Title:Niosomes as a Promising Therapeutic Approach against Colorectal Cancer: A
Focus on the Delivery of Chemotherapeutics and Natural Products
Volume: 30
Issue: 21
Author(s): Samaneh Mollazadeh, Abdulridha Mohammed Al-Asady, Amirhosein Barjasteh, Hanieh Latifi, Amir Avan, Majid Khazaei, Mikhail Ryzhikov and Seyed Mahdi Hassanian*
Affiliation:
- Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
- Department
of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Keywords:
Colorectal cancer, niosomes, nanoparticles, chemotherapeutics, natural products, nanotechnology.
Abstract: Nanotechnology has emerged as an effective approach to cancer treatment, including Colorectal
Cancer (CRC). While conventional treatments, such as chemotherapeutic agents, are used to manage CRC,
their efficacy can be improved using drug delivery systems that enhance their bioavailability and reduce side
effects. Niosomes, polymeric nanoparticles, have shown promise as biocompatible vehicles that can transport
hydrophilic and lipophilic molecules. This can result in reduced drug dosage and increased efficacy. This review
examines the use of niosomal formulations as a delivery platform for treating CRC and provides practical
insights into their clinical applications.