Title:The Regulation of Selenoproteins in Diabetes: A New Way to Treat Diabetes
Volume: 30
Issue: 20
Author(s): Jing Liang, Yiwen He, Chunxia Huang, Fengjie Ji, Xihong Zhou*Yulong Yin*
Affiliation:
- Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of
Sciences, Changsha 410125, China
- College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing
100049, China
- Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of
Sciences, Changsha 410125, China
- College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing
100049, China
Keywords:
Glucose metabolism, lipid metabolism, selenium, selenoproteins, diabetes, micronutrient.
Abstract: Selenium is an essential micronutrient required for the synthesis and function of selenoproteins,
most of which are enzymes involved in maintaining oxidative balance in the body. Diabetes is a group of
metabolic disorders characterized by high blood glucose levels over a prolonged period of time. There are
three main types of diabetes: type 1, type 2, and gestational diabetes. This review summarizes recent advances
in the field of diabetes research with an emphasis on the roles of selenoproteins on metabolic disturbance in diabetes.
We also discuss the interaction between selenoproteins and glucose and lipid metabolism to provide
new insights into the prevention and treatment of diabetes.