilizing NCP@PO(OH)2 as a Core-Shell Magnetic Nano-Catalyst for the
Conversion of β-Hydroxy Nitrile to α,β-Unsaturated Carboxylic Acid
Volume: 22
Issue: 1
Author(s): Farzaneh Ebrahimzadeh*
Affiliation:
- Department of Chemistry, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Keywords:
Core-shell, nanocatalyst, modified chitosan, β-hydroxy nitrile, α, β-unsaturated carboxylic acid, magnetic nanocomposite, regioselective synthesis, heterogeneous catalysis.
Abstract: The synthesis of α,β-unsaturated compounds is crucial in organic chemistry, especially in
drug discovery and pharmaceutical development. In this study, NCP@POCl2-x (Fe3O4@SiO2@ chitosan@POCl2-x) has been introduced as a new, environmentally friendly, and highly efficient
heterogeneous magnetic nanocatalyst for the synthesis of α,β-unsaturated carboxylic acids. This catalyst
facilitates the in situ transformation of POCl